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PAK7/PAK5
p21 protein (Cdc42/Rac)-activated kinase 7
PAK7 is a serine/threonine protein kinase that plays a role in a variety of different signaling pathways including cytoskeleton regulation, cell migration, proliferation or cell survival. Activation by various effectors including growth factor receptors or active CDC42 and RAC1 results in a conformational change and a subsequent autophosphorylation on several serine and/or threonine residues. Phosphorylates the proto-oncogene RAF1 and stimulates its kinase activity. Promotes cell survival by phosphorylating the BCL2 antagonist of cell death BAD. Phosphorylates CTNND1, probably to regulate cytoskeletal organization and cell morphology. Keeps microtubules stable through MARK2 inhibition and destabilizes the F-actin network leading to the disappearance of stress fibers and focal adhesions.
| Gene Name: | p21 protein (Cdc42/Rac)-activated kinase 7 |
| Family/Subfamily: | Protein Kinase , PAK (STE20) |
| Synonyms: | PAK7/PAK5, p21(CDKN1A)-activated kinase 7, p21CDKN1A-activated kinase 7, PAK7, PAK-7, PAK5, KIAA1264, p21-activated kinase 5, PAK-5, p21-activated kinase 7, Protein kinase PAK5 |
| Target Sequences: | NM_020341 NP_065074.1 Q9P286 |
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PAK7/PAK5 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, ICC, IF, IHC, IHC-P, WB
Unconjugated
0.05 mg/$460
PAK7/PAK5 Rabbit anti-Mouse Polyclonal (aa128-157) Antibody
Mouse, Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
Cancer
Fast Shipping
PAK7/PAK5 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
PAK7/PAK5 Rabbit anti-Human Polyclonal (aa168-198) Antibody
Human
ELISA, IHC, IP, WB
Unconjugated
200 µl/$734
PAK7/PAK5 Rabbit anti-Human Polyclonal (aa168-198) (Biotin) Antibody
Human
ELISA, IHC, IP, WB
Biotin Conjugated
200 µl/$952
PAK7/PAK5 Rabbit anti-Human Polyclonal (aa168-198) (FITC) Antibody
Human
ELISA, IHC, IP, WB
FITC Conjugated
200 µl/$952
PAK7/PAK5 Rabbit anti-Human Polyclonal (aa168-198) (APC) Antibody
Human
ELISA, IHC, IP, WB
APC Conjugated
200 µl/$952
PAK7/PAK5 Rabbit anti-Human Polyclonal (aa168-198) (Azide-free) (HRP) Antibody
Human
ELISA, IHC, IP, WB
HRP Conjugated, Azide-free
200 µl/$952
PAK7/PAK5 Rabbit anti-Human Polyclonal (aa168-198) (PE) Antibody
Human
ELISA, IHC, IP, WB
PE Conjugated
200 µl/$952
Fast Shipping
PAK7/PAK5 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, IHC, IHC-P
Unconjugated
50 µg/$460
Baculovirus
6His, N-terminus
100 µg/$1,164; 20 µg/$475; 1 mg/$2,187
PAK7/PAK5 Rabbit anti-Mouse Polyclonal (aa128-157) Antibody
Mouse, Human
ELISA, IHC, WB
Unconjugated
200 µl/$734
PAK7/PAK5 Rabbit anti-Human Polyclonal (aa128-157) (Biotin) Antibody
Mouse, Human
ELISA, IHC, WB
Biotin Conjugated
200 µl/$952
PAK7/PAK5 Rabbit anti-Human Polyclonal (aa128-157) (FITC) Antibody
Mouse, Human
ELISA, IHC, WB
FITC Conjugated
200 µl/$952
PAK7/PAK5 Rabbit anti-Human Polyclonal (aa128-157) (APC) Antibody
Mouse, Human
ELISA, IHC, WB
APC Conjugated
200 µl/$952
PAK7/PAK5 Rabbit anti-Human Polyclonal (aa128-157) (Azide-free) (HRP) Antibody
Mouse, Human
ELISA, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
PAK7/PAK5 Rabbit anti-Human Polyclonal (aa128-157) (PE) Antibody
Mouse, Human
ELISA, IHC, WB
PE Conjugated
200 µl/$952
PAK7/PAK5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µl/$334; 100 µl/$397
PAK7/PAK5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
100 µg/$357
PAK7/PAK5 Rabbit anti-Human Polyclonal (630-710 aa, C-terminal) Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
PAK7/PAK5 Rabbit anti-Human Polyclonal (aa168-198) Antibody
Human
IHC, IHC-P, WB
Unconjugated
400 µl/$393
PAK7/PAK5 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µg/$575
PAK7/PAK5 Rabbit anti-Human Polyclonal (aa26-55) Antibody
Rabbit, Mouse, Dog, Sheep, Rat, Hamster, Horse, Bat, Human
IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
PAK7/PAK5 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human, Monkey
IHC, IHC-P, WB
Unconjugated
100 µl/$299
PAK7/PAK5 Rabbit anti-Human Polyclonal (Glu693) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
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