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TGFB2 / TGF Beta2
transforming growth factor, beta 2
TGFB2 / TGF Beta2 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.
| Gene Name: | transforming growth factor, beta 2 |
| Family/Subfamily: | TGF beta , not assigned-TGF beta |
| Synonyms: | TGFB2, BSC-1 cell growth inhibitor, Cetermin, G-TSF, LDS4, Polyergin, TGF-beta-2, TGF Beta2, TGF-beta2 |
| Target Sequences: | NM_003238 NP_003229.1 P61812 |
Publications (1)
1
Prolyl hydroxylase 2 silencing enhances the paracrine effects of mesenchymal stem cells on necrotizing enterocolitis in an NF-?B-dependent mechanism. Hao Chen , Haifeng Zhang , Yue Zheng , Xiaohui Min , Yujun Luo, Weijie Zhou, Faxin Ma, Jinliang Li, Quan Lu, Chen Zhang, Huihua Cai, Weihong Sha. Cell death & disease. 2020 Mar;11:188. [Full Text Article]
[PubMed:32179740]
[PMC:PMC7075868]
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TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (aa277-306) Antibody
IHC, IHC-P, WB
Unconjugated
200 µl/$460
TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Bovine, Rat, Pig, Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (aa143-192) (Biotin) Antibody
Rabbit, Mouse, Dog, Sheep, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
E. coli
His
14.2 kDa
10 µg/$299; 50 µg/$552; 100 µg/$882; 200 µg/$1,080; 1 mg/$2,261; 500 µg/$1,775; 5 mg/$3,851; 2 mg/$2,453
Neuroscience
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (aa361-410) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$460
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
Sandwich
96-Well Strip Plate
Bovine
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$669
HEK 293 Cells
None
Biologically active
Less than 0.1 ng/µg of protein (less than 1EU/µg).
25.0 kDa
2 µg/$268; 10 µg/$349
E. coli
His, N-Terminal
16.5 kDa
10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334
Neuroscience
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$460
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (aa304-413) Antibody
Mouse, Human
ELISA, IHC-P, WB
Unconjugated
50 µg/$460
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (aa303-414) Antibody
Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal (220ct16.4.3.1) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal (Biotin) (220ct16.4.3.1) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal (FITC) (220ct16.4.3.1) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal (PE) (220ct16.4.3.1) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal (APC) (220ct16.4.3.1) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal (Azide-free) (HRP) (220ct16.4.3.1) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
Neuroscience
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC-P, WB
Unconjugated
100 µl/$485
Sandwich
96-Well Microplate
Mouse
31.2 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$699
Sandwich
96-Well Microplate
Human
15 - 6000 pg/ml
Colorimetric - 450nm (TMB)
Cell Culture Supernatants, Plasma, Serum
1 Plate/$534
Sandwich
12 x 8-Well Microstrips
Human
32 - 2000 pg/ml
Colorimetric - 450nm (TMB)
Cell Lysates, Plasma, Serum
1 Plate/$534
Sandwich
96-Well Strip Plate
Mouse
15.6 - 1000 pg/ml
Colorimetric - 450nm (TMB)
Plasma, Serum
1 Plate/$585
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