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KLK3 / PSA

kallikrein-related peptidase 3

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Seum levels of KLK3 (also known as PSA) are useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Gene Name: kallikrein-related peptidase 3
Family/Subfamily: Protease , Serine S1
Synonyms: KLK3, APS, Gamma-seminoprotein, Kallikrein-3, Kallikrein-related peptidase 3, P-30 antigen, Prostate specific antigen, Prostate-specific antigen, PSA, Semenogelase, KLK2A1, Seminin
Target Sequences: NM_001648 NP_001639.1 P07288

Publications (1)

1
Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells. Morrissey C, Gallis B, Solazzi JW, Kim BJ, Gulati R, Vakar-Lopez F, Goodlett DR, Vessella RL, Sasaki T. Anti-cancer drugs. 2010 21:423-32. (WB) [PubMed:20130467] [PMC:PMC2953769]

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Products
Antibodies (242)
Primary (242)
KLK3 / PSA (242)
Human (233)
Mouse (12)
Rat (10)
IHC (76)
IHC-Fr (11)
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rabbit (52)
mouse (170)
goat (7)
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113 (1)
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No (242)
KLK3 / PSA Antibody - Anti-KLK3 / PSA antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 1:200.
Select
KLK3 / PSA Mouse anti-Human Monoclonal (aa26-251) (5A11E2) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Select
KLK3 / PSA Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA
HRP Conjugated
50 µg/$294; 100 µg/$360
Select
KLK3 / PSA Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
Select
KLK3 / PSA Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
KLK3 / PSA Antibody - Anti-PSA antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
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Cancer Pathology
Cancer
KLK3 / PSA Mouse-Balb/c anti-Human Monoclonal (C3F12) Antibody
Human
ELISPOT, Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$485
KLK3 / PSA Antibody - Immunohistochemistry of paraffin-embedded mouse kidney tissue.
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KLK3 / PSA Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
KLK3 / PSA Antibody - Anti-PSA antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Select
Cancer Pathology
Cancer
KLK3 / PSA Mouse-Balb/c anti-Human Monoclonal (1A7) Antibody
Human
ELISPOT, Flo, ICC, IHC, IHC-Fr, IHC-P
Unconjugated
100 µg/$485
Select
KLK3 / PSA Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
1 mg/$392
KLK3 / PSA Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer Pathology
Cancer
KLK3 / PSA Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Human
IHC-P, WB
Unconjugated
50 µl/$460
KLK3 / PSA Antibody - HKLK3 Antibody (C234) western blot of A549 cell line lysates (35 ug/lane). The HKLK3 antibody detected the HKLK3 protein (arrow).
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KLK3 / PSA Mouse anti-Human Monoclonal (aa220-250) Antibody
Human
WB
Unconjugated
0.1 ml/$393
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KLK3 / PSA Rabbit anti-Human Polyclonal (50-130 aa, Internal) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
KLK3 / PSA Antibody - Anti-PSA antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Select
Cancer Pathology
Cancer
KLK3 / PSA Mouse-Balb/c anti-Human Monoclonal (3E6) Antibody
Human
ELISPOT, Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$485
Select
KLK3 / PSA Mouse anti-Human Monoclonal (Biotin) (A67-B/E3) Antibody
Human
ELISA, IHC-P, WB
Biotin Conjugated
0.1 mg/$326
KLK3 / PSA Antibody - Anti-KLK3 / PSA antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
Select
Cancer Pathology
Cancer
KLK3 / PSA Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC, IHC-P, IRMA
Unconjugated
0.1 mg/$460
KLK3 / PSA Antibody - Anti-PSA antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 10 ug/ml.
Select
Cancer Pathology
Cancer
KLK3 / PSA Mouse-Balb/c anti-Human Monoclonal (2B7) Antibody
Human
ELISA, Flo, ICC, IHC, IHC-Fr, IHC-P, WB
Unconjugated
0.1 mg/$485
Select
KLK3 / PSA Mouse anti-Human Monoclonal (214) Antibody
Human
ELISA
Unconjugated
1 mg/$712
KLK3 / PSA Antibody - Anti-KLK3 / PSA antibody IHC staining of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Select
KLK3 / PSA Mouse anti-Human Monoclonal (AT1D10) Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
KLK3 / PSA Antibody - Prostate Specific Antigen PSA antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
KLK3 / PSA Mouse anti-Human Monoclonal (A67-B/E3) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated
20 µg/$371; 100 µg/$574
KLK3 / PSA Antibody - Prostate Specific Antigen PSA antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
KLK3 / PSA Mouse anti-Human Monoclonal (Azide-free, BSA-free) (A67-B/E3) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Azide-free, BSA-free
100 µg/$574
KLK3 / PSA Antibody - Prostate Specific Antigen PSA antibody immunohistochemistry.  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
KLK3 / PSA Mouse anti-Human Monoclonal (Ready-to-Use) (A67-B/E3) Antibody
Human
ELISA, Flo, IF, IHC, IHC-P, IP, WB
Unconjugated, Ready-to-Use
7 ml/$574
KLK3 / PSA Antibody - Formalin-fixed, paraffin-embedded human prostate carcinoma stained with PSA antibody (KLK3/801 + KLK3/1248).  This image was taken for the unmodified form of this product. Other forms have not been tested.
Select
KLK3 / PSA Mouse anti-Human Monoclonal (KLK3/801 + KLK3/1248) Antibody
Human
Flo, IF, IHC, IHC-P
Unconjugated
20 µg/$371; 100 µg/$574
Select
KLK3 / PSA Mouse anti-Human Monoclonal Antibody
Human
ELISA, IHC
Unconjugated
100 µg/$361
KLK3 / PSA Antibody - IHC of Prostate-Specific Antigen on FFPE Prostatic Adenocarcinoma tissue.
Select
KLK3 / PSA Mouse anti-Human Monoclonal Antibody
Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$314
KLK3 / PSA Antibody - Immunohistochemical analysis of Kallikrein 3 staining in human breast cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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KLK3 / PSA Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
Select
KLK3 / PSA Sheep anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
1 mg/$470; 10 mg/$2,757
Viewing 1-25 of 242 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).