KRT17 / CK17 / Cytokeratin 17

keratin 17

May play a role in the formation and maintenance of various skin appendages, specifically in determining shape and orientation of hair. May be a marker of basal cell differentiation in complex epithelia and therefore indicative of a certain type of epithelial "stem cells". May act as an autoantigen in the immunopathogenesis of psoriasis, with certain peptide regions being a major target for autoreactive T-cells and hence causing their proliferation. Required for the correct growth of hair follicles, in particular for the persistence of the anagen (growth) state. Modulates the function of TNF-alpha in the specific context of hair cycling. Regulates protein synthesis and epithelial cell growth through binding to the adapter protein SFN and by stimulating Akt/mTOR pathway. Involved in tissue repair.

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Products

Proteins (6)

Type

Recombinant (6)

Target

KRT17 / CK17 / Cytokeratin 17 (6)

Publications

No (6)

Tag

6His, N-terminus (1)

GST (1)

His (2)

His-S (1)

His-SUMO (1)

Species

Bovine (1)

Human (4)

Rat (1)

Source

E. coli (5)

Wheat Germ Extract (1)

Purification

Purified (2)

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Human KRT17 / CK17 / Cytokeratin 17 Protein (Recombinant 6His, N-terminus) (Thr2-Arg432) - LS-G26473

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

50 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Human KRT17 / CK17 / Cytokeratin 17 Protein (Recombinant His-S) (aa252-393) - LS-G14324

Source:

E. coli

Tag:

His-S

Molecular Weight:

22.3 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$2,775; 2 mg/$1,998

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KRT17 / CK17 / Cytokeratin 17 Protein (Recombinant His) (aa84-392) - LS-G14325

Source:

E. coli

Tag:

His

Molecular Weight:

37.1 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Bovine KRT17 / CK17 / Cytokeratin 17 Protein (Recombinant His-SUMO) (Full Length) - LS-G20907

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

64.71 kD

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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Human KRT17 / CK17 / Cytokeratin 17 Protein (Recombinant GST) (Full Length) - LS-G29156

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

73.26 kDa

Price:

10 µg/$479; 25 µg/$670

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Human KRT17 / CK17 / Cytokeratin 17 Protein (Recombinant His) - LS-G2795

Source:

E. coli

Tag:

His

Price:

100 µg/$411; 500 µg/$985; 20 µg/$276

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