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KRT20 / CK20 / Cytokeratin 20 is a member of the keratin family. The keratins are intermediate filament proteins responsible for the structural integrity of epithelial cells and are subdivided into cytokeratins and hair keratins. The type I cytokeratins consist of acidic proteins which are arranged in pairs of heterotypic keratin chains. This cytokeratin is a major cellular protein of mature enterocytes and goblet cells and is specifically expressed in the gastric and intestinal mucosa. The type I cytokeratin genes are clustered in a region of chromosome 17q12-q21.
Gene Name: | keratin 20 |
Family/Subfamily: | Keratin , not assigned-Keratin |
Synonyms: | KRT20, Cytokeratin-20, Cytokeratin 20, CK20, K20, Keratin 20, Keratin-20, KRT21, CK-20, Protein IT |
Target Sequences: | X73502 CAA51914.1 P35900 |
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