KRT6A / CK6A / Cytokeratin 6A

keratin 6A

The protein encoded by this gene is a member of the keratin gene family. The type II cytokeratins consist of basic or neutral proteins which are arranged in pairs of heterotypic keratin chains coexpressed during differentiation of simple and stratified epithelial tissues. As many as six of this type II cytokeratin (KRT6) have been identified; the multiplicity of the genes is attributed to successive gene duplication events. The genes are expressed with family members KRT16 and/or KRT17 in the filiform papillae of the tongue, the stratified epithelial lining of oral mucosa and esophagus, the outer root sheath of hair follicles, and the glandular epithelia. This KRT6 gene in particular encodes the most abundant isoform. Mutations in these genes have been associated with pachyonychia congenita. In addition, peptides from the C-terminal region of the protein have antimicrobial activity against bacterial pathogens. The type II cytokeratins are clustered in a region of chromosome 12q12-q13.

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Proteins (10)

Type

Over-Expression Lysate (2)

Recombinant (8)

Target

KRT6A / CK6A / Cytokeratin 6A (10)

Publications

No (10)

Tag

6His, N-terminus (1)

GST (2)

GST, N-terminus (1)

His (2)

His, N-Terminal (1)

His-S (1)

Myc-DDK (Flag) (2)

Species

Human (8)

Rat (1)

Source

293T Cells (1)

E. coli (6)

HEK 293 Cells (1)

Wheat Germ Extract (2)

Purification

Purified (3)

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Human KRT6A / CK6A / Cytokeratin 6A Protein (Recombinant His) (Full Length) - LS-G20910

Source:

E. coli

Tag:

His

Molecular Weight:

64 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human KRT6A / CK6A / Cytokeratin 6A Protein (Recombinant GST, N-terminus) (aa2-564) - LS-G57533

Source:

E. coli

Tag:

GST, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human KRT6A / CK6A / Cytokeratin 6A Protein (Recombinant GST) (Full Length) - LS-G29145

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

87.78 kDa

Price:

10 µg/$479; 25 µg/$670

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Human KRT6A / CK6A / Cytokeratin 6A Protein (Recombinant GST) (Full Length) - LS-G29150

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

86.4 kDa

Price:

2 µg/$439

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Human KRT6A / CK6A / Cytokeratin 6A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88713

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.9 kDa

Price:

20 µg/$150

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KRT6A / CK6A / Cytokeratin 6A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G115895

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

59.9 kDa

Price:

100 µg/$494

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Human KRT6A / CK6A / Cytokeratin 6A Protein (Recombinant His, N-Terminal) - LS-G143939

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

60 kDa

Price:

50 µg/$419

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Human KRT6A / CK6A / Cytokeratin 6A Protein (Recombinant 6His, N-terminus) (Ala2-His564) - LS-G26510

Source:

E. coli

Tag:

6His, N-terminus

Molecular Weight:

62 kDa

Price:

10 µg/$265; 50 µg/$315; 100 µg/$365

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Human KRT6A / CK6A / Cytokeratin 6A Protein (Recombinant His-S) (aa163-468) - LS-G15232

Source:

E. coli

Tag:

His-S

Molecular Weight:

41.3 kDa

Price:

10 µg/$271; 50 µg/$382; 100 µg/$610; 200 µg/$762; 1 mg/$1,817; 500 µg/$1,378; 5 mg/$3,041

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KRT6A / CK6A / Cytokeratin 6A Protein (Recombinant His) (aa323-461) - LS-G15230

Source:

E. coli

Tag:

His

Molecular Weight:

17.5 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$3,361

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