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PDPN / Podoplanin
podoplanin
May be involved in cell migration and/or actin cytoskeleton organization. When expressed in keratinocytes, induces changes in cell morphology with transfected cells showing an elongated shape, numerous membrane protrusions, major reorganization of the actin cytoskeleton, increased motility and decreased cell adhesion. Required for normal lung cell proliferation and alveolus formation at birth. Induces platelet aggregation. Does not have any effect on folic acid or amino acid transport. Does not function as a water channel or as a regulator of aquaporin-type water channels.
| Gene Name: | podoplanin |
| Synonyms: | PDPN, AGGRUS, HT1alpha-1, Glycoprotein 36, Glycoprotein, 36-KD, gp36, gp38, OTS8, PA2.26, PA2.26 antigen, Podoplanin, T1A, gp40, HT1A-1, HT1alpha-2, p38, T1-alpha, T1A-2 |
| Target Sequences: | NM_006474 NP_006465.3 Q86YL7 |
Publications (14)
1
Characterization of an antigenic determinant preferentially expressed by type I epithelial cells in the murine thymus. Farr A, Nelson A, Hosier S. The journal of histochemistry and cytochemistry : official journal of the Histochemistry Society. 1992 40:651-64.
[PubMed:1374092]
2
Characterization and cloning of a novel glycoprotein expressed by stromal cells in T-dependent areas of peripheral lymphoid tissues. Farr AG, Berry ML, Kim A, Nelson AJ, Welch MP, Aruffo A. The Journal of experimental medicine. 1992 176:1477-82.
[PubMed:1402691]
[PMC:PMC2119410]
3
T1alpha/podoplanin deficiency disrupts normal lymphatic vasculature formation and causes lymphedema. Schacht V, Ramirez MI, Hong YK, Hirakawa S, Feng D, Harvey N, Williams M, Dvorak AM, Dvorak HF, Oliver G, Detmar M. The EMBO journal. 2003 22:3546-56.
[PubMed:12853470]
[PMC:PMC165612]
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PDPN / Podoplanin
(123)
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Human
(67)
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(32)
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(12)
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(1)
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(35)
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(11)
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(31)
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(64)
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(4)
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(28)
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(16)
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(5)
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(35)
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(49)
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(49)
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(8)
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(8)
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(7)
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(5)
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(4)
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(4)
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(1)
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(1)
aa1-206
(1)
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(1)
aa187-200
(1)
aa226-238
(1)
Publications
No
(122)
Yes
(1)
Sample Type
Cell Culture Supernatants
(1)
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(3)
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(10)
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(10)
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(5)
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6His, C-terminus
(2)
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(5)
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(1)
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(2)
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(2)
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(1)
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(4)
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(10)
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(5)
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(1)
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(2)
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(3)
HEK 293 Cells
(3)
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(4)
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(4)
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(1)
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(5)
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Low endotoxin level
(10)
PDPN / Podoplanin Rabbit anti-Human Polyclonal (aa23-143) Antibody
Pig, Human
ICC, IHC-Fr, IHC-P, WB
Unconjugated
100 µl/$460
PDPN / Podoplanin Syrian hamster anti-Mouse Monoclonal (8.1.1) Antibody
Mouse
Flo, ICC, IHC, IHC-P, IP, WB
Unconjugated
0.1 ml/$386
PDPN / Podoplanin Mouse anti-Human Monoclonal (aa1-206) (5E2) Antibody
Mouse, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
Cancer Pathology
Cancer
PDPN / Podoplanin Mouse anti-Human Monoclonal (D2-40) Antibody
Mouse, Rat, Human
IHC-Fr, IHC-P
Unconjugated
0.05 ml/$460
PDPN / Podoplanin Mouse anti-Human Monoclonal (D2-40) Antibody
Mouse, Rat, Human
IHC-Fr, IHC-P
Unconjugated
0.1 ml/$343
Cancer Pathology
Cancer
PDPN / Podoplanin Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
PDPN / Podoplanin Rat anti-Mouse Monoclonal (8F11) Antibody
Mouse
Flo, IHC, IP, WB
Unconjugated
100 µg/$451
PDPN / Podoplanin Rabbit anti-Human Polyclonal (aa97-146) Antibody
Human
IHC, IHC-P, WB
Unconjugated
100 µl/$424
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$730
Sandwich
96-Well Microplate
Mouse
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
PDPN / Podoplanin Hamster-Golden Syrian anti-Mouse Monoclonal (DY488) (8.1.1) Antibody
Mouse
Flo, ICC, IHC, IHC-P, IP, WB
DY488 Conjugated
0.1 ml/$416
PDPN / Podoplanin Mouse anti-Human Monoclonal (4D5aE5E6) Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
0.1 mg/$486
PDPN / Podoplanin Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC-P, WB
Unconjugated
50 µl/$460
PDPN / Podoplanin Hamster-Golden Syrian anti-Mouse Monoclonal (DY650) (8.1.1) Antibody
Mouse
Flo, ICC, IHC, IHC-P, IP, WB
DY650 Conjugated
0.1 ml/$416
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Tissue Homogenates
1 Plate/$783
PDPN / Podoplanin Rabbit anti-Rat Polyclonal (aa155-166) Antibody
Rat
WB
Unconjugated
10 µg/$318; 100 µg/$470
PDPN / Podoplanin Hamster-Golden Syrian anti-Mouse Monoclonal (Biotin) (8.1.1) Antibody
Mouse
Flo, ICC, IHC, IHC-P, IP, WB
Biotin Conjugated
0.1 ml/$416
Sandwich
96-Well Microplate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$586
E. coli
His-GST
42.2 kDa
10 µg/$275; 50 µg/$402; 100 µg/$642; 200 µg/$802; 1 mg/$1,876; 500 µg/$1,430; 5 mg/$2,838; 2 mg/$2,060
PDPN / Podoplanin Rabbit anti-Mouse Polyclonal (Preservative Free) Antibody
Mouse
ELISA, IHC-P, WB
Unconjugated, Preservative Free
100 µl/$412
PDPN / Podoplanin Rabbit anti-Human Polyclonal Antibody
Human
IF, IP, WB
Unconjugated
200 µg/$807
PDPN / Podoplanin Rabbit anti-Human Polyclonal Antibody
Human
IF, IP, WB
Unconjugated
100 µg/$415; 200 µg/$531
PDPN / Podoplanin Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-Fr, IHC-P
Unconjugated
100 µg/$757
PDPN / Podoplanin Rat anti-Mouse Monoclonal (pmab-1) Antibody
Mouse
Flo, WB
Unconjugated
100 µg/$386
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of 123
product results
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