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PAEL Receptor / GPR37
G protein-coupled receptor 37 (endothelin receptor type B-like)
GPR37 is an Orphan-A GPCR with an unknown ligand. GPR37 was recently identified as the PAEL receptor, a Parkin substrate involved in autosomal recessive juvenile Parkinson's (PDJ) disease. The PAEL receptor becomes unfolded, insoluble, and ubiquitinated when overexpressed, leading to unfolded protein-induced cell death. When the PAEL receptor is ubiquitinated by Parkin, it gets degraded, resulting in the suppression of cell death. The insoluble form of the PAEL receptor accumulates in the brains of PDJ patients and may cause selective neuronal death.
| Gene Name: | G protein-coupled receptor 37 (endothelin receptor type B-like) |
| Family/Subfamily: | GPCR , Orphan-A |
| Synonyms: | GPR37, EDNRBL, ETBR-LP-1, Gpcr/cns1, HET(B)R-LP, Het-b-r-lp, PAELR, Pael receptor |
| Target Sequences: | NM_005302 NP_005293.1 O15354 |
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PAEL Receptor / GPR37
(29)
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Human
(22)
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(1)
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(1)
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(1)
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(1)
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(29)
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(1)
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Neuroscience
Fast Shipping
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
Fast Shipping
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$440
Fast Shipping
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
Fast Shipping
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$440
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (aa97-126) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PAEL Receptor / GPR37 Mouse anti-Human Monoclonal Antibody
Human
Flo
Unconjugated
100 µg/$896
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (aa468-517) Antibody
Human
WB
Unconjugated
100 µl/$424
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (aa468-517) (HRP) Antibody
Xenopus, Chicken, Bovine, Rabbit, Dog, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
WB
HRP Conjugated
100 µl/$469
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (aa468-517) (Biotin) Antibody
Xenopus, Chicken, Bovine, Rabbit, Dog, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
WB
Biotin Conjugated
100 µl/$469
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (aa468-517) (FITC) Antibody
Xenopus, Chicken, Bovine, Rabbit, Dog, Horse, Orangutan, Gibbon, Human, Monkey, Chimpanzee
WB
FITC Conjugated
100 µl/$469
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (aa217-246) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (180-260 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
100 µg/$331
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (aa211-260) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (aa199-248) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
PAEL Receptor / GPR37 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ELISA
Unconjugated, Preservative Free
100 µl/$412
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
Sandwich CLIA
12 x 8-Well Microstrips
Human
31.25 - 2000 pg/ml
Chemiluminescent
Plasma, Serum
1 Plate/$656
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
Sandwich
96-Well Strip Plate
Porcine
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Rabbit
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Chicken
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
Sandwich
96-Well Strip Plate
Guinea pig
62.5 - 4000 pg/ml
Colorimetric - 450nm (TMB)
1 Plate/$656
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product results
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