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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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NOS2 / iNOS

nitric oxide synthase 2, inducible

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.

Gene Name: nitric oxide synthase 2, inducible
Synonyms: NOS2, Hepatocyte NOS, HEP-NOS, Inducible NOS, NOS, type II, NOS type II, Inducible NO synthase, NOS2A, INOS, NOS
Target Sequences: NM_000625 NP_000616.3 P35228

Publications (8)

1
Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms. Yang A, Herter-Sprie G, Zhang H, Lin EY, Biancur D, Wang X, Deng J, Hai J, Yang S, Wong KK, Kimmelman AC. Cancer discovery. 2018 March;8:276-287. [Full Text Article] [PubMed:29317452] [PMC:PMC5835190]
2
Acquisition of heroin conditioned immunosuppression requires IL-1 signaling in the dorsal hippocampus. Lebonville CL, Jones ME, Hutson LW, Cooper LB, Fuchs RA, Lysle DT. Brain, behavior, and immunity. 2016 August;56:325-34. [Full Text Article] [PubMed:27072068] [PMC:PMC4917416]
3
Interleukin-1 signaling in the basolateral amygdala is necessary for heroin-conditioned immunosuppression. Hutson LW, Lebonville CL, Jones ME, Fuchs RA, Lysle DT. Brain, behavior, and immunity. 2017 May;62:171-179. [Full Text Article] [PubMed:28131792] [PMC:PMC5828772]
4
Testosterone regulates thyroid cancer progression by modifying tumor suppressor genes and tumor immunity. Lisa J Zhang, Yin Xiong, Naris Nilubol, Mei He, Swaroop Bommareddi, Xuguang Zhu, Li Jia, Zhen Xiao, Jeong-Won Park, Xia Xu, Dhaval Patel, Mark C Willingham, Sheue-Yann Cheng, Electron Kebebew. Carcinogenesis. 2015 April;36:420-8. [Full Text Article] [PubMed:25576159] [PMC:PMC4392603] Related Antibodies: LS-C15859.
5
rhBMP2 alone does not induce macrophage polarization towards an increased inflammatory response. Emily L Durham, Rajiv Kishinchand, Zachary J Grey, James J Cray. Molecular immunology. 2020 January;117:94-100. [Full Text Article] [PubMed:31759326] [PMC:PMC6931256]
6
Mystery Solved: Why Smoke Extract Worsens Disease in Smokers with Crohn's Disease and Not Ulcerative Colitis? Gut MAP!. Dania AlQasrawi, Latifa S Abdelli, Saleh A Naser. Microorganisms. 2020 May;8:666. [Full Text Article] [PubMed:32370298] [PMC:PMC7284734]
7
T-cell derived acetylcholine aids host defenses during enteric bacterial infection with Citrobacter rodentium. Valerie T Ramirez, Dayn R Godinez, Ingrid Brust-Mascher, Eric B Nonnecke, Patricia A Castillo, Mariana Barboza Gardner , Diane Tu, Jessica A Sladek, Elaine N Miller, Carlito B Lebrilla, Charles L Bevins, Melanie G Gareau, Colin Reardon. PLoS pathogens. 2019 Apr;15:e1007719. [Full Text Article] [PubMed:30973939] [PMC:PMC6478367] Related Antibodies: LS-B10049.
8
Anti-inflammatory properties of a proprietary bromelain extract (Bromeyal™) after in vitro simulated gastrointestinal digestion. Roberta Bottega, Ilaria Persico, Francesco De Seta, Federico Romano, Giovanni Di Lorenzo. International journal of immunopathology and pharmacology. 2021 August;35:20587384211034686. [Full Text Article] [PubMed:34387509] [PMC:PMC8366142]
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NOS2 / iNOS Antibody - Anti-NOS2 / iNOS antibody IHC staining of human skeletal muscle. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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Cancer
NOS2 / iNOS Mouse anti-Human Monoclonal (aa997-1058) (4E5) Antibody
Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
50 µg/$460
NOS2 / iNOS Antibody - Immunohistochemical analysis of iNOS staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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NOS2 / iNOS Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
ICC, IF, IHC, IHC-P, WB
Unconjugated
100 µl/$299
NOS2 / iNOS Antibody - Western blot of NOS2 / iNOS antibody.
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NOS2 / iNOS Rabbit anti-Mouse Polyclonal Antibody
Mouse, Mammal
ICC, IP, WB
Unconjugated
1 Each/$431
NOS2 / iNOS Antibody - Immunohistochemical analysis of iNOS staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected with HRP and DAB as chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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NOS2 / iNOS Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Bovine, Rat, Human
IHC, IHC-P, WB
Unconjugated
30 µl/$255; 100 µl/$299; 200 µl/$351
NOS2 / iNOS Antibody - Western blot of recombinant NOS2 / iNOS.  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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NOS2 / iNOS Rabbit anti-Human Polyclonal (aa533-696) (Biotin) Antibody
Human
WB
Biotin Conjugated
100 µl/$308; 200 µl/$350; 500 µl/$489; 1 ml/$558; 2 ml/$749; 5 ml/$1,217
NOS2 / iNOS Antibody - Immunohistochemistry-Paraffin: iNOS Antibody (4E5) - Immunohistochemical analysis of paraffin-embedded breast cancer tissues using iNOS mouse mAb with DAB staining.
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NOS2 / iNOS Mouse anti-Human Monoclonal (4E5) Antibody
Mouse, Human
ELISA, Flo, IHC, IHC-P, WB
Unconjugated
0.1 ml/$386
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$715
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$782
NOS2 / iNOS ELISA Kit
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Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$764
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
NOS2 / iNOS ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Microplate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Microplate
Pig
0.31 - 20 IU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$565
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Microplate
Human
78.1 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates
1 Plate/$731
NOS2 / iNOS Protein - Recombinant Nitric Oxide Synthase 2, Inducible By SDS-PAGE
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E. coli
His, N-Terminal
22.1 kDa
10 µg/$279; 50 µg/$432; 100 µg/$690; 200 µg/$862; 1 mg/$1,962; 500 µg/$1,505; 5 mg/$3,011; 2 mg/$2,148
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NOS2 / iNOS Mouse anti-Human Monoclonal (aa1009-1026) Antibody
Human
ELISA, ICC, IF, WB
Unconjugated
1 ml/$688
NOS2 / iNOS Antibody - Human Liver: Formalin-Fixed, Paraffin-Embedded (FFPE)
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NOS2 / iNOS Rabbit anti-Human Polyclonal (aa830-860) Antibody
Human
Flo, IF, IHC, IHC-P, WB
Unconjugated
200 µl/$460
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NOS2 / iNOS Mouse anti-Human Monoclonal (aa781-798) Antibody
Human
ELISA, ICC, IF, WB
Unconjugated
1 ml/$688
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NOS2 / iNOS Mouse anti-Human Monoclonal (aa25-54) (7C204) Antibody
Human
ELISA, ICC, IF, WB
Unconjugated
100 µl/$618
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NOS2 / iNOS Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$832
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NOS2 / iNOS Rabbit anti-Mouse Polyclonal (C-Terminus) Antibody
Mouse, Rat
ICC, IHC, WB
Unconjugated
50 µl/$786
NOS2 / iNOS Antibody - iNOS Antibody in Immunohistochemistry (IHC)
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NOS2 / iNOS Mouse anti-Human Monoclonal (400000) Antibody
Mouse, Human
Flo, ICC, IF, IHC, WB
Unconjugated
100 µg/$503
Viewing 1-25 of 182 product results



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PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).