p14ARF / CDKN2A

p14ARF

p14ARF is one of two proteins transcribed from the gene CDKN2A on chromosome 9 locus p21. p14ARF functions in apoptosis, autophagy and more broadly in tumor suppression via its regulation of MDM2 and p53, where loss of p14arf can inhibit p53 and contribute to survival in cancer cells (pmid: 18199527). Because CDKN2A is frequently deleted, mutated or hypermethylated in a broad range of cancers, evaluating p14ARF status via IHC, elisa or assay can be a useful means of examining cell cycle destabilization and the breakdown of apoptosis in a given cancer.

p14ARF / CDKN2A Target Details

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Products

Proteins (4)

Type

Over-Expression Lysate (4)

Target

p14ARF / CDKN2A (4)

Publications

No (4)

Tag

Myc-DDK (Flag) (4)

Species

Human (2)

Source

293T Cells (2)

HEK 293 Cells (2)

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Human p14ARF / CDKN2A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75349

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

20 µg/$150

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p14ARF / CDKN2A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107932

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

100 µg/$494

Select

Human p14ARF / CDKN2A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G75350

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

20 µg/$150

Select

p14ARF / CDKN2A Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G127294

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

17.8 kDa

Price:

100 µg/$494

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