MMP2

matrix metallopeptidase 2 (gelatinase A, 72kDa gelatinase, 72kDa type IV collagenase)

Ubiquitinous metalloproteinase that is involved in diverse functions such as remodeling of the vasculature, angiogenesis, tissue repair, tumor invasion, inflammation, and atherosclerotic plaque rupture. As well as degrading extracellular matrix proteins, can also act on several nonmatrix proteins such as big endothelial 1 and beta-type CGRP promoting vasoconstriction. Also cleaves KISS at a Gly-|-Leu bond. Appears to have a role in myocardial cell death pathways. Contributes to myocardial oxidative stress by regulating the activity of GSK3beta. Cleaves GSK3beta in vitro. Involved in the formation of the fibrovascular tissues in association with MMP14.PEX, the C-terminal non-catalytic fragment of MMP2, posseses anti-angiogenic and anti-tumor properties and inhibits cell migration and cell adhesion to FGF2 and vitronectin. Ligand for integrinv/beta3 on the surface of blood vessels.Isoform 2: Mediates the proteolysis of CHUK/IKKA and initiates a primary innate immune response by inducing mitochondrial-nuclear stress signaling with activation of the pro-inflammatory NF-kappaB, NFAT and IRF transcriptional pathways.

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Products

ELISA Kits (52)

Type

Cell-Based (1)

Competitive EIA (2)

Custom (3)

Sandwich (39)

Sandwich CLIA (7)

Target

MMP2 (52)

Reactivity

Human (12)

Mouse (13)

Rat (12)

Canine (1)

Chicken (2)

Guinea pig (1)

Horse (2)

Monkey (2)

Pig (4)

Rabbit (4)

Format

12 x 8-Well Microstrips (2)

96-Well Microplate (12)

96-Well Strip Plate (38)

Publications

No (52)

Sample Type

Adherent Cell Cultures (1)

Cell Culture Supernatants (16)

Cell Lysates (4)

Plasma (46)

Serum (46)

Tissue Homogenates (20)

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Human MMP2 (Sandwich ELISA) ELISA Kit - LS-F2512

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

625 - 40000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

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Pig MMP2 (Sandwich ELISA) ELISA Kit - LS-F7320

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Pig

Range:

31.2 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$779

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Rat MMP2 (Sandwich ELISA) ELISA Kit - LS-F24966

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$624

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Human MMP2 (Sandwich ELISA) ELISA Kit - LS-F24619

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

312.5 - 20000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$582

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Mouse MMP2 (Sandwich ELISA) ELISA Kit - LS-F21409

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

0.16 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$528

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Mouse MMP2 (Sandwich ELISA) ELISA Kit - LS-F2513

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

625 - 40000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

Select

Human MMP2 (Sandwich ELISA) ELISA Kit - LS-F4963

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$537

Select

Mouse MMP2 (Sandwich ELISA) ELISA Kit - LS-F53253

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

15.6 - 1000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$744

Select

Guinea pig MMP2 (Sandwich ELISA) ELISA Kit - LS-F45562

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Guinea pig

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$565

Select

Human MMP2 (Sandwich ELISA) ELISA Kit - LS-F157

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

3.277 - 320 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

Select

Mouse/Human/Rat MMP2 (Cell-Based ELISA) ELISA Kit - LS-F2161

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

Select

Rat MMP2 (Sandwich ELISA) ELISA Kit - LS-F2602

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

156 - 10000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$699

Select

Mouse MMP2 (Sandwich ELISA) ELISA Kit - LS-F276

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Mouse

Range:

27.43 - 6667 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Plasma, Serum

Price:

1 Plate/$534

Select

Rat MMP2 (Sandwich ELISA) ELISA Kit - LS-F5517

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$715

Select

Mouse MMP2 (Sandwich ELISA) ELISA Kit - LS-F4964

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$782

Select

Horse MMP2 (Sandwich ELISA) ELISA Kit - LS-F9851

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Horse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$795

Select

Chicken MMP2 (Custom ELISA) ELISA Kit - LS-F13740

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Chicken

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Mouse MMP2 (Custom ELISA) ELISA Kit - LS-F13741

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$585

Select

Bovine MMP2 (Custom ELISA) ELISA Kit - LS-F13742

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

Select

Rat MMP2 (Sandwich ELISA) ELISA Kit - LS-F13328

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

Select

Human MMP2 (Sandwich ELISA) ELISA Kit - LS-F13327

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.312 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$585

Select

Horse MMP2 (Sandwich ELISA) ELISA Kit - LS-F39136

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Horse

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$760

Select

Canine MMP2 (Sandwich ELISA) ELISA Kit - LS-F31833

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Canine

Range:

31.25 - 2000 pg/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse MMP2 (Sandwich ELISA) ELISA Kit - LS-F32056

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse MMP2 (CLIA) ELISA Kit - LS-F30849

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse

Range:

31.25 - 2000 pg/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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