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TCF7L2 / TCG4

transcription factor 7-like 2 (T-cell specific, HMG-box)

Participates in the Wnt signaling pathway and modulates MYC expression by binding to its promoter in a sequence-specific manner. Acts as repressor in the absence of CTNNB1, and as activator in its presence. Activates transcription from promoters with several copies of the Tcf motif 5'-CCTTTGATC-3' in the presence of CTNNB1. TLE1, TLE2, TLE3 and TLE4 repress transactivation mediated by TCF7L2/TCF4 and CTNNB1. Expression of dominant-negative mutants results in cell-cycle arrest in G1. Necessary for the maintenance of the epithelial stem-cell compartment of the small intestine.

Gene Name: transcription factor 7-like 2 (T-cell specific, HMG-box)
Family/Subfamily: Transcription factor , not assigned-Transcription factor
Synonyms: TCF7L2, HMG box transcription factor 4, HTCF-4, T-cell factor-4 variant X2, T-cell factor 4, Transcription factor 7-like 2, TCF-4
Target Sequences: NM_030756 NP_110383.2 Q9NQB0

☰ Filters
Antibodies (40)
Proteins (17)
ELISA Kits (4)
Custom (1)
Over-Expression Lysate (14)
Primary (40)
Recombinant (3)
Sandwich (3)
TCF7L2 / TCG4 (61)
Human (41)
Mouse (18)
Rat (17)
Bovine (9)
Chimpanzee (6)
Horse (3)
Monkey (1)
Pig (9)
Rabbit (3)
Zebrafish (3)
IHC (11)
IHC-P (1)
WB (40)
ELISA (11)
ICC (1)
IF (1)
IP (3)
Peptide-ELISA (1)
rabbit (37)
mouse (3)
Product Group
IHCPlus (1)
IgG (18)
IgG,k (1)
IgG1,k (1)
IgG2a (1)
monoclonal mc (4)
polyclonal pc (36)
1A9 (1)
3A4 (1)
96-Well Strip Plate (4)
APC Conjugated (2)
Atto 390 Conjugated (1)
Atto 488 Conjugated (1)
Atto 594 Conjugated (1)
Biotin Conjugated (6)
DY488 Conjugated (1)
DY550 Conjugated (1)
DY650 Conjugated (1)
FITC Conjugated (5)
HRP Conjugated (4)
PE Conjugated (1)
PerCP Conjugated (1)
RPE Conjugated (1)
Unconjugated (14)
N-Terminus (9)
aa61-90 (7)
Internal (5)
aa251-300 (4)
Glu81 (1)
aa31-331 (1)
No (61)
Cell Lysates (1)
Plasma (2)
Serum (2)
Tissue Homogenates (2)
6His, N-terminus (1)
GST (1)
GST, N-terminus (1)
Myc-DDK (Flag) (14)
Human (10)
293T Cells (7)
E. coli (1)
HEK 293 Cells (7)
Wheat Germ Extract (2)
Purified (2)
TCF7L2 / TCG4 Antibody - Anti-TCF7L2 antibody IHC of human kidney. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
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TCF7L2 / TCG4 Mouse anti-Human Monoclonal (aa31-331) Antibody
Mouse, Human
ELISA, ICC, IHC, IP, WB
Unconjugated
200 µg/$882
TCF7L2 / TCG4 Protein - (Tris-Glycine gel) Discontinuous SDS-PAGE (reduced) with 5% enrichment gel and 15% separation gel.
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E. coli
6His, N-terminus
1 mg/$1,679; 100 µg/$500; 20 µg/$364
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TCF7L2 / TCG4 Rabbit anti-Human Monoclonal (Glu81) Antibody
Human
IP, WB
Unconjugated
100 µl/$688
TCF7L2 / TCG4 Antibody - TCF7L2 Antibody western blot of mouse cerebellum tissue lysates (35 ug/lane). The TCF7L2 antibody detected the TCF7L2 protein (arrow).
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TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (aa61-90) Antibody
Mouse, Human
WB
Unconjugated
400 µl/$393
TCF7L2 / TCG4 Antibody - Immunofluorescence of monoclonal antibody to TCF7L2 on HeLa cell (antibody concentration 10 ug/ml).
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TCF7L2 / TCG4 Mouse anti-Human Monoclonal (3A4) Antibody
Human
ELISA, IF, WB
Unconjugated
100 µg/$423
TCF7L2 / TCG4 Protein - 12.5% SDS-PAGE of human TCF7L2 stained with Coomassie Blue
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Wheat Germ Extract
GST
75.79 kDa
2 µg/$439
TCF7L2 / TCG4 Protein - 12.5% SDS-PAGE Stained with Coomassie Blue.
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Wheat Germ Extract
GST, N-terminus
10 µg/$479; 25 µg/$670
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TCF7L2 / TCG4 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$341
TCF7L2 / TCG4 Antibody - TCF7L2 monoclonal antibody (M04), clone 1A9 Western blot of TCF7L2 expression in HeLa NE.
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TCF7L2 / TCG4 Mouse anti-Human Monoclonal (1A9) Antibody
Human
ELISA, WB
Unconjugated
100 µg/$423
TCF7L2 / TCG4 Antibody - Immunohistochemistry analysis using Rabbit Anti-TCF7L2 Polyclonal Antibody. Tissue: Colon Cancer. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-TCF7L2 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
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TCF7L2 / TCG4 Rabbit anti-Human Polyclonal Antibody
Rat, Human
IHC, WB
Unconjugated
100 µg/$442
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TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (aa61-90) Antibody
Mouse, Human
ELISA, WB
Unconjugated
200 µl/$734
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TCF7L2 / TCG4 Rabbit anti-Mouse Polyclonal (aa61-90) (HRP) Antibody
Mouse
ELISA, WB
HRP Conjugated
200 µl/$952
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TCF7L2 / TCG4 Rabbit anti-Mouse Polyclonal (aa61-90) (Biotin) Antibody
Mouse
ELISA, WB
Biotin Conjugated
200 µl/$952
Select
TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (aa61-90) (FITC) Antibody
Mouse, Human
ELISA, WB
FITC Conjugated
200 µl/$952
Select
TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (aa61-90) (APC) Antibody
Mouse, Human
ELISA, WB
APC Conjugated
200 µl/$952
TCF7L2 / TCG4 Antibody - Immunohistochemistry analysis using Rabbit Anti-TCF7L2 Polyclonal Antibody. Tissue: Colon Cancer. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-TCF7L2 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
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TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (Biotin) Antibody
Rat, Human
IHC, WB
Biotin Conjugated
100 µg/$475
TCF7L2 / TCG4 Antibody - Immunohistochemistry analysis using Rabbit Anti-TCF7L2 Polyclonal Antibody. Tissue: Colon Cancer. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-TCF7L2 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
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TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (FITC) Antibody
Rat, Human
IHC, WB
FITC Conjugated
100 µg/$472
TCF7L2 / TCG4 Antibody - Immunohistochemistry analysis using Rabbit Anti-TCF7L2 Polyclonal Antibody. Tissue: Colon Cancer. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-TCF7L2 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
Select
TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (Atto 390) Antibody
Rat, Human
IHC, WB
Atto 390 Conjugated
100 µg/$479
TCF7L2 / TCG4 Antibody - Immunohistochemistry analysis using Rabbit Anti-TCF7L2 Polyclonal Antibody. Tissue: Colon Cancer. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-TCF7L2 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
Select
TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (PerCP) Antibody
Rat, Human
IHC, WB
PerCP Conjugated
100 µg/$478
TCF7L2 / TCG4 Antibody - Immunohistochemistry analysis using Rabbit Anti-TCF7L2 Polyclonal Antibody. Tissue: Colon Cancer. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-TCF7L2 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
Select
TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (RPE) Antibody
Rat, Human
IHC, WB
RPE Conjugated
100 µg/$477
TCF7L2 / TCG4 Antibody - Immunohistochemistry analysis using Rabbit Anti-TCF7L2 Polyclonal Antibody. Tissue: Colon Cancer. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-TCF7L2 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
Select
TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (Atto 488) Antibody
Rat, Human
IHC, WB
Atto 488 Conjugated
100 µg/$479
TCF7L2 / TCG4 Antibody - Immunohistochemistry analysis using Rabbit Anti-TCF7L2 Polyclonal Antibody. Tissue: Colon Cancer. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-TCF7L2 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
Select
TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (Atto 594) Antibody
Rat, Human
IHC, WB
Atto 594 Conjugated
100 µg/$479
TCF7L2 / TCG4 Antibody - Immunohistochemistry analysis using Rabbit Anti-TCF7L2 Polyclonal Antibody. Tissue: Colon Cancer. Species: Human. Fixation: Formalin Fixed Paraffin-Embedded. Primary Antibody: Rabbit Anti-TCF7L2 Polyclonal Antibody  at 1:50 for 30 min at RT. Counterstain: Hematoxylin. Magnification: 10X. HRP-DAB Detection.
Select
TCF7L2 / TCG4 Rabbit anti-Human Polyclonal (APC) Antibody
Rat, Human
IHC, WB
APC Conjugated
100 µg/$478
TCF7L2 / TCG4 Antibody - Western blot analysis of TCF7L2 using COLO205 whole lysates.
Select
TCF7L2 / TCG4 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
Viewing 1-25 of 61 product results



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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).