SMAD1

SMAD family member 1

SMAD1 belongs to the SMAD, a family of proteins similar to the gene products of the Drosophila gene 'mothers against decapentaplegic' (Mad) and the C. elegans gene Sma. SMAD proteins are signal transducers and transcriptional modulators that mediate multiple signaling pathways. This protein mediates the signals of the bone morphogenetic proteins (BMPs), which are involved in a range of biological activities including cell growth, apoptosis, morphogenesis, development and immune responses. In response to BMP ligands, this protein can be phosphorylated and activated by the BMP receptor kinase. The phosphorylated form of this protein forms a complex with SMAD4, which is important for its function in the transcription regulation. This protein is a target for SMAD-specific E3 ubiquitin ligases, such as SMURF1 and SMURF2, and undergoes ubiquitination and proteasome-mediated degradation. Alternatively spliced transcript variants encoding the same protein have been observed.

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Products

ELISA Kits (26)

Type

Cell-Based (1)

Cell-Based Phosphorylation (2)

Custom (3)

Development Kit (1)

DNA Binding (1)

DNA Binding Phosphorylation (2)

Sandwich (15)

Sandwich CLIA (1)

Target

SMAD1 (26)

Reactivity

Human (12)

Mouse (10)

Rat (9)

Chicken (1)

Monkey (1)

Porcine (1)

Rabbit (1)

Sheep (1)

Product Group

DevKit DuoPlus (1)

Format

12 x 8-Well Microstrips (4)

96-Well Microplate (6)

96-Well Strip Plate (15)

Antibody Pair and Standard (1)

Publications

No (26)

Sample Type

Adherent Cell Cultures (3)

Cell Culture Supernatants (3)

Cell Lysates (6)

Nuclear Lysates (3)

Plasma (10)

Serum (10)

Tissue Homogenates (5)

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Mouse/Human/Rat Phospho-SMAD1 (Ser465) (DNA-Binding Phosphorylation ELISA) ELISA Kit - LS-F925

Type:

DNA Binding Phosphorylation

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$735

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Bovine SMAD1 (Custom ELISA) ELISA Kit - LS-F14959

Type:

Custom

Format:

96-Well Strip Plate

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Rat SMAD1 (Custom ELISA) ELISA Kit - LS-F14960

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Rat

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Mouse SMAD1 (Custom ELISA) ELISA Kit - LS-F14961

Type:

Custom

Format:

96-Well Strip Plate

Reactivity:

Mouse

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$669

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Human SMAD1 (Sandwich ELISA) ELISA Kit - LS-F12613

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1.56 - 100 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$669

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Human SMAD1 (Sandwich ELISA) ELISA Kit - LS-F25218

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

1 Plate/$782

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Human SMAD1 (Sandwich ELISA) ELISA Kit - LS-F22735

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Human

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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Rabbit SMAD1 (Sandwich ELISA) ELISA Kit - LS-F22426

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rabbit

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

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Rat SMAD1 (Sandwich ELISA) ELISA Kit - LS-F22331

Type:

Sandwich

Format:

96-Well Microplate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

Select

Human SMAD1 (Sandwich ELISA) ELISA Kit - LS-F27251

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Rat SMAD1 (Sandwich ELISA) ELISA Kit - LS-F27596

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

1 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$805

Select

Mouse/Human Phospho-SMAD1 (Ser187) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1372

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

2 Plates/$668

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Mouse/Human/Rat SMAD1 (Cell-Based ELISA) ELISA Kit - LS-F2311

Type:

Cell-Based

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

1 Plate/$534

Select

Mouse/Human/Rat SMAD1 (DNA-Binding ELISA) ELISA Kit - LS-F843

Type:

DNA Binding

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$662

Select

Mouse/Human/Rat Phospho-SMAD1 (Ser187) (DNA-Binding Phosphorylation ELISA) ELISA Kit - LS-F907

Type:

DNA Binding Phosphorylation

Format:

12 x 8-Well Microstrips

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Lysates, Nuclear Lysates

Price:

1 Plate/$735

Select

Mouse/Human/Rat Phospho-SMAD1 (Ser465) (Cell-Based Phosphorylation ELISA) ELISA Kit - LS-F1056

Type:

Cell-Based Phosphorylation

Format:

96-Well Microplate

Reactivity:

Mouse, Human, Rat

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Adherent Cell Cultures

Price:

2 Plates/$668

Select

DevKit DuoPlus Mouse SMAD1 ELISA Development Kit - LS-F72089

Type:

Development Kit

Format:

Antibody Pair and Standard

Reactivity:

Mouse

Range:

0.625 - 40 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Cell Culture Supernatants, Cell Lysates, Tissue Homogenates

Price:

500 Wells/$1,302; 1000 Wells/$1,947

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Rat SMAD1 (Sandwich ELISA) ELISA Kit - LS-F33662

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Rat

Range:

0.313 - 20 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Chicken SMAD1 (Sandwich ELISA) ELISA Kit - LS-F45790

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Chicken

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Monkey SMAD1 (Sandwich ELISA) ELISA Kit - LS-F45791

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Monkey

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Porcine SMAD1 (Sandwich ELISA) ELISA Kit - LS-F45792

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Porcine

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$656

Select

Sheep SMAD1 (Sandwich ELISA) ELISA Kit - LS-F45793

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Sheep

Range:

0.391 - 25 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Price:

1 Plate/$691

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Human SMAD1 (CLIA) ELISA Kit - LS-F29641

Type:

Sandwich CLIA

Format:

12 x 8-Well Microstrips

Reactivity:

Human

Range:

0.156 - 10 ng/ml

Detection:

Chemiluminescent

Sample Types:

Plasma, Serum

Price:

1 Plate/$656

Select

Human SMAD1 (Sandwich ELISA) ELISA Kit - LS-F37230

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Human

Range:

0.781 - 50 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum, Tissue Homogenates

Price:

1 Plate/$579

Select

Mouse SMAD1 (Sandwich ELISA) ELISA Kit - LS-F38424

Type:

Sandwich

Format:

96-Well Strip Plate

Reactivity:

Mouse

Range:

0.156 - 10 ng/ml

Detection:

Colorimetric - 450nm (TMB)

Sample Types:

Plasma, Serum

Price:

1 Plate/$586

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