TCF7L2 / TCG4

transcription factor 7-like 2 (T-cell specific, HMG-box)

Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.

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Products

Antibodies (40)

Proteins (17)

ELISA Kits (4)

Type

Custom (1)

Over-Expression Lysate (14)

Primary (40)

Recombinant (3)

Sandwich (3)

Target

TCF7L2 / TCG4 (61)

Reactivity

Human (41)

Mouse (18)

Rat (17)

Bovine (9)

Chimpanzee (6)

Horse (3)

Monkey (1)

Pig (9)

Rabbit (3)

Zebrafish (3)

Application

IHC (11)

IHC-P (1)

WB (40)

ELISA (11)

ICC (1)

IF (1)

IP (3)

Peptide-ELISA (1)

Host

rabbit (37)

mouse (3)

Product Group

IHCPlus (1)

Isotype

IgG (18)

IgG,k (1)

IgG1,k (1)

IgG2a (1)

Clonality

monoclonal mc (4)

polyclonal pc (36)

Clone

1A9 (1)

3A4 (1)

Format

96-Well Strip Plate (4)

APC Conjugated (2)

Atto 390 Conjugated (1)

Atto 488 Conjugated (1)

Atto 594 Conjugated (1)

Biotin Conjugated (6)

DY488 Conjugated (1)

DY550 Conjugated (1)

DY650 Conjugated (1)

FITC Conjugated (5)

HRP Conjugated (4)

PE Conjugated (1)

PerCP Conjugated (1)

RPE Conjugated (1)

Unconjugated (14)

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Epitope

N-Terminus (9)

aa61-90 (7)

Internal (5)

aa251-300 (4)

Glu81 (1)

aa31-331 (1)

Publications

No (61)

Sample Type

Cell Lysates (1)

Plasma (2)

Serum (2)

Tissue Homogenates (2)

Tag

6His, N-terminus (1)

GST (1)

GST, N-terminus (1)

Myc-DDK (Flag) (14)

Species

Human (10)

Source

293T Cells (7)

E. coli (1)

HEK 293 Cells (7)

Wheat Germ Extract (2)

Purification

Purified (2)

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IHC-plus™ TCF7L2 / TCG4 Antibody (N-Terminus) LS-B7129

(4.0) Rating

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody

Reactivity:

Mouse, Rat, Human

Applications:

ELISA, IHC, IHC-P, WB

Format:

Unconjugated

Price:

50 µl/$460

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TCF7L2 / TCG4 Antibody (aa31-331) LS-C18042

Antibody:

TCF7L2 / TCG4 Mouse anti-Human Monoclonal (aa31-331) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, ICC, IHC, IP, WB

Format:

Unconjugated

Price:

200 µg/$882

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Human TCF7L2 / TCG4 Protein (Recombinant 6His, N-terminus) (aa1-456) - LS-G56990

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,679; 100 µg/$500; 20 µg/$364

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TCF7L2 / TCG4 Antibody (Glu81) LS-C39563

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Monoclonal (Glu81) Antibody

Reactivity:

Human

Applications:

IP, WB

Format:

Unconjugated

Price:

100 µl/$688

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TCF7L2 / TCG4 Antibody (aa61-90) LS-C161773

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (aa61-90) Antibody

Reactivity:

Mouse, Human

Applications:

WB

Format:

Unconjugated

Price:

400 µl/$393

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TCF7L2 / TCG4 Antibody (clone 3A4) LS-C105038

Antibody:

TCF7L2 / TCG4 Mouse anti-Human Monoclonal (3A4) Antibody

Reactivity:

Human

Applications:

ELISA, IF, WB

Format:

Unconjugated

Price:

100 µg/$423

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Human TCF7L2 / TCG4 Protein (Recombinant GST, N-terminus) (aa490-596) - LS-G60301

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Human TCF7L2 / TCG4 Protein (Recombinant GST) (Full Length) - LS-G30648

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

75.79 kDa

Price:

2 µg/$439

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TCF7L2 / TCG4 Antibody LS-C660938

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Human

Applications:

ELISA, IP, WB

Format:

Unconjugated

Price:

100 µg/$341

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TCF7L2 / TCG4 Antibody (clone 1A9) LS-C105037

Antibody:

TCF7L2 / TCG4 Mouse anti-Human Monoclonal (1A9) Antibody

Reactivity:

Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

100 µg/$423

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TCF7L2 / TCG4 Antibody LS-C775046

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Unconjugated

Price:

100 µg/$442

Select

TCF7L2 / TCG4 Antibody (aa61-90) LS-C330218

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (aa61-90) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

Unconjugated

Price:

200 µl/$734

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TCF7L2 / TCG4 Antibody (aa61-90, HRP) LS-C540627

Antibody:

TCF7L2 / TCG4 Rabbit anti-Mouse Polyclonal (aa61-90) (HRP) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

HRP Conjugated

Price:

200 µl/$952

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TCF7L2 / TCG4 Antibody (aa61-90, Biotin) LS-C520486

Antibody:

TCF7L2 / TCG4 Rabbit anti-Mouse Polyclonal (aa61-90) (Biotin) Antibody

Reactivity:

Mouse

Applications:

ELISA, WB

Format:

Biotin Conjugated

Price:

200 µl/$952

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TCF7L2 / TCG4 Antibody (aa61-90, FITC) LS-C241651

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (aa61-90) (FITC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

FITC Conjugated

Price:

200 µl/$952

Select

TCF7L2 / TCG4 Antibody (aa61-90, APC) LS-C241653

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (aa61-90) (APC) Antibody

Reactivity:

Mouse, Human

Applications:

ELISA, WB

Format:

APC Conjugated

Price:

200 µl/$952

• Unconjugated
• HRP
• Biotin
• FITC
• APC

• Unconjugated
• HRP
• Biotin
• More...
  • FITC
  • APC

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TCF7L2 / TCG4 Antibody (Biotin) LS-C777264

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (Biotin) Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Biotin Conjugated

Price:

100 µg/$475

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TCF7L2 / TCG4 Antibody (FITC) LS-C776653

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (FITC) Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

FITC Conjugated

Price:

100 µg/$472

Select

TCF7L2 / TCG4 Antibody (Atto 390) LS-C777351

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (Atto 390) Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Atto 390 Conjugated

Price:

100 µg/$479

Select

TCF7L2 / TCG4 Antibody (APC) LS-C777266

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (APC) Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

APC Conjugated

Price:

100 µg/$478

Select

TCF7L2 / TCG4 Antibody (RPE) LS-C775050

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (RPE) Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

RPE Conjugated

Price:

100 µg/$477

Select

TCF7L2 / TCG4 Antibody (PerCP) LS-C775048

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (PerCP) Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

PerCP Conjugated

Price:

100 µg/$478

Select

TCF7L2 / TCG4 Antibody (Atto 594) LS-C775053

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (Atto 594) Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Atto 594 Conjugated

Price:

100 µg/$479

Select

TCF7L2 / TCG4 Antibody (Atto 488) LS-C775051

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (Atto 488) Antibody

Reactivity:

Rat, Human

Applications:

IHC, WB

Format:

Atto 488 Conjugated

Price:

100 µg/$479

• Biotin
• FITC
• Atto 390
• APC
• RPE
• PerCP
• Atto 594
• More...
  • Atto 488

• Biotin
• FITC
• Atto 390
• More...
  • APC
  • RPE
  • PerCP
  • Atto 594
  • Atto 488

Select

TCF7L2 / TCG4 Antibody LS-C809716

Antibody:

TCF7L2 / TCG4 Rabbit anti-Human Polyclonal Antibody

Reactivity:

Mouse, Rat, Human, Monkey

Applications:

Peptide-ELISA, WB

Format:

Unconjugated

Price:

100 µl/$379; 200 µl/$421

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