LGR6

leucine-rich repeat containing G protein-coupled receptor 6

Receptor for R-spondins that potentiates the canonical Wnt signaling pathway and acts as a marker of multipotent stem cells in the epidermis. Upon binding to R-spondins (RSPO1, RSPO2, RSPO3 or RSPO4), associates with phosphorylated LRP6 and frizzled receptors that are activated by extracellular Wnt receptors, triggering the canonical Wnt signaling pathway to increase expression of target genes. In contrast to classical G-protein coupled receptors, does not activate heterotrimeric G-proteins to transduce the signal. May act as a tumor suppressor.

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Products

Antibodies (18)

Proteins (6)

Type

Over-Expression Lysate (4)

Primary (18)

Recombinant (2)

Target

LGR6 (24)

Reactivity

Human (18)

Mouse (2)

Rat (2)

Application

IHC (7)

IHC-P (3)

WB (12)

ELISA (4)

IF (6)

Peptide-ELISA (2)

Host

rabbit (16)

mouse (2)

Product Group

GPCR Database Antibodies (2)

IHCPlus (1)

PathPlus Neuro (1)

Isotype

IgG (12)

IgG1 (2)

Clonality

monoclonal mc (2)

polyclonal pc (16)

Clone

OTI2A3 (2)

Format

Biotin Conjugated (1)

Carrier-free (1)

FITC Conjugated (1)

HRP Conjugated (1)

Unconjugated (15)

Epitope

Internal (2)

440-520 aa, Internal (1)

N-terminal extracellular domain (1)

aa25-250 (1)

aa471-520 (1)

Publications

No (23)

Yes (1)

Tag

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (4)

Species

Human (4)

Source

293T Cells (2)

HEK 293 Cells (2)

Wheat Germ Extract (2)

Purification

Purified (1)

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PathPlus™ LGR6 Antibody (N-terminal extracellular domain) LS-A442

Neuroscience

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(5.0) Rating

(1) Publication(s)

Antibody:

LGR6 Rabbit anti-Human Polyclonal (N-terminal extracellular domain) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$440

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IHC-plus™ LGR6 Antibody (Internal) LS-A621

Fast Shipping

(4.0) Rating

Antibody:

LGR6 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

IHC, IHC-P

Format:

Unconjugated

Price:

50 µg/$460

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LGR6 Antibody (aa471-520) LS-C120734

Antibody:

LGR6 Rabbit anti-Human Polyclonal (aa471-520) Antibody

Reactivity:

Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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LGR6 Antibody LS-C673475

Antibody:

LGR6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µg/$294; 100 µg/$360

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LGR6 Antibody (HRP) LS-C673477

Antibody:

LGR6 Rabbit anti-Human Polyclonal (HRP) Antibody

Reactivity:

Human

Format:

HRP Conjugated

Price:

50 µg/$294; 100 µg/$360

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LGR6 Antibody (Biotin) LS-C673479

Antibody:

LGR6 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Human

Format:

Biotin Conjugated

Price:

50 µg/$294; 100 µg/$360

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LGR6 Antibody (FITC) LS-C673478

Antibody:

LGR6 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Human

Format:

FITC Conjugated

Price:

50 µg/$294; 100 µg/$360

• Unconjugated
• HRP
• Biotin
• FITC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC

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LGR6 Antibody (440-520 aa, Internal) LS-C384337

Antibody:

LGR6 Rabbit anti-Human Polyclonal (440-520 aa, Internal) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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LGR6 Antibody (clone OTI2A3) LS-C173950

Antibody:

LGR6 Mouse anti-Human Monoclonal (OTI2A3) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated

Price:

100 µl/$434

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LGR6 Antibody (aa25-250, clone OTI2A3, Carrier-free) LS-C787163

Antibody:

LGR6 Mouse anti-Human Monoclonal (aa25-250) (Carrier-free) (OTI2A3) Antibody

Reactivity:

Human

Applications:

IF, WB

Format:

Unconjugated, Carrier-free

Price:

100 µg/$511

• Unconjugated
• Unconjugated, Carrier-free

• Unconjugated
• Unconjugated, Carrier-free

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LGR6 Antibody LS-C153479

Antibody:

LGR6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

200 µl/$468

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LGR6 Antibody LS-C349103

Antibody:

LGR6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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LGR6 Antibody LS-C751632

Antibody:

LGR6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$331

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LGR6 Antibody LS-C825087

Antibody:

LGR6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$357

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LGR6 Antibody LS-C809455

Antibody:

LGR6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Human

Applications:

IF, Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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LGR6 Antibody LS-C834433

Antibody:

LGR6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$331; 120 µl/$403; 200 µl/$529

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LGR6 Antibody (Internal) LS-C358792

Antibody:

LGR6 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

30 µl/$255; 100 µl/$299; 200 µl/$351

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LGR6 Antibody LS-C749186

Antibody:

LGR6 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

20 µl/$275; 100 µl/$389

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Human LGR6 Protein (Recombinant GST, N-terminus) (aa403-496) - LS-G63034

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human LGR6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88803

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

104.1 kDa

Price:

20 µg/$215

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Human LGR6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G88805

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99.1 kDa

Price:

20 µg/$215

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LGR6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G121314

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

104.1 kDa

Price:

100 µg/$710

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LGR6 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G127166

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

99.1 kDa

Price:

100 µg/$710

Select

Human LGR6 Protein (Recombinant GST) (Full Length) - LS-G34861

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

115.7 kDa

Price:

10 µg/$479; 25 µg/$670

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