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TGFB2 / TGF Beta2

transforming growth factor, beta 2

TGFB2 / TGF Beta2 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.

Gene Name: transforming growth factor, beta 2
Family/Subfamily: TGF beta , not assigned-TGF beta
Synonyms: TGFB2, BSC-1 cell growth inhibitor, Cetermin, G-TSF, LDS4, Polyergin, TGF-beta-2, TGF Beta2, TGF-beta2
Target Sequences: NM_003238 NP_003229.1 P61812

Publications (1)

1
Prolyl hydroxylase 2 silencing enhances the paracrine effects of mesenchymal stem cells on necrotizing enterocolitis in an NF-?B-dependent mechanism. Hao Chen , Haifeng Zhang , Yue Zheng , Xiaohui Min , Yujun Luo, Weijie Zhou, Faxin Ma, Jinliang Li, Quan Lu, Chen Zhang, Huihua Cai, Weihong Sha. Cell death & disease. 2020 Mar;11:188. [Full Text Article] [PubMed:32179740] [PMC:PMC7075868]

☰ Filters
Products
Antibodies (63)
Primary (63)
TGFB2 / TGF Beta2 (63)
Human (45)
Mouse (20)
Rat (22)
Bat (3)
Bovine (12)
Chicken (1)
Chimpanzee (3)
Cow (8)
Dog (3)
Gibbon (3)
Horse (3)
Monkey (3)
Pig (4)
Rabbit (3)
Sheep (3)
IHC (26)
IHC-P (15)
WB (55)
ELISA (19)
ICC (5)
IF (7)
Peptide-ELISA (3)
rabbit (55)
mouse (7)
goat (1)
Product Group
IHCPlus (3)
PathPlus Neuro (3)
IgG (20)
IgG1,k (7)
monoclonal mc (7)
polyclonal pc (56)
220ct16.4.3.1 (6)
APC (3)
APC Conjugated (4)
Azide-free (1)
Biotin Conjugated (7)
Cy3 Conjugated (3)
Cy7 Conjugated (3)
FITC Conjugated (7)
HRP Conjugated (7)
PE Conjugated (4)
Unconjugated (28)
aa303-414 (16)
aa331-442 (8)
aa143-192 (4)
aa304-413 (4)
N-Terminus (3)
C-Terminus (1)
Internal Region (1)
Leu388 (1)
aa277-306 (1)
aa361-410 (1)
No (63)
TGFB2 / TGF Beta2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
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TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (aa277-306) Antibody
IHC, IHC-P, WB
Unconjugated
200 µl/$460
TGFB2 / TGF Beta2 Antibody - TGFB2 Antibody immunohistochemistry of formalin-fixed and paraffin-embedded human breast carcinoma followed by peroxidase-conjugated secondary antibody and DAB staining.
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TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
400 µl/$393
TGFB2 / TGF Beta2 Antibody - Immunohistochemical analysis of TGF beta 2 staining in human lung cancer formalin fixed paraffin embedded tissue section. The section was pre-treated using heat mediated antigen retrieval with sodium citrate buffer (pH 6.0). The section was then incubated with the antibody at room temperature and detected using an HRP conjugated compact polymer system. DAB was used as the chromogen. The section was then counterstained with hematoxylin and mounted with DPX.
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TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Bovine, Rat, Pig, Mouse, Human
IHC, IHC-P, WB
Unconjugated
100 µl/$299
TGFB2 / TGF Beta2 Antibody - TGFB2 antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (aa143-192) Antibody
Mouse, Human
WB
Unconjugated
100 µl/$424
TGFB2 / TGF Beta2 Antibody - TGFB2 antibody Western blot of NCI-H226 cell lysate. This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (aa143-192) (Biotin) Antibody
Rabbit, Mouse, Dog, Sheep, Bovine, Pig, Horse, Bat, Rat, Chimpanzee, Gibbon, Human, Monkey
WB
Biotin Conjugated
100 µl/$469
TGFB2 / TGF Beta2 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Neuroscience
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (aa361-410) Antibody
Mouse, Rat, Human
IHC, IHC-P, Peptide-ELISA
Unconjugated
50 µl/$460
TGFB2 / TGF Beta2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
TGFB2 / TGF Beta2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (HRP) Antibody
Human
ELISA, IHC, IHC-P, WB
HRP Conjugated
50 µg/$294; 100 µg/$360
TGFB2 / TGF Beta2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (Biotin) Antibody
Human
ELISA, IHC, IHC-P, WB
Biotin Conjugated
50 µg/$294; 100 µg/$360
TGFB2 / TGF Beta2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE).  This image was taken for the unconjugated form of this product. Other forms have not been tested.
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TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (FITC) Antibody
Human
ELISA, IHC, IHC-P, WB
FITC Conjugated
50 µg/$294; 100 µg/$360
TGFB2 / TGF Beta2 Antibody - Human Adrenal: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Neuroscience
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P
Unconjugated
50 µl/$460
TGFB2 / TGF Beta2 Antibody - Human Placenta: Formalin-Fixed, Paraffin-Embedded (FFPE)
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TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (aa304-413) Antibody
Mouse, Human
ELISA, IHC-P, WB
Unconjugated
50 µg/$460
TGFB2 / TGF Beta2 Antibody - Western blot of recombinant TGFB2.
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TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (aa303-414) Antibody
Human
WB
Unconjugated
100 µl/$299; 200 µl/$337; 500 µl/$463; 1 ml/$527; 2 ml/$682; 5 ml/$1,141
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TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal (220ct16.4.3.1) Antibody
Human
ELISA, IF, IHC, WB
Unconjugated
200 µl/$734
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TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal (Biotin) (220ct16.4.3.1) Antibody
Human
ELISA, ICC, IF, IHC, WB
Biotin Conjugated
200 µl/$952
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TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal (FITC) (220ct16.4.3.1) Antibody
Human
ELISA, ICC, IF, IHC, WB
FITC Conjugated
200 µl/$952
Select
TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal (PE) (220ct16.4.3.1) Antibody
Human
ELISA, ICC, IF, IHC, WB
PE Conjugated
200 µl/$952
Select
TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal (APC) (220ct16.4.3.1) Antibody
Human
ELISA, ICC, IF, IHC, WB
APC Conjugated
200 µl/$952
Select
TGFB2 / TGF Beta2 Mouse anti-Human Monoclonal (Azide-free) (HRP) (220ct16.4.3.1) Antibody
Human
ELISA, ICC, IF, IHC, WB
HRP Conjugated, Azide-free
200 µl/$952
TGFB2 / TGF Beta2 Antibody - Human Prostate: Formalin-Fixed, Paraffin-Embedded (FFPE)
Select
Neuroscience
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC-P, WB
Unconjugated
100 µl/$485
TGFB2 / TGF Beta2 Antibody
Select
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
TGFB2 / TGF Beta2 Antibody - Immunohistochemistry of paraffin-embedded Human lung using TGFB2 Polycloanl Antibody at dilution of 1:200.
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TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
20 µl/$250; 60 µl/$286; 120 µl/$349; 200 µl/$439
Select
TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
ELISA, IHC, WB
Unconjugated
50 µg/$440; 100 µg/$480
TGFB2 / TGF Beta2 Antibody - 1:100 staining human lung carcinoma tissue by IHC-P. The tissue was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The tissue was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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TGFB2 / TGF Beta2 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TGFB2 / TGF Beta2 Antibody - Immunohistochemistry of paraffin-embedded Human kidney using TGFB2 Polycloanl Antibody at dilution of 1:200.
Select
TGFB2 / TGF Beta2 Rabbit anti-Mouse Polyclonal Antibody
Mouse, Rat, Human
IHC
Unconjugated
20 µl/$250; 60 µl/$286; 120 µl/$349; 200 µl/$439
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The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).