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TBX2

T-box 2

TBX2 is a member of a phylogenetically conserved family of genes that share a common DNA-binding domain, the T-box. T-box genes encode transcription factors involved in the regulation of developmental processes. This gene product is the human homolog of mouse Tbx2, and shares strong sequence similarity with Drosophila omb protein. Expression studies indicate that this gene may have a potential role in tumorigenesis as an immortalizing agent. Transcript heterogeneity due to alternative polyadenylation has been noted for this gene.

Gene Name: T-box 2
Synonyms: TBX2, T-box 2, T-box protein 2
Target Sequences: NM_005994 NP_005985.3 Q13207

Publications (2)

1
TBX2 expression is associated with platinum-sensitivity of ovarian serous carcinoma. Tasaka R, Fukuda T, Shimomura M, Inoue Y, Wada T, Kawanishi M, Yasui T, Sumi T. Oncology letters. 2018 March;15:3085-3090. (Human) [Full Text Article] [PubMed:29435041] [PMC:PMC5778828] Related Antibodies: LS-C402301.
2
T-box 2 expression is a useful indicator of the response to neoadjuvant chemotherapy for patients with locally advanced uterine cervical squamous cell carcinoma. Yuta Inoue, Takeshi Fukuda, Shigenori Nanno, Yuichiro Awazu, Masahiro Shimomura, Hiroaki Matsubara, Makoto Yamauchi, Tomoyo Yasui, Toshiyuki Sumi. Oncology letters. 2021 Nov;;22:755. [Full Text Article] [PubMed:34539859] [PMC:PMC8436333] Related Antibodies: LS-C402301.

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ELISA Kits (5)
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TBX2 (5)
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TBX2 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum, Tissue Homogenates
1 Plate/$579
TBX2 ELISA Kit
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Cell-Based
96-Well Microplate
Mouse, Human
Colorimetric - 450nm (TMB)
Adherent Cell Cultures
1 Plate/$618
TBX2 ELISA Kit
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Sandwich
96-Well Strip Plate
Human
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
TBX2 ELISA Kit
Select
Sandwich
96-Well Strip Plate
Rat
0.156 - 10 ng/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$651
TBX2 ELISA Kit
Select
DNA Binding
12 x 8-Well Microstrips
Mouse, Human
Colorimetric - 450nm (TMB)
Cell Lysates, Nuclear Lysates
1 Plate/$694
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If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.

PLEASE NOTE

For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).