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SCN1A / Nav1.1

sodium channel, voltage-gated, type I, alpha subunit

The vertebrate sodium channel is a voltage-gated ion channel essential for the generation and propagation of action potentials, mainly in nerve and muscle. Voltage-sensitive sodium channels are heteromeric complexes consisting of a large central pore-forming glycosylated alpha subunit, and two smaller auxiliary beta subunits. This gene encodes the large alpha subunit, and mutations in this gene have been associated with several epilepsy, convulsion and migraine disorders. Alternative splicing results in multiple transcript variants. The RefSeq Project has decided to create four representative RefSeq records. Three of the transcript variants are supported by experimental evidence and the fourth contains alternate 5' untranslated exons, the exact combination of which have not been experimentally confirmed for the full-length transcript.

Gene Name: sodium channel, voltage-gated, type I, alpha subunit
Family/Subfamily: Ion Channel , Sodium channel - voltage-gated
Synonyms: SCN1A, Brain sodium channel type I, FEB3A, FHM3, GEFSP2, EIEE6, HBSC I, HBSCI, GEFS+2, NAC1, Nav1.1, SCN1, SMEI, FEB3, Febrile convulsions 3, RBI
Target Sequences: NM_006920 NP_008851.3 P35498

☰ Filters
Antibodies (16)
Primary (16)
SCN1A / Nav1.1 (16)
Human (16)
Mouse (11)
Rat (14)
Bat (1)
Bovine (1)
Chicken (1)
Dog (2)
Hamster (1)
Horse (2)
Monkey (1)
Pig (1)
Rabbit (2)
Sheep (1)
Xenopus (1)
IHC (7)
IHC-P (3)
WB (11)
Flo (1)
ELISA (7)
IF (1)
Peptide-ELISA (2)
rabbit (16)
Product Group
IHCPlus (2)
Ig (1)
IgG (7)
polyclonal pc (16)
Unconjugated (16)
Internal (2)
1440-1520 aa, Internal (1)
N-Terminus (1)
aa1981-2009 (1)
aa33-82 (1)
No (16)
SCN1A / Nav1.1 Antibody - Anti-SCN1A / Nav1.1 antibody IHC of human brain, cerebellum. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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SCN1A / Nav1.1 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Xenopus, Chicken, Rabbit, Mouse, Dog, Rat, Hamster, Pig, Horse, Bat, Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$440
SCN1A / Nav1.1 Antibody - Western blot of Na+ CP-pan antibody
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SCN1A / Nav1.1 Rabbit anti-Human Polyclonal (1440-1520 aa, Internal) Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
SCN1A / Nav1.1 Antibody - Anti-SCN1A Antibody (Center) at 1:2000 dilution + U-87 MG whole cell lysate Lysates/proteins at 20 µg per lane. Secondary Goat Anti-Rabbit IgG, (H+L), Peroxidase conjugated at 1/10000 dilution. Predicted band size: 229 kDa Blocking/Dilution buffer: 5% NFDM/TBST.
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SCN1A / Nav1.1 Rabbit anti-Human Polyclonal (Internal) Antibody
Human
ELISA, Flo, WB
Unconjugated
200 µl/$393
SCN1A / Nav1.1 Antibody - Immunohistochemical analysis of Nav1.1 staining in human brain formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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SCN1A / Nav1.1 Rabbit anti-Human Polyclonal (Internal) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
SCN1A / Nav1.1 Antibody - Western blot analysis of lysates from mouse brain tissue, using Na+ CP type Iα antibody.
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SCN1A / Nav1.1 Rabbit anti-Human Polyclonal (aa33-82) Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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SCN1A / Nav1.1 Rabbit anti-Human Polyclonal Antibody
Human
ELISA
Unconjugated
50 µl/$294; 100 µl/$360
SCN1A / Nav1.1 Antibody - Western blot analysis of Scn1a expression in rat brain extract (lane 1), mouse brain extract (lane 2) and U87 whole cell lysates (lane 4). Scn1a at 250 kD was detected using rabbit anti- Scn1a Antigen Affinity purified polyclonal antibody at 0.5 ug/mL. The blot was developed using chemiluminescence (ECL) method.
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SCN1A / Nav1.1 Rabbit anti-Human Polyclonal (aa1981-2009) Antibody
Rabbit, Mouse, Dog, Sheep, Bovine, Rat, Horse, Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
SCN1A / Nav1.1 Antibody - Anti-SCN1A / Nav1.1 antibody IHC of human pancreas, exocrine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 20 ug/ml.
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SCN1A / Nav1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$485
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SCN1A / Nav1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
SCN1A / Nav1.1 Antibody - Immunohistochemistry of paraffin-embedded Human esophagus cancer using SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/13A Polyclonal Antibody at dilution of 1:50.
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SCN1A / Nav1.1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
SCN1A / Nav1.1 Antibody - Western blot analysis Na+ CP type I alpha using HepG2 whole cells lysates
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SCN1A / Nav1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
SCN1A / Nav1.1 Antibody - Immunohistochemistry of paraffin-embedded Human lung cancer using SCN1A/2A/3A/4A/5A/8A/9A/10A/11A/12A Polyclonal Antibody at dilution of 1:40.
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SCN1A / Nav1.1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, IHC
Unconjugated
20 µl/$254; 60 µl/$296; 120 µl/$355; 200 µl/$450
Select
SCN1A / Nav1.1 Rabbit anti-Human Polyclonal Antibody
Rat, Human
ELISA, WB
Unconjugated
100 µg/$357
SCN1A / Nav1.1 Antibody - Western blot of SCN-pan antibody at 1:500 dilution. Lane 1: HEK293T whole cell lysate. Lane 2: RAW264.7 whole cell lysate.
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SCN1A / Nav1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
50 µl/$321; 100 µl/$403
SCN1A / Nav1.1 Antibody
Select
SCN1A / Nav1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
WB
Unconjugated
100 µg/$575
Select
SCN1A / Nav1.1 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Unconjugated
100 µl/$357
Viewing 1-16 of 16 product results



If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).