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Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
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NOS2 / iNOS

nitric oxide synthase 2, inducible

Produces nitric oxide (NO) which is a messenger molecule with diverse functions throughout the body. In macrophages, NO mediates tumoricidal and bactericidal actions. Also has nitrosylase activity and mediates cysteine S-nitrosylation of cytoplasmic target proteins such COX2.

Gene Name: nitric oxide synthase 2, inducible
Synonyms: NOS2, Hepatocyte NOS, HEP-NOS, Inducible NOS, NOS, type II, NOS type II, Inducible NO synthase, NOS2A, INOS, NOS
Target Sequences: NM_000625 NP_000616.3 P35228

Publications (8)

1
Autophagy Sustains Pancreatic Cancer Growth through Both Cell-Autonomous and Nonautonomous Mechanisms. Yang A, Herter-Sprie G, Zhang H, Lin EY, Biancur D, Wang X, Deng J, Hai J, Yang S, Wong KK, Kimmelman AC. Cancer discovery. 2018 March;8:276-287. [Full Text Article] [PubMed:29317452] [PMC:PMC5835190]
2
Acquisition of heroin conditioned immunosuppression requires IL-1 signaling in the dorsal hippocampus. Lebonville CL, Jones ME, Hutson LW, Cooper LB, Fuchs RA, Lysle DT. Brain, behavior, and immunity. 2016 August;56:325-34. [Full Text Article] [PubMed:27072068] [PMC:PMC4917416]
3
Interleukin-1 signaling in the basolateral amygdala is necessary for heroin-conditioned immunosuppression. Hutson LW, Lebonville CL, Jones ME, Fuchs RA, Lysle DT. Brain, behavior, and immunity. 2017 May;62:171-179. [Full Text Article] [PubMed:28131792] [PMC:PMC5828772]
4
Testosterone regulates thyroid cancer progression by modifying tumor suppressor genes and tumor immunity. Lisa J Zhang, Yin Xiong, Naris Nilubol, Mei He, Swaroop Bommareddi, Xuguang Zhu, Li Jia, Zhen Xiao, Jeong-Won Park, Xia Xu, Dhaval Patel, Mark C Willingham, Sheue-Yann Cheng, Electron Kebebew. Carcinogenesis. 2015 April;36:420-8. [Full Text Article] [PubMed:25576159] [PMC:PMC4392603] Related Antibodies: LS-C15859.
5
rhBMP2 alone does not induce macrophage polarization towards an increased inflammatory response. Emily L Durham, Rajiv Kishinchand, Zachary J Grey, James J Cray. Molecular immunology. 2020 January;117:94-100. [Full Text Article] [PubMed:31759326] [PMC:PMC6931256]
6
Mystery Solved: Why Smoke Extract Worsens Disease in Smokers with Crohn's Disease and Not Ulcerative Colitis? Gut MAP!. Dania AlQasrawi, Latifa S Abdelli, Saleh A Naser. Microorganisms. 2020 May;8:666. [Full Text Article] [PubMed:32370298] [PMC:PMC7284734]
7
T-cell derived acetylcholine aids host defenses during enteric bacterial infection with Citrobacter rodentium. Valerie T Ramirez, Dayn R Godinez, Ingrid Brust-Mascher, Eric B Nonnecke, Patricia A Castillo, Mariana Barboza Gardner , Diane Tu, Jessica A Sladek, Elaine N Miller, Carlito B Lebrilla, Charles L Bevins, Melanie G Gareau, Colin Reardon. PLoS pathogens. 2019 Apr;15:e1007719. [Full Text Article] [PubMed:30973939] [PMC:PMC6478367] Related Antibodies: LS-B10049.
8
Anti-inflammatory properties of a proprietary bromelain extract (Bromeyal™) after in vitro simulated gastrointestinal digestion. Roberta Bottega, Ilaria Persico, Francesco De Seta, Federico Romano, Giovanni Di Lorenzo. International journal of immunopathology and pharmacology. 2021 August;35:20587384211034686. [Full Text Article] [PubMed:34387509] [PMC:PMC8366142]
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NOS2 / iNOS (33)
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NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Strip Plate
Rat
1.56 - 100 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$715
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
1 Plate/$782
NOS2 / iNOS ELISA Kit
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Cell-Based
96-Well Microplate
Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$534
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$764
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$730
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
NOS2 / iNOS ELISA Kit
Select
Sandwich
96-Well Strip Plate
Human
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
NOS2 / iNOS ELISA Kit
Select
Sandwich
96-Well Microplate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Microplate
Pig
0.31 - 20 IU/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$565
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Microplate
Human
78.1 - 5000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates
1 Plate/$731
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Microplate
Mouse
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$528
NOS2 / iNOS ELISA Kit
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Sandwich
96-Well Strip Plate
Rabbit
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$715
NOS2 / iNOS ELISA Kit
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Development Kit
Antibody Pair and Standard
Rat
3.12 - 200 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
500 Wells/$1,254; 1000 Wells/$1,867
NOS2 / iNOS ELISA Kit
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Development Kit
Antibody Pair and Standard
Mouse
0.625 - 40 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Tissue Homogenates
500 Wells/$1,207; 1000 Wells/$1,787
NOS2 / iNOS ELISA Kit
Select
Development Kit
Antibody Pair and Standard
Human
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Cell Lysates, Plasma, Serum, Tissue Homogenates
500 Wells/$1,182; 1000 Wells/$1,747
NOS2 / iNOS ELISA Kit
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Custom
96-Well Strip Plate
Pig
Colorimetric - 450nm (TMB)
1 Plate/$669
NOS2 / iNOS ELISA Kit
Select
Custom
96-Well Strip Plate
Colorimetric - 450nm (TMB)
1 Plate/$669
NOS2 / iNOS ELISA Kit
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Custom
96-Well Strip Plate
Chicken
Colorimetric - 450nm (TMB)
1 Plate/$783
NOS2 / iNOS ELISA Kit
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Custom
96-Well Strip Plate
Dog
Colorimetric - 450nm (TMB)
1 Plate/$783
NOS2 / iNOS ELISA Kit
Select
Sandwich
96-Well Microplate
Rabbit
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$565
NOS2 / iNOS ELISA Kit
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Sandwich CLIA
12 x 8-Well Microstrips
Mouse
62.5 - 4000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
NOS2 / iNOS ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Tissue Homogenates
1 Plate/$579
NOS2 / iNOS ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rabbit
0.313 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
NOS2 / iNOS ELISA Kit
Select
Sandwich
96-Well Strip Plate
Mouse
0.312 - 20 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).