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SERPINF1 / PEDF

serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1

Neurotrophic protein; induces extensive neuronal differentiation in retinoblastoma cells. Potent inhibitor of angiogenesis. As it does not undergo the S (stressed) to R (relaxed) conformational transition characteristic of active serpins, it exhibits no serine protease inhibitory activity.

Gene Name: serpin peptidase inhibitor, clade F (alpha-2 antiplasmin, pigment epithelium derived factor), member 1
Synonyms: SERPINF1, EPC-1, OI12, PEDF, Serpin F1, PIG35, OI6
Target Sequences: NM_002615 NP_002606.3 P36955

Publications (4)

1
Differentiation of human pluripotent stem cells to retinal pigmented epithelium in defined conditions using purified extracellular matrix proteins. Rowland TJ, Blaschke AJ, Buchholz DE, Hikita ST, Johnson LV, Clegg DO. Journal of tissue engineering and regenerative medicine. 2013 August;7:642-653. [Full Text Article] [PubMed:22514096] Related Antibodies: LS-B2471.
2
Malignant ascites: a source of therapeutic protein against ovarian cancer?. Ribaux P, Britan A, Thumann G, Delie F, Petignat P, Cohen M. Oncotarget. 2019 October;10:5894-5905. [Full Text Article] [PubMed:31666922] [PMC:PMC6800269] Related Antibodies: LS-C100901.
3
CSF1R blockade induces macrophage ablation and results in mouse choroidal vascular atrophy and RPE disorganization. Xiao Yang, Lian Zhao, Maria M Campos, Mones Abu-Asab, Davide Ortolan, Nathan Hotaling, Kapil Bharti, Wai T Wong. eLife. 2020 Apr;9:e55564. [Full Text Article] [PubMed:32234210] [PMC:PMC7156269]
4
Preterm birth prediction in asymptomatic women at mid-gestation using a panel of novel protein biomarkers: the Prediction of PreTerm Labor (PPeTaL) study. San Min Leow, Megan K W Di Quinzio, Zhen Long Ng, Claire Grant, Tal Amitay, Ying Wei, Moshe Hod, Penelope M Sheehan, Shaun P Brennecke, Nir Arbel, Harry M Georgiou. The Breast : official journal of the European Society of Mastology. 2020 May;;2:100084. [Full Text Article] [PubMed:33345955]
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☰ Filters
Products
Proteins (26)
Over-Expression Cell Culture Supernatant (1)
Over-Expression Lysate (3)
Recombinant (22)
SERPINF1 / PEDF (26)
No (26)
6His, C-terminus (2)
6His, N-terminus (4)
DDK (Flag) (2)
GST (2)
His (2)
His, C-Terminal (1)
His, N-Terminal (1)
His,C-terminus (1)
His-S (1)
His-SUMO, N-terminus (1)
His-T7 (1)
Myc-DDK (Flag) (3)
Human (11)
Mouse (11)
Pig (1)
Rat (2)
293T Cells (1)
CHO Cells (2)
E. coli (13)
HEK 293 Cells (7)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (6)
Low endotoxin level (11)
Biologically active (1)
Select
HEK 293 Cells
6His, N-terminus
46 kDa
200 µl/$283
Select
HEK 293 Cells
His, C-Terminal
Less than 1.0 EU/µg protein (determined by LAL method).
45.8 kDa
50 µg/$556
Select
CHO Cells
DDK (Flag)
Less than 0.01 EU/µg protein (determined by LAL method).
~47kDa (SDS-PAGE)
10 µg/$372
Select
E. coli
GST
71.9 kD
1 mg/$1,679; 100 µg/$500; 20 µg/$364
Select
E. coli
None
Biologically active
Less than 1 EU/µg (determined by LAL method).
44.4 kDa
1 mg/$3,412; 20 µg/$364
SERPINF1 / PEDF Protein - SDS-PAGE under reducing conditions and visualized by Coomassie blue staining
Select
E. coli
6His, N-terminus
46 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Select
E. coli
None
Less than 0.1 ng/µg of protein (less than 1EU/µg).
44.5 kDa
5 µg/$268; 20 µg/$349
Select
CHO Cells
DDK (Flag)
Less than 0.1 EU/µg protein (determined by LAL method).
~47kDa (SDS-PAGE)
10 µg/$365
SERPINF1 / PEDF Protein - Recombinant  Pigment Epithelium Derived Factor By SDS-PAGE
Select
E. coli
His-T7
47.8 kDa
10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176
SERPINF1 / PEDF Protein
Select
HEK 293 Cells
His, N-Terminal
~46 kDa
10 µg/$289; 100 µg/$432; 50 µg/$360
SERPINF1 / PEDF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
46.1 kDa
100 µg/$494
SERPINF1 / PEDF Protein
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
~45 kDa
10 µg/$291; 500 µg/$1,715; 1 mg/$2,707
Select
HEK 293 Cells
6His, N-terminus
46 kDa
100 µg/$298
SERPINF1 / PEDF Protein - 12.5% SDS-PAGE of human SERPINF1 stained with Coomassie Blue
Select
Wheat Germ Extract
GST
69.85 kDa
10 µg/$479; 25 µg/$670
SERPINF1 / PEDF Protein
Select
E. coli
6His, N-terminus
44 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
45.42kD
10 µg/$288; 50 µg/$442; 500 µg/$1,585; 1 mg/$2,157
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
42kD
10 µg/$281; 50 µg/$420; 500 µg/$1,585; 1 mg/$2,157
SERPINF1 / PEDF Protein - Purified recombinant protein SERPINF1 was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
46.1 kDa
20 µg/$1,107
SERPINF1 / PEDF Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
46.1 kDa
20 µg/$150
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
45.4 kDa
10 µg/$288; 50 µg/$436
Select
E. coli
None
Less than 1.0 EU/µg protein (determined by LAL method).
42.0 kDa
10 µg/$368; 50 µg/$504
Select
E. coli
His
19.0 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
SERPINF1 / PEDF Protein - Recombinant Pigment Epithelium Derived Factor By SDS-PAGE
Select
E. coli
His-S
47.0 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
SERPINF1 / PEDF Protein - Recombinant Pigment Epithelium Derived Factor By SDS-PAGE
Select
E. coli
His
17.1 kDa
10 µg/$287; 50 µg/$482; 100 µg/$770; 200 µg/$962; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
SERPINF1 / PEDF Protein - Recombinant Pigment Epithelium Derived Factor (PEDF) by SDS-PAGE
Select
E. coli
His-SUMO, N-terminus
58.2kDa
10 µg/$287; 50 µg/$482; 200 µg/$962; 100 µg/$770; 1 mg/$2,094; 500 µg/$1,623; 5 mg/$3,361; 2 mg/$2,284
Viewing 1-25 of 26 product results


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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).