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LPAR2 / EDG4

lysophosphatidic acid receptor 2

Receptor for lysophosphatidic acid (LPA), a mediator of diverse cellular activities. Seems to be coupled to the G(i)/G(o), G(12)/G(13), and G(q) families of heteromeric G proteins. Plays a key role in phospholipase C-beta (PLC-beta) signaling pathway. Stimulates phospholipase C (PLC) activity in a manner that is independent of RALA activation.

Gene Name: lysophosphatidic acid receptor 2
Family/Subfamily: GPCR , Lysophospholipid/Lysosphingolipid
Synonyms: LPAR2, EDG4, LPA-2, LPA receptor 2, LPA receptor EDG4, LPA2, EDG-4
Target Sequences: NM_004720 NP_004711.2 Q9HBW0

Publications (2)

1
Nm23-H1 suppresses tumor cell motility by down-regulating the lysophosphatidic acid receptor EDG2. Horak CE, Lee JH, Elkahloun AG, Boissan M, Dumont S, Maga TK, Arnaud-Dabernat S, Palmieri D, Stetler-Stevenson WG, Lacombe ML, Meltzer PS, Steeg PS. Cancer research. 2007 67:7238-46. (WB; Human) [PubMed:17671192] Related Antibodies: LS-C100388.
2
Elevated plasma levels of lysophosphatidic acid and aberrant expression of lysophosphatidic acid receptors in adenomyosis. Yang B, Wang L, Wan X, Li Y, Yu X, Qin Y, Luo Y, Wang F, Huang O. BMC women's health. 2017 November;17:118. (Human) [Full Text Article] [PubMed:29178922] [PMC:PMC5702234] Related Antibodies: LS-B512.

☰ Filters
Antibodies (22)
Proteins (4)
Over-Expression Lysate (2)
Primary (22)
Recombinant (2)
LPAR2 / EDG4 (26)
Human (21)
Mouse (6)
Rat (1)
Monkey (1)
IHC (10)
IHC-P (3)
WB (19)
ELISA (11)
ICC (1)
IF (7)
Peptide-ELISA (5)
rabbit (21)
sheep (1)
Product Group
GPCR Database Antibodies (1)
IHCPlus (1)
PathPlus Cancer (1)
IgG (18)
polyclonal pc (22)
APC Conjugated (1)
Azide-free (1)
Biotin Conjugated (1)
FITC Conjugated (1)
HRP Conjugated (1)
PE Conjugated (1)
Unconjugated (17)
aa3-32 (7)
250-330 aa, C-terminal (1)
Cytoplasmic Domain (1)
Gln330 (1)
aa1-33 (1)
aa18-32 (1)
aa261-310 (1)
aa271-320 (1)
aa281-330 (1)
aa290-339 (1)
No (24)
Yes (2)
GST (2)
Myc-DDK (Flag) (2)
Human (3)
293T Cells (1)
HEK 293 Cells (1)
Wheat Germ Extract (2)
Purified (2)
LPAR2 / EDG4 Antibody - Anti-LPAR2 / EDG4 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (aa18-32) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
LPAR2 / EDG4 Antibody - Immunohistochemistry of paraffin-embedded Human gastric cancer using LPAR2 Polyclonal Antibody at dilution of 1:40.
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
LPAR2 / EDG4 Antibody - Formalin-fixed and paraffin-embedded human cancer tissue reacted with the primary antibody, which was peroxidase-conjugated to the secondary antibody, followed by AEC staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated. BC = breast carcinoma; HC = hepatocarcinoma.
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (aa3-32) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (aa3-32) Antibody
Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (aa3-32) (Biotin) Antibody
Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (aa3-32) (FITC) Antibody
Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (aa3-32) (APC) Antibody
Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (aa3-32) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (aa3-32) (PE) Antibody
Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
LPAR2 / EDG4 Antibody - Immunofluorescence analysis of LOVO cells, using EDG4 Antibody. The picture on the right is blocked with the synthesized peptide.
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (aa290-339) Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
LPAR2 / EDG4 Antibody - Human Brain, Cortex: Formalin-Fixed, Paraffin-Embedded (FFPE)
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Cancer
Fast Shipping
LPAR2 / EDG4 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
ICC, IHC, IHC-P
Unconjugated
50 µg/$460
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (250-330 aa, C-terminal) Antibody
Mouse, Human, Monkey
ELISA, IF, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
LPAR2 / EDG4 Antibody - Immunofluorescence analysis of MCF7 cells, using EDG4 Antibody. The picture on the right is blocked with the synthesized peptide.
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (aa271-320) Antibody
Mouse, Human
IF, Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
LPAR2 / EDG4 Antibody - Western blot of EDG-4 (Q330) pAb in extracts from COLO205 cells.
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (Gln330) Antibody
Mouse, Rat, Human
IF, WB
Unconjugated
50 µl/$321; 100 µl/$403
LPAR2 / EDG4 Antibody - Peptide - + Immunofluorescence analysis of MCF-7 cells, using EDG4 antibody.
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
ELISA, IF, WB
Unconjugated
100 µg/$357
LPAR2 / EDG4 Antibody - Peptide - + Immunofluorescence analysis of LOVO cells, using EDG4 antibody.
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$357
LPAR2 / EDG4 Antibody - Staining COLO205 cells by IF/ICC. The samples were fixed with PFA and permeabilized in 0.1% Triton X-100, then blocked in 10% serum for 45 min at 25°C. The primary antibody was diluted at 1:200 and incubated with the sample for 1 hour at 37°C. An Alexa Fluor 594 conjugated goat anti-rabbit IgG (H+L) Ab, diluted at 1/600, was used as the secondary antibody.
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal Antibody
Human
IF, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
LPAR2 / EDG4 Antibody - Western blot analysis of the lysates from COLO205 cells using EDG4 antibody.
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (aa281-330) Antibody
Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
LPAR2 / EDG4 Antibody - Western blot analysis of the lysates from K562 cells using EDG4 antibody.
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal (aa261-310) Antibody
Mouse, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
60 µl/$331; 120 µl/$403; 200 µl/$529
LPAR2 / EDG4 Antibody - Western blot analysis of extracts of HL-60 cells, using LPAR2 antibody at 1:1000 dilution. The secondary antibody used was an HRP Goat Anti-Rabbit IgG (H+L) at 1:10000 dilution. Lysates were loaded 25ug per lane and 3% nonfat dry milk in TBST was used for blocking. An ECL Kit was used for detection and the exposure time was 90s.
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LPAR2 / EDG4 Rabbit anti-Human Polyclonal Antibody
Human
WB
Unconjugated
20 µl/$275; 100 µl/$389
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LPAR2 / EDG4 Sheep anti-Human Polyclonal (aa1-33) Antibody
Human
WB
Unconjugated
100 µg/$896
LPAR2 / EDG4 Protein - 12.5% SDS-PAGE of human EDG4 stained with Coomassie Blue
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Wheat Germ Extract
GST
64.35 kDa
2 µg/$439
LPAR2 / EDG4 Protein - 12.5% SDS-PAGE of human EDG4 stained with Coomassie Blue
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Wheat Germ Extract
GST
65.5 kDa
2 µg/$439
LPAR2 / EDG4 Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
38.9 kDa
20 µg/$150
Viewing 1-25 of 26 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).