LCAT

lecithin-cholesterol acyltransferase

Central enzyme in the extracellular metabolism of plasma lipoproteins. Synthesized mainly in the liver and secreted into plasma where it converts cholesterol and phosphatidylcholines (lecithins) to cholesteryl esters and lysophosphatidylcholines on the surface of high and low density lipoproteins (HDLs and LDLs). The cholesterol ester is then transported back to the liver. Has a preference for plasma 16:0-18:2 or 18:O-18:2 phosphatidylcholines. Also produced in the brain by primary astrocytes, and esterifies free cholesterol on nascent APOE-containing lipoproteins secreted from glia and influences cerebral spinal fluid (CSF) APOE- and APOA1 levels. Together with APOE and the cholesterol transporter ABCA1, plays a key role in the maturation of glial-derived, nascent lipoproteins. Required for remodeling high-density lipoprotein particles into their spherical forms.

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Products

Proteins (17)

Type

Native (1)

Over-Expression Lysate (2)

Recombinant (14)

Target

LCAT (17)

Application

SDS-PAGE (1)

Publications

No (17)

Tag

6His, C-terminus (2)

GST (1)

GST, N-terminus (1)

His (7)

His, N-Terminal (2)

His,C-terminus (1)

His-T7 (1)

Myc-DDK (Flag) (2)

Species

Human (11)

Mouse (3)

Rat (2)

Source

293T Cells (1)

E. coli (9)

HEK 293 Cells (2)

Human Cells (1)

Mammalian Cells (1)

Mouse (1)

Wheat Germ Extract (2)

Purification

Purified (4)

Low Endotoxin Level

Low endotoxin level (3)

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Human LCAT Protein (Recombinant His,C-terminus) (Met1-Glu440) - LS-G51046

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human LCAT consists 427 amino acids and predicts a molecular mass of 48.5 kDa.

Price:

100 µg/$403

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Human LCAT Protein (Recombinant 6His, C-terminus) (Phe25-Glu440) - LS-G39345

Source:

Human Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

48.1kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,585; 1 mg/$2,157

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Mouse LCAT Protein (Recombinant His) (aa41-210) - LS-G16011

Source:

E. coli

Tag:

His

Molecular Weight:

20.9 kDa

Price:

10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298

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Human LCAT Protein (Recombinant GST, N-terminus) (aa98-197) - LS-G59105

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human LCAT Protein (Recombinant His, N-Terminal) - LS-G144258

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

47 kDa

Price:

50 µg/$419

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Human LCAT Protein (Recombinant GST) (Full Length) - LS-G29179

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

76 kDa

Price:

10 µg/$479; 25 µg/$670

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Human LCAT Protein (Recombinant His) (aa25-433) - LS-G22535

Source:

E. coli

Tag:

His

Molecular Weight:

51.2 kD

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human LCAT Protein (Recombinant His-T7) (aa41-210) - LS-G25996

Source:

E. coli

Tag:

His-T7

Molecular Weight:

23.0 kDa

Price:

10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090

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Human LCAT Protein (Recombinant 6His, C-terminus) (Phe25-Glu440) - LS-G140256

Source:

Mammalian Cells

Tag:

6His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

48.1 kDa

Price:

10 µg/$317; 50 µg/$524

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Human LCAT Protein (Recombinant His) - LS-G2115

Source:

E. coli

Tag:

His

Price:

100 µg/$361; 500 µg/$739; 20 µg/$261

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LCAT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G98971

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.58 kDa

Price:

100 µg/$494

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Human LCAT Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G77993

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

49.58 kDa

Price:

20 µg/$150

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Mouse LCAT Protein (Recombinant His) (aa290-432) - LS-G16010

Source:

E. coli

Tag:

His

Molecular Weight:

17.9 kDa

Price:

10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298

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Rat LCAT Protein (Recombinant His) (aa290-434) - LS-G16013

Source:

E. coli

Tag:

His

Molecular Weight:

17.7 kDa

Price:

10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298

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Rat LCAT Protein (Recombinant His) (aa41-210) - LS-G16012

Source:

E. coli

Tag:

His

Molecular Weight:

21.0 kDa

Price:

10 µg/$288; 50 µg/$487; 100 µg/$780; 200 µg/$972; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298

Select

Human LCAT Protein (Recombinant His) (aa290-433) - LS-G16008

Source:

E. coli

Tag:

His

Molecular Weight:

17.7 kDa

Price:

10 µg/$283; 50 µg/$452; 100 µg/$725; 200 µg/$905; 1 mg/$2,020; 500 µg/$1,558; 5 mg/$3,165; 2 mg/$2,209

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Mouse LCAT Protein (Native His, N-Terminal) - LS-G133753

Source:

Mouse

Tag:

His, N-Terminal

Molecular Weight:

22kDa

Price:

10 µg/$339; 50 µg/$802; 200 µg/$1,430; 100 µg/$1,214; 1 mg/$2,728; 500 µg/$2,223; 5 mg/$5,601; 2 mg/$2,988

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