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MOG

myelin oligodendrocyte glycoprotein

MOG is a membrane protein expressed on the oligodendrocyte cell surface and the outermost surface of myelin sheaths. Due to this localization, it is a primary target antigen involved in immune-mediated demyelination. This protein may be involved in completion and maintenance of the myelin sheath and in cell-cell communication. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: myelin oligodendrocyte glycoprotein
Family/Subfamily: Immunoglobulin , not assigned-Immunoglobulin
Synonyms: MOG, NRCLP7, MOGIG2, MOG alpha-5, MOG Ig-AluB
Target Sequences: NM_002433 NP_002424.3 Q16653

Publications (1)

1
The formation of tau pore-like structures is prevalent and cell specific: possible implications for the disease phenotypes. Lasagna-Reeves CA, Sengupta U, Castillo-Carranza D, Gerson JE, Guerrero-Munoz M, Troncoso JC, Jackson GR, Kayed R. Acta neuropathologica communications. 2014 2:56. (IHC; Mouse) [Full Text Article] [PubMed:24887264] [PMC:PMC4231072]

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Products
Proteins (15)
Over-Expression Lysate (2)
Recombinant (12)
MOG (15)
No (15)
6His, C-terminus (4)
GST (1)
His (3)
His, N-terminus (1)
His,C-terminus (1)
His-S (1)
Myc-DDK (Flag) (3)
Bovine (1)
Human (10)
Mouse (2)
Rat (1)
293T Cells (1)
E. coli (9)
HEK 293 Cells (2)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (5)
Low endotoxin level (4)
MOG Protein - 12.5% SDS-PAGE of human MOG stained with Coomassie Blue
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Wheat Germ Extract
GST
58.19 kDa
2 µg/$439
MOG Protein - Recombinant Myelin Oligodendrocyte Glycoprotein By SDS-PAGE
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E. coli
His, N-terminus
15.7 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Select
E. coli
His
15.8 kDa
10 µg/$274; 50 µg/$400; 100 µg/$637; 200 µg/$797; 1 mg/$1,870; 500 µg/$1,424; 5 mg/$2,832; 2 mg/$2,053
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15.2kD
10 µg/$262; 50 µg/$365; 500 µg/$1,585; 1 mg/$2,157
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15.31kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585
MOG Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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293T Cells
Myc-DDK (Flag)
25.1 kDa
20 µg/$150
MOG Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
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HEK 293 Cells
Myc-DDK (Flag)
25.1 kDa
100 µg/$494
MOG Protein - Purified recombinant protein MOG was analyzed by SDS-PAGE gel and Coomassie Blue Staining
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HEK 293 Cells
Myc-DDK (Flag)
25.1 kDa
20 µg/$1,107
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15.3 kDa
10 µg/$288; 50 µg/$436
Select
E. coli
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
15.2 kDa
10 µg/$262; 50 µg/$361
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E. coli
None
15.2 kDa
10 µg/$329; 50 µg/$412; 1000 µg/$2,111
Select
E. coli
His
18.0 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
Select
E. coli
His
16 kDa
100 µg/$843
Select
E. coli
His,C-terminus
15 kDa
50 µg/$721; 500 µg/$4,249
MOG Protein - Recombinant Myelin Oligodendrocyte Glycoprotein By SDS-PAGE
Select
E. coli
His-S
19.5 kDa
10 µg/$267; 50 µg/$352; 100 µg/$562; 200 µg/$702; 1 mg/$1,723; 500 µg/$1,298; 5 mg/$2,673; 2 mg/$1,900
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).