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KRT14 / CK14 / Cytokeratin 14

keratin 14

KRT14 / CK14 / Cytokeratin 14 is a member of the keratin family, the most diverse group of intermediate filaments. This gene product, a type I keratin, is usually found as a heterotetramer with two keratin 5 molecules, a type II keratin. Together they form the cytoskeleton of epithelial cells. Mutations in the genes for these keratins are associated with epidermolysis bullosa simplex. At least one pseudogene has been identified at 17p12-p11.

Gene Name: keratin 14
Synonyms: KRT14, CK-14, EBS3, EBS4, K14, Keratin-14, CK14, Cytokeratin 14, Cytokeratin-14, Keratin 14, NFJ
Target Sequences: NM_000526 NP_000517.2 P02533

Publications (4)

1
Correction of laminin-5 deficiency in human epidermal stem cells by transcriptionally targeted lentiviral vectors. Di Nunzio F, Maruggi G, Ferrari S, Di Iorio E, Poletti V, Garcia M, Del Rio M, De Luca M, Larcher F, Pellegrini G, Mavilio F. Molecular therapy : the journal of the American Society of Gene Therapy. 2008 16:1977-85. (IHC) [PubMed:18813277]
2
Short-course rapamycin treatment preserves airway epithelium and protects against bronchiolitis obliterans. Gillen JR, Zhao Y, Harris DA, LaPar DJ, Kron IL, Lau CL. The Annals of thoracic surgery. 2013 96:464-72. (ICC; Human) [Full Text Article] [PubMed:23806229] [PMC:PMC3886804]
3
Treatment with placenta-derived mesenchymal stem cells mitigates development of bronchiolitis obliterans in a murine model. Zhao Y, Gillen JR, Harris DA, Kron IL, Murphy MP, Lau CL. The Journal of thoracic and cardiovascular surgery. 2014 147:1668-1677. (ICC; Human) [Full Text Article] [PubMed:24199758] [PMC:PMC4073205]
4
Fibroblast growth factor receptor two (FGFR2) regulates uterine epithelial integrity and fertility in mice. Filant J, DeMayo FJ, Pru JK, Lydon JP, Spencer TE. Biology of reproduction. 2014 Jan;90:7. [Full Text Article] [PubMed:24227756] Related Antibodies: LS-B3916.
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KRT14 / CK14 / Cytokeratin 14 ELISA Kit
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KRT14 / CK14 / Cytokeratin 14 ELISA Kit
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0.156 - 10 ng/ml
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).