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Infectious Disease
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Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
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Customer Service: (800) 227-6666 / (650) 697-3600
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KNG1 / Kininogen / Bradykinin
kininogen 1
1 Kininogens are inhibitors of thiol proteases; (2) HMW-kininogen plays an important role in blood coagulation by helping to position optimally prekallikrein and factor XI next to factor XII; (3) HMW-kininogen inhibits the thrombin- and plasmin-induced aggregation of thrombocytes; (4) the active peptide bradykinin that is released from HMW-kininogen shows a variety of physiological effects: (4A) influence in smooth muscle contraction, (4B) induction of hypotension, (4C) natriuresis and diuresis, (4D) decrease in blood glucose level, (4E) it is a mediator of inflammation and causes (4E1) increase in vascular permeability, (4E2) stimulation of nociceptors (4E3) release of other mediators of inflammation (e.g. prostaglandins), (4F) it has a cardioprotective effect (directly via bradykinin action, indirectly via endothelium-derived relaxing factor action); (5) LMW-kininogen inhibits the aggregation of thrombocytes; (6) LMW-kininogen is in contrast to HMW-kininogen not involved in blood clotting.
| Gene Name: | kininogen 1 |
| Synonyms: | KNG1, Bradykinin, Flaujeac factor deficiency, Fitzgerald factor, Kininogen 1, Kininogen-1, Kininogen, BDK, HMWK, KNG |
| Target Sequences: | NM_000893 NP_000884.1 P01042 |
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Products
Antibodies
(127)
Type
Primary
(127)
Target
KNG1 / Kininogen / Bradykinin
(127)
Reactivity
Human
(110)
Mouse
(37)
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(22)
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(1)
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(9)
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(3)
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(6)
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(3)
Monkey
(10)
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(6)
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(8)
Application
IHC
(22)
IHC-P
(15)
WB
(110)
Flo
(6)
ELISA
(38)
ICC
(2)
ID
(1)
IF
(4)
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(2)
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(1)
Peptide-ELISA
(3)
Host
rabbit
(108)
mouse
(16)
goat
(3)
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(2)
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(3)
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(3)
Isotype
IgG
(43)
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(3)
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(2)
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(1)
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(1)
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(4)
Clonality
monoclonal mc
(15)
polyclonal pc
(112)
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06
(1)
09
(1)
15C7-4F7
(1)
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(1)
16E4-H1
(1)
17A12-F12
(1)
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(2)
17F8-F10
(1)
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(1)
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(1)
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(1)
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APC
(6)
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(8)
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(15)
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(6)
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(6)
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(14)
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(12)
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(8)
Preservative Free
(5)
Unconjugated
(58)
Epitope
aa22-379
(8)
aa390-644
(8)
aa138-166
(7)
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(4)
aa251-300
(4)
aa40-89
(4)
300-380 aa, Internal
(1)
aa1-416
(1)
aa19-210
(1)
aa227-259
(1)
aa268-279
(1)
aa378-430
(1)
aa58-70
(1)
heavy chain, Cleaved-Lys380
(1)
Publications
No
(127)
KNG1 / Kininogen / Bradykinin Mouse anti-Human Monoclonal (2B5) Antibody
Human
ELISA, WB
Unconjugated
200 µg/$672
Cancer Pathology
Cancer
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa1-416) Antibody
Human
ICC, IHC-P, WB
Unconjugated
50 µl/$440
KNG1 / Kininogen / Bradykinin Rabbit anti-Mouse Polyclonal (aa227-259) Antibody
Mouse
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
KNG1 / Kininogen / Bradykinin Mouse anti-Human Monoclonal (C11C1) Antibody
Human
ELISA, Neut, WB
Unconjugated
200 µg/$672
Cancer Pathology
Cancer
KNG1 / Kininogen / Bradykinin Goat anti-Human Polyclonal (aa58-70) Antibody
Human
IHC-P, Peptide-ELISA, WB
Unconjugated
50 µg/$485
Cancer Pathology
Cancer
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa251-300) Antibody
Human
IHC-P, WB
Unconjugated
100 µl/$485
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (300-380 aa, Internal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa138-166) Antibody
Human
ELISA, Flo, IHC, WB
Unconjugated
200 µl/$734
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa138-166) (Biotin) Antibody
Human
ELISA, Flo, IHC, WB
Biotin Conjugated
200 µl/$952
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa138-166) (APC) Antibody
Human
ELISA, Flo, IHC, WB
APC Conjugated
200 µl/$952
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa138-166) (PE) Antibody
Human
ELISA, Flo, IHC, WB
PE Conjugated
200 µl/$952
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa138-166) Antibody
Human
Flo, IHC, IHC-P, WB
Unconjugated
200 µl/$460
KNG1 / Kininogen / Bradykinin Mouse anti-Human Monoclonal (4A1) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$423
KNG1 / Kininogen / Bradykinin Goat anti-Human Polyclonal (aa268-279) Antibody
Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µg/$503
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA
Unconjugated
400 µg/$878
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal Antibody
Mouse, Human
WB
Unconjugated
100 µg/$749
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa40-89) Antibody
Human
WB
Unconjugated
100 µl/$424
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa40-89) (HRP) Antibody
Dog, Human, Monkey, Chimpanzee, Orangutan, Gibbon
WB
HRP Conjugated
100 µl/$469
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (aa390-644) Antibody
Human
WB
Unconjugated
100 µl/$303; 200 µl/$343; 500 µl/$476; 1 ml/$543; 2 ml/$715; 5 ml/$1,182
KNG1 / Kininogen / Bradykinin Mouse anti-Human Monoclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$371
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
100 µg/$351
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
KNG1 / Kininogen / Bradykinin Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
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of 127
product results
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