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LSP1 is an intracellular F-actin binding protein. The protein is expressed in lymphocytes, neutrophils, macrophages, and endothelium and may regulate neutrophil motility, adhesion to fibrinogen matrix proteins, and transendothelial migration. Alternative splicing results in multiple transcript variants encoding different isoforms.
Gene Name: | lymphocyte-specific protein 1 |
Synonyms: | LSP1, 47 kDa actin-binding protein, 47 kDa actin binding protein, 52 kDa phosphoprotein, Leukocyte-specific protein 1, Lymphocyte-specific protein 1, Pp52, WP34 |
Target Sequences: | NM_002339 NP_002330.1 P33241 |
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