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The activation peptides of aspartic proteinases plays role as inhibitors of the active site. These peptide segments, or pro-parts, are deemed important for correct folding, targeting, and control of the activation of aspartic proteinase zymogens. The pronapsin A gene is expressed predominantly in lung and kidney. Its translation product is predicted to be a fully functional, glycosylated aspartic proteinase precursor containing an RGD motif and an additional 18 residues at its C-terminus.
Gene Name: | napsin A aspartic peptidase |
Family/Subfamily: | Protease , Aspartic A1 |
Synonyms: | NAPSA, Asp 4, ASP4, Aspartyl protease 4, Kdap, NAP1, Napsin A aspartic peptidase, Napsin-1, KAP, TA01/TA02, Napsin A, Napsin-A, SNAPA, NAP 1, Pronapsin A |
Target Sequences: | NM_004851 NP_004842.1 O96009 |
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