Rho Kinase / ROCK1

Rho-associated, coiled-coil containing protein kinase 1

Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. Involved in regulation of smooth muscle contraction, actin cytoskeleton organization, stress fiber and focal adhesion formation, neurite retraction, cell adhesion and motility via phosphorylation of DAPK3, GFAP, LIMK1, LIMK2, MYL9/MLC2, PFN1 and PPP1R12A. Phosphorylates FHOD1 and acts synergistically with it to promote SRC-dependent non-apoptotic plasma membrane blebbing. Phosphorylates JIP3 and regulates the recruitment of JNK to JIP3 upon UVB-induced stress. Acts as a suppressor of inflammatory cell migration by regulating PTEN phosphorylation and stability. Acts as a negative regulator of VEGF-induced angiogenic endothelial cell activation. Required for centrosome positioning and centrosome-dependent exit from mitosis. Plays a role in terminal erythroid differentiation. May regulate closure of the eyelids and ventral body wall by inducing the assembly of actomyosin bundles. Promotes keratinocyte terminal differentiation. Involved in osteoblast compaction through the fibronectin fibrillogenesis cell-mediated matrix assembly process, essential for osteoblast mineralization.

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Products

Antibodies (35)

Type

Primary (35)

Target

Rho Kinase / ROCK1 (35)

Reactivity

Human (34)

Mouse (25)

Rat (16)

Bat (1)

Bovine (2)

Dog (1)

Horse (1)

Monkey (3)

Pig (1)

Rabbit (1)

Application

IHC (11)

IHC-P (4)

WB (31)

Flo (1)

ELISA (6)

ICC (5)

IF (5)

IP (6)

Peptide-ELISA (1)

Host

rabbit (31)

mouse (4)

Product Group

IHCPlus (1)

Isotype

IgG (19)

IgG1 (2)

IgG1,k (1)

Clonality

monoclonal mc (6)

polyclonal pc (29)

Clone

154C1465 (1)

1H4 (2)

2E2 (1)

Format

APC (1)

APC Conjugated (1)

Biotin Conjugated (1)

Cy3 Conjugated (1)

Cy7 Conjugated (1)

FITC Conjugated (1)

HRP Conjugated (1)

PE Conjugated (1)

Preservative Free (1)

Unconjugated (28)

Epitope

aa1094-1323 (8)

Internal (2)

Asn311 (1)

Ser282 (1)

Tyr913 (1)

aa107-371 (1)

aa1114-1126 (1)

aa1300-C-term (1)

aa262-311 (1)

aa400-450 (1)

Publications

No (35)

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IHC-plus™ Rho Kinase / ROCK1 Antibody LS-B7100

(4.0) Rating

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, ICC, IF, IHC, IHC-P, WB

Format:

Unconjugated

Price:

0.05 mg/$460

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Rho Kinase / ROCK1 Antibody LS-C497794

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Monoclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

Flo, IF, IHC, IP, WB

Format:

Unconjugated

Price:

20 µl/$299; 100 µl/$431

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Rho Kinase / ROCK1 Antibody (clone 2E2) LS-C198099

Antibody:

Rho Kinase / ROCK1 Mouse anti-Human Monoclonal (2E2) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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Rho Kinase / ROCK1 Antibody (clone 1H4) LS-C169453

Antibody:

Rho Kinase / ROCK1 Mouse anti-Human Monoclonal (1H4) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µl/$459

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Rho Kinase / ROCK1 Antibody LS-C75509

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Monoclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

20 µl/$453; 100 µl/$643

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Rho Kinase / ROCK1 Antibody (aa1114-1126, clone 154C1465) LS-C511

Antibody:

Rho Kinase / ROCK1 Mouse anti-Human Monoclonal (aa1114-1126) (154C1465) Antibody

Reactivity:

Mouse, Dog, Bovine, Rat, Horse, Bat, Human, Monkey

Applications:

WB

Format:

Unconjugated

Price:

0.1 mg/$386

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Rho Kinase / ROCK1 Antibody (aa107-371) LS-C186291

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal (aa107-371) Antibody

Reactivity:

Human

Applications:

ICC, IHC, IHC-P, WB

Format:

Unconjugated

Price:

100 µl/$450

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Rho Kinase / ROCK1 Antibody (Internal) LS-C385933

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

ELISA, ICC, IHC, WB

Format:

Unconjugated

Price:

50 µg/$295; 100 µg/$335; 200 µg/$394

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Rho Kinase / ROCK1 Antibody LS-C408278

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IP, WB

Format:

Unconjugated

Price:

20 µl/$287; 100 µl/$431

Select

Rho Kinase / ROCK1 Antibody (Internal) LS-C352778

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal (Internal) Antibody

Reactivity:

Rabbit, Mouse, Bovine, Rat, Pig, Human, Monkey

Applications:

ICC, IF, WB

Format:

Unconjugated

Price:

100 µl/$299

Select

Rho Kinase / ROCK1 Antibody LS-C660577

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

Rho Kinase / ROCK1 Antibody LS-C660578

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IHC, WB

Format:

Unconjugated

Price:

100 µg/$341

Select

Rho Kinase / ROCK1 Antibody LS-C820531

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ICC, IF

Format:

Unconjugated

Price:

100 µl/$412

Select

Rho Kinase / ROCK1 Antibody (Asn311) LS-C177597

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal (Asn311) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$321; 100 µl/$403

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Rho Kinase / ROCK1 Antibody (aa262-311) LS-C291734

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal (aa262-311) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, Peptide-ELISA, WB

Format:

Unconjugated

Price:

50 µl/$334; 100 µl/$397

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Rho Kinase / ROCK1 Antibody LS-C772827

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

60 µl/$343; 120 µl/$427; 200 µl/$559

Select

Rho Kinase / ROCK1 Antibody LS-C770312

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Mouse Polyclonal Antibody

Reactivity:

Mouse, Rat

Applications:

IHC

Format:

Unconjugated

Price:

60 µl/$307; 120 µl/$367; 200 µl/$457

Select

Rho Kinase / ROCK1 Antibody (aa1300-C-term) LS-C287341

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal (aa1300-C-term) Antibody

Reactivity:

Mouse, Human

Applications:

IP, WB

Format:

Unconjugated

Price:

10 µl/$295; 100 µl/$514

Select

Rho Kinase / ROCK1 Antibody LS-C746275

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$448

Select

Rho Kinase / ROCK1 Antibody (aa1094-1323) LS-C374823

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Mouse Polyclonal (aa1094-1323) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µl/$311; 200 µl/$355; 500 µl/$499; 1 ml/$571; 2 ml/$777; 5 ml/$1,261

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Rho Kinase / ROCK1 Antibody (clone 1H4) LS-C759699

Antibody:

Rho Kinase / ROCK1 Mouse anti-Human Monoclonal (1H4) Antibody

Reactivity:

Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$503

Select

Rho Kinase / ROCK1 Antibody (Ser282) LS-C778187

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal (Ser282) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$357

Select

Rho Kinase / ROCK1 Antibody LS-C777747

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$357

Select

Rho Kinase / ROCK1 Antibody LS-C777909

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$357

Select

Rho Kinase / ROCK1 Antibody (Tyr913) LS-C779220

Antibody:

Rho Kinase / ROCK1 Rabbit anti-Human Polyclonal (Tyr913) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

WB

Format:

Unconjugated

Price:

100 µg/$357

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