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P2RY6 / P2Y6
pyrimidinergic receptor P2Y, G-protein coupled, 6
P2RY6 / P2Y6 belongs to the family of P2 receptors, which is activated by extracellular nucleotides and subdivided into P2X ligand-gated ion channels and P2Y G-protein coupled receptors. This family has several receptor subtypes with different pharmacological selectivity, which overlaps in some cases, for various adenosine and uridine nucleotides. This receptor, which is a G-protein coupled receptor, is responsive to UDP, partially responsive to UTP and ADP, and not responsive to ATP. It is proposed that this receptor mediates inflammatory responses. Alternative splicing results in multiple transcript variants that encode different protein isoforms.
| Gene Name: | pyrimidinergic receptor P2Y, G-protein coupled, 6 |
| Family/Subfamily: | GPCR , Purinergic |
| Synonyms: | P2RY6, G-coupled nucleotide receptor, p2 purinoceptor, p2y3 receptor, p2Y purinoceptor 6, Purinergic receptor p2y6, p2RY6, p2y3 and chick, p2Y6 receptor, p2Y6, Purinoceptor p2y6 |
| Target Sequences: | NM_004154 NP_004145.1 Q15077 |
Publications (1)
1
Altered purinergic receptor-Ca²? signaling associated with hypoxia-induced epithelial-mesenchymal transition in breast cancer cells. Azimi I, Beilby H, Davis FM, Marcial DL, Kenny PA, Thompson EW, Roberts-Thomson SJ, Monteith GR. Molecular oncology. 2016 January;10:166-78. (Human)
[Full Text Article]
[PubMed:26433470]
[PMC:PMC5528926]
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Antibodies
(19)
Type
Primary
(19)
Target
P2RY6 / P2Y6
(19)
Reactivity
Human
(19)
Mouse
(3)
Rat
(6)
Bat
(3)
Bovine
(4)
Chimpanzee
(3)
Gibbon
(3)
Hamster
(1)
Monkey
(5)
Orangutan
(3)
Pig
(4)
Rabbit
(4)
Application
IHC
(5)
IHC-P
(3)
WB
(17)
ELISA
(9)
ICC
(1)
IF
(1)
IP
(1)
Peptide-ELISA
(1)
Host
rabbit
(19)
Product Group
GPCR Database Antibodies
(2)
PathPlus Neuro
(2)
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IgG
(11)
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polyclonal pc
(19)
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APC Conjugated
(1)
Azide-free
(1)
Biotin Conjugated
(2)
FITC Conjugated
(2)
HRP Conjugated
(2)
PE Conjugated
(1)
Preservative Free
(1)
Unconjugated
(11)
Epitope
aa286-314
(7)
aa109-158
(4)
C-Terminus
(1)
Cytoplasmic Domain
(1)
Publications
No
(19)
Neuroscience
Fast Shipping
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
ICC, IHC, IHC-P
Unconjugated
50 µg/$440
Neuroscience
Fast Shipping
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (Cytoplasmic Domain) Antibody
Rabbit, Bovine, Rat, Hamster, Pig, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa109-158) Antibody
Human
WB
Unconjugated
100 µl/$424
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa109-158) (HRP) Antibody
Rabbit, Bovine, Rat, Pig, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
HRP Conjugated
100 µl/$469
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa109-158) (Biotin) Antibody
Rabbit, Bovine, Rat, Pig, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa109-158) (FITC) Antibody
Rabbit, Bovine, Rat, Pig, Bat, Gibbon, Orangutan, Chimpanzee, Human, Monkey
WB
FITC Conjugated
100 µl/$469
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal Antibody
Human
IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
IHC-P, IP, WB
Unconjugated, Preservative Free
100 µl/$412
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$341
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) (Biotin) Antibody
Human
ELISA, WB
Biotin Conjugated
200 µl/$952
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) (FITC) Antibody
Human
ELISA, WB
FITC Conjugated
200 µl/$952
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) (APC) Antibody
Human
ELISA, WB
APC Conjugated
200 µl/$952
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) (PE) Antibody
Human
ELISA, WB
PE Conjugated
200 µl/$952
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) (Azide-free) (HRP) Antibody
Human
ELISA, WB
HRP Conjugated, Azide-free
200 µl/$952
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
P2RY6 / P2Y6 Rabbit anti-Human Polyclonal (aa286-314) Antibody
Human
WB
Unconjugated
400 µl/$393
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