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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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KLK3 / PSA

kallikrein-related peptidase 3

Kallikreins are a subgroup of serine proteases having diverse physiological functions. Growing evidence suggests that many kallikreins are implicated in carcinogenesis and some have potential as novel cancer and other disease biomarkers. This gene is one of the fifteen kallikrein subfamily members located in a cluster on chromosome 19. Its protein product is a protease present in seminal plasma. It is thought to function normally in the liquefaction of seminal coagulum, presumably by hydrolysis of the high molecular mass seminal vesicle protein. Seum levels of KLK3 (also known as PSA) are useful in the diagnosis and monitoring of prostatic carcinoma. Alternate splicing of this gene generates several transcript variants encoding different isoforms.

Gene Name: kallikrein-related peptidase 3
Family/Subfamily: Protease , Serine S1
Synonyms: KLK3, APS, Gamma-seminoprotein, Kallikrein-3, Kallikrein-related peptidase 3, P-30 antigen, Prostate specific antigen, Prostate-specific antigen, PSA, Semenogelase, KLK2A1, Seminin
Target Sequences: NM_001648 NP_001639.1 P07288

Publications (1)

1
Effect of artemisinin derivatives on apoptosis and cell cycle in prostate cancer cells. Morrissey C, Gallis B, Solazzi JW, Kim BJ, Gulati R, Vakar-Lopez F, Goodlett DR, Vessella RL, Sasaki T. Anti-cancer drugs. 2010 21:423-32. (WB) [PubMed:20130467] [PMC:PMC2953769]

☰ Filters
Products
Proteins (16)
Native (2)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (2)
Recombinant (11)
KLK3 / PSA (16)
No (16)
6His, C-terminus (4)
6His, N-terminus (2)
GST (1)
His (3)
His, N-Terminal (1)
Myc-DDK (Flag) (3)
Human (14)
Mouse (1)
293T Cells (1)
E. coli (4)
HEK 293 Cells (3)
Human (1)
Human Cells (3)
Mammalian Cells (2)
Wheat Germ Extract (1)
Purified (4)
Low endotoxin level (5)
KLK3 / PSA Protein - Recombinant Kallikrein 3 By SDS-PAGE
Select
E. coli
His
26.3 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
Select
Human
None
30 kDa
0.1 mg/$493
KLK3 / PSA Protein
Select
E. coli
His
100 µg/$361; 500 µg/$739; 20 µg/$261
KLK3 / PSA Protein - 12.5% SDS-PAGE of human KLK3 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
54.45 kDa
10 µg/$479; 25 µg/$670
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
27.1kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,353
KLK3 / PSA Protein - Purified recombinant protein KLK3 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
26.8 kDa
20 µg/$1,107
Select
None
30 kDa
0.2 mg/$584
Select
HEK 293 Cells
6His, N-terminus
30 kDa
200 µl/$283
Select
293T Cells
Myc-DDK (Flag)
28.74 kDa
20 µg/$150
KLK3 / PSA Protein - Recombinant Kallikrein 3 (KLK3) by SDS-PAGE
Select
E. coli
His, N-Terminal
27.6kDa
10 µg/$288; 50 µg/$487; 200 µg/$972; 100 µg/$780; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
KLK3 / PSA Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
28.74 kDa
100 µg/$494
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
27.9 kDa
10 µg/$317; 50 µg/$524
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
27.1 kDa
10 µg/$344; 50 µg/$584
Select
Human Cells
His
Less than 1.0 EU/µg protein (determined by LAL method).
28.3 kDa
50 µg/$854
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
27.88kD
10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157
KLK3 / PSA Protein
Select
E. coli
6His, N-terminus
29 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Viewing 1-16 of 16 product results


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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).