Products
Research Areas
COVID-19
Resources
Login
Quick Order
Cart Cart lightblue
Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order
Contact Us

Location


Corporate Headquarters

Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States

Telephone Numbers



Customer Service: (800) 227-6666 / (650) 697-3600


Contact Us



Additional Contact Details

Login
Registration enables users to use special features of this website, such as past
order histories, retained contact details for faster checkout, review submissions, and special promotions.


Fields marked with a * are required.

Login
Quick Order

NTN1 / Netrin 1

netrin 1

Netrins control guidance of CNS commissural axons and peripheral motor axons. Its association with either DCC or some UNC5 receptors will lead to axon attraction or repulsion, respectively. It also serve as a survival factor via its association with its receptors which prevent the initiation of apoptosis. Involved in tumorigenesis by regulating apoptosis.

Gene Name: netrin 1
Synonyms: NTN1, Netrin 1, Netrin 1, mouse, homolog of, Netrin-1, NTN1L
Target Sequences: NM_004822 NP_004813.2 O95631

Publications (2)

1
Inhibition of colony stimulating factor 1 receptor corrects maternal inflammation-induced microglial and synaptic dysfunction and behavioral abnormalities. Seiko Ikezu , Hana Yeh , Jean-Christophe Delpech , Maya E Woodbury , Alicia A Van Enoo, Zhi Ruan, Sudhir Sivakumaran, Yang You, Carl Holland, Teresa Guillamon-Vivancos, Asuka Yoshii-Kitahara, Mina B Botros, Charlotte Madore, Pin-Hao Chao, Ankita Desani, Solaiappan Manimaran, Srinidhi Venkatesan Kalavai, W Evan Johnson, Oleg Butovsky, Maria Medalla, Jennifer I Luebke, Tsuneya Ikezu. Molecular psychiatry. 2020 February; [Full Text Article] [PubMed:32071385] [PMC:PMC7431382]
2
PMN-derived netrin-1 attenuates cardiac ischemia-reperfusion injury via myeloid ADORA2B signaling. Jiwen Li, Catharina Conrad, Tingting W Mills, Nathaniel K Berg, Boyun Kim, Wei Ruan, Jae W Lee, Xu Zhang, Xiaoyi Yuan, Holger K Eltzschig. The Journal of experimental medicine. 2021 June;218:e20210008. [Full Text Article] [PubMed:33891683] [PMC:PMC8077173] Related Antibodies: LS-C743016.

☰ Filters
Products
Proteins (6)
Recombinant (6)
NTN1 / Netrin 1 (6)
No (6)
DDK (Flag) (1)
GST, N-terminus (1)
His, N-Terminal (1)
His-GST (1)
His-GST, N-terminus (1)
Human IgG1 Fc (1)
Human (4)
Mouse (1)
Rat (1)
E. coli (3)
HEK 293 Cells (2)
Wheat Germ Extract (1)
Purified (1)
Low endotoxin level (2)
NTN1 / Netrin 1 Protein - Recombinant Netrin 1 (Ntn1) by SDS-PAGE
Select
E. coli
His, N-Terminal
55.5kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
NTN1 / Netrin 1 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
Select
Wheat Germ Extract
GST, N-terminus
2 µg/$439
NTN1 / Netrin 1 Protein - Recombinant Netrin 1 By SDS-PAGE
Select
E. coli
His-GST
55.5 kDa
10 µg/$276; 50 µg/$412; 100 µg/$657; 200 µg/$822; 1 mg/$1,905; 500 µg/$1,455; 5 mg/$2,871; 2 mg/$2,090
Select
HEK 293 Cells
DDK (Flag)
Less than 0.01 EU/µg protein (determined by LAL method).
~80kDa (SDS-PAGE)
10 µg/$386
NTN1 / Netrin 1 Protein - Netrin-1 (human):Fc (human) (rec.) triggers a DCC-dependent phosphorylation of ERK1/2. Method: HEK 293 cells (Control) or HEK 293 expressing the netrin-1 receptor DCC were incubated with netrin-1 (human):Fc (human) (rec.) (5 nM) for the indicated time points (shown in minutes). Antibodies against DCC, total ERK1/2 or phospho-ERK1/2 were used and visualized with a chemiluminescence detection system. Picture courtesy of Nicolas Rama, Prof. Patrick Mehlen lab, Centre Leon Berard, Lyon
Select
HEK 293 Cells
Human IgG1 Fc
Less than 0.1 EU/µg protein (determined by LAL method).
~90kDa (SDS-PAGE)
10 µg/$414
NTN1 / Netrin 1 Protein - Recombinant Netrin 1 (Ntn1) by SDS-PAGE
Select
E. coli
His-GST, N-terminus
58kDa
10 µg/$288; 50 µg/$487; 200 µg/$972; 100 µg/$780; 1 mg/$2,109; 500 µg/$1,636; 5 mg/$3,403; 2 mg/$2,298
Viewing 1-6 of 6 product results


Filtered By:
Products: Proteins


If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).