PR / Progesterone Receptor

progesterone receptor

The progesterone receptor, a NR3 Steroid Receptor, is induced in granulosa cells of preovulatory follicles in response to surges in luteinizing hormone. It is essential for ovulation and egg implantation. A decrease in expression of endometrial progesterone receptor results in infertility in women. This receptor mediates the progesterone-induced transcription of proteases including ADAMTS1 and cathepsin L. In breast cancer, progesterone receptors are associated with hormone dependence and prolonged survival. At least two alternatively spliced isoforms have been identified in human: hPR-A (94 kD) is 164 aa shorter than hPR-B (114 kD). In most cell contexts, hPR-B functions as a transcriptional activator of progesterone-responsive genes, whereas hPR-A functions as a transcriptional inhibitor of all steroid hormone receptors. hPR-A and hPR-B have been shown to regulate different sets of genes in human breast cancer cells. Some of these PR-regulated genes are implicated in breast cancer.

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Products

Proteins (8)

Type

Over-Expression Lysate (2)

Recombinant (6)

Target

PR / Progesterone Receptor (8)

Publications

No (8)

Tag

GST, N-terminus (1)

His (1)

His, N-terminus (1)

His-SUMO (1)

His-T7 (1)

Myc-DDK (Flag) (3)

Species

Human (4)

Pig (2)

Rat (1)

Source

293T Cells (1)

E. coli (3)

HEK 293 Cells (2)

Wheat Germ Extract (1)

Yeast (1)

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Human PR / Progesterone Receptor Protein (Recombinant His, N-terminus) - LS-G133375

Source:

E. coli

Tag:

His, N-terminus

Molecular Weight:

20.4 kDa

Price:

10 µg/$275; 50 µg/$402; 200 µg/$805; 100 µg/$645; 1 mg/$1,881; 500 µg/$1,435; 5 mg/$2,844; 2 mg/$2,065

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Rat PR / Progesterone Receptor Protein (Recombinant His-T7) (aa672-790) - LS-G13608

Source:

E. coli

Tag:

His-T7

Molecular Weight:

17.5 kDa

Price:

10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231

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Human PR / Progesterone Receptor Protein (Recombinant GST, N-terminus) (aa1-110) - LS-G59586

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human PR / Progesterone Receptor Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G66662

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

98.8 kDa

Price:

20 µg/$1,107

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Human PR / Progesterone Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G78237

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

98.8 kDa

Price:

20 µg/$215

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PR / Progesterone Receptor Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G122927

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

98.8 kDa

Price:

100 µg/$710

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Pig PR / Progesterone Receptor Protein (Recombinant His) (aa31-229) - LS-G23085

Source:

Yeast

Tag:

His

Molecular Weight:

24.9 kD

Price:

100 µg/$679; 20 µg/$429; 1 mg/$1,973

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Pig PR / Progesterone Receptor Protein (Recombinant His-SUMO) (aa31-229) - LS-G21080

Source:

E. coli

Tag:

His-SUMO

Molecular Weight:

38.9 kD

Price:

1 mg/$1,679; 100 µg/$598; 20 µg/$405

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