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SHBG
sex hormone-binding globulin
Functions as an androgen transport protein, but may also be involved in receptor mediated processes. Each dimer binds one molecule of steroid. Specific for 5-alpha-dihydrotestosterone, testosterone, and 17-beta-estradiol. Regulates the plasma metabolic clearance rate of steroid hormones by controlling their plasma concentration.
| Gene Name: | sex hormone-binding globulin |
| Synonyms: | SHBG, ABP, SBP, Sex hormone-binding globulin, Sex steroid-binding protein, TEBG |
| Target Sequences: | NM_001040 NP_001031.2 P04278 |
Publications (1)
1
Modulation of SHBG binding to testosterone and estradiol by sex and morbid obesity. María Del Mar Grasa, José Gulfo, Núria Camps, Rosa Alcalá, Laura Monserrat, José María Moreno-Navarrete, Francisco José Ortega, Montserrat Esteve, Xavier Remesar, José Antonio Fernández-López, José Manuel Fernández-Real, Marià Alemany. European journal of endocrinology / European Federation of Endocrine Societies. 2017 April;176:393-404. [Full Text Article]
[PubMed:28077498]
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Proteins
(19)
Type
Native
(1)
Over-Expression Lysate
(8)
Recombinant
(10)
Target
SHBG
(19)
Publications
No
(19)
Tag
GST, N-terminus
(1)
His, N-Terminal
(2)
His-S
(3)
His-T7
(3)
Myc-DDK (Flag)
(9)
Species
Human
(11)
Mouse
(2)
Rat
(2)
Source
293F Cells
(2)
293T Cells
(4)
E. coli
(6)
HEK 293 Cells
(5)
Wheat Germ Extract
(1)
Purification
Purified
(3)
Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
38.4 kDa
20 µg/$1,107
E. coli
His-T7
22.5 kDa
10 µg/$268; 50 µg/$362; 100 µg/$577; 200 µg/$722; 1 mg/$1,755; 500 µg/$1,325; 5 mg/$2,708; 2 mg/$1,934
E. coli
His-T7
21.9 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
E. coli
His-T7
23.7 kDa
10 µg/$270; 50 µg/$372; 100 µg/$592; 200 µg/$742; 1 mg/$1,786; 500 µg/$1,352; 5 mg/$2,742; 2 mg/$1,966
293F Cells
His, N-Terminal
19kDa
10 µg/$315; 50 µg/$652; 200 µg/$1,228; 100 µg/$1,034; 1 mg/$2,469; 500 µg/$1,971; 5 mg/$4,551; 2 mg/$2,661
293F Cells
His, N-Terminal
20kDa
10 µg/$315; 50 µg/$652; 200 µg/$1,228; 100 µg/$1,034; 1 mg/$2,471; 500 µg/$1,972; 5 mg/$4,557; 2 mg/$2,663
293T Cells
Myc-DDK (Flag)
41.71 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
43.8 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
31.72 kDa
20 µg/$150
293T Cells
Myc-DDK (Flag)
32.36 kDa
20 µg/$150
HEK 293 Cells
Myc-DDK (Flag)
43.8 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
32.36 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
41.71 kDa
100 µg/$494
HEK 293 Cells
Myc-DDK (Flag)
31.72 kDa
100 µg/$494
E. coli
His-S
23.1 kDa
10 µg/$262; 50 µg/$339; 100 µg/$512; 200 µg/$642; 1 mg/$1,623; 500 µg/$1,214; 5 mg/$2,562; 2 mg/$1,796
E. coli
His-S
20.6 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
E. coli
His-S
20.3 kDa
10 µg/$259; 50 µg/$331; 100 µg/$482; 200 µg/$602; 1 mg/$1,553; 500 µg/$1,156; 5 mg/$2,481; 2 mg/$1,723
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