TGFB2 / TGF Beta2

transforming growth factor, beta 2

TGFB2 / TGF Beta2 is a member of the transforming growth factor beta (TGFB) family of cytokines, which are multifunctional peptides that regulate proliferation, differentiation, adhesion, migration, and other functions in many cell types by transducing their signal through combinations of transmembrane type I and type II receptors (TGFBR1 and TGFBR2) and their downstream effectors, the SMAD proteins. Disruption of the TGFB/SMAD pathway has been implicated in a variety of human cancers. The encoded protein is secreted and has suppressive effects of interleukin-2 dependent T-cell growth. Translocation t(1;7)(q41;p21) between this gene and HDAC9 is associated with Peters' anomaly, a congenital defect of the anterior chamber of the eye. The knockout mice lacking this gene show perinatal mortality and a wide range of developmental, including cardiac, defects. Alternatively spliced transcript variants encoding different isoforms have been identified.

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Products

Proteins (19)

Type

Over-Expression Lysate (4)

Recombinant (15)

Target

TGFB2 / TGF Beta2 (19)

Publications

No (18)

Yes (1)

Tag

6His, N-terminus (1)

GST (1)

His (1)

His, N-Terminal (1)

His-T7 (1)

Myc-DDK (Flag) (5)

Species

Bovine (1)

Human (12)

Mouse (3)

Rat (1)

Source

293T Cells (2)

CHO Cells (1)

E. coli (4)

HEK 293 Cells (4)

Human Cells (4)

Mammalian Cells (3)

Wheat Germ Extract (1)

Purification

Purified (5)

Low Endotoxin Level

Low endotoxin level (9)

Biologically Active

Biologically active (5)

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Rat TGFB2 / TGF Beta2 Protein (Recombinant His) (aa331-442) - LS-G11803

(4.0) Rating

(1) Publication(s)

Source:

E. coli

Tag:

His

Molecular Weight:

14.2 kDa

Price:

10 µg/$299; 50 µg/$552; 100 µg/$882; 200 µg/$1,080; 1 mg/$2,261; 500 µg/$1,775; 5 mg/$3,851; 2 mg/$2,453

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Human TGFB2 / TGF Beta2 Protein (Recombinant) - LS-G42

Source:

HEK 293 Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

25.0 kDa

Price:

2 µg/$268; 10 µg/$349

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Bovine TGFB2 / TGF Beta2 Protein (Recombinant His, N-Terminal) (aa303-414) - LS-G11797

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

16.5 kDa

Price:

10 µg/$291; 50 µg/$502; 100 µg/$802; 200 µg/$1,002; 1 mg/$2,144; 500 µg/$1,668; 5 mg/$3,501; 2 mg/$2,334

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Human TGFB2 / TGF Beta2 Protein (Recombinant Myc-DDK (Flag)) (Full Length) - LS-G67172

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.6 kDa

Price:

20 µg/$1,107

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Human TGFB2 / TGF Beta2 Protein (Recombinant His-T7) (aa303-414) - LS-G11799

Source:

E. coli

Tag:

His-T7

Molecular Weight:

16.7 kDa

Price:

10 µg/$284; 50 µg/$460; 100 µg/$735; 200 µg/$917; 1 mg/$2,037; 500 µg/$1,571; 5 mg/$3,207; 2 mg/$2,225

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Human TGFB2 / TGF Beta2 Protein (Recombinant GST) (Full Length) - LS-G30690

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

74.1 kDa

Price:

2 µg/$439

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Human TGFB2 / TGF Beta2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79280

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.4 kDa

Price:

20 µg/$150

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Human TGFB2 / TGF Beta2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G79281

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.6 kDa

Price:

20 µg/$150

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TGFB2 / TGF Beta2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G100000

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

47.6 kDa

Price:

100 µg/$494

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TGFB2 / TGF Beta2 Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G125474

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

50.4 kDa

Price:

100 µg/$494

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Human TGFB2 / TGF Beta2 Protein (Recombinant) - LS-G137644

Source:

CHO Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 112 amino acid recombinant protein has a predicted molecular mass of approximately 12.7 kD. The DTT-reduced protein migrates at approximately 14 kD and non-reduced protein migrates at 28-30 kD by SDS-PAGE. The N-terminal amino acid is Alanine.

Price:

5 µg/$468

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Human TGFB2 / TGF Beta2 Protein (Recombinant 6His, N-terminus) (aa304-413) - LS-G56572

Source:

E. coli

Tag:

6His, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Human TGFB2 / TGF Beta2 Protein (Recombinant) (Full Length) - LS-G137074

Source:

Mammalian Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

12.7 kDa

Price:

50 µg/$698; 10 µg/$356; 1 mg/$3,932; 500 µg/$2,459

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Mouse TGFB2 / TGF Beta2 Protein (Recombinant) (Ala303-Ser414) - LS-G140669

Source:

Mammalian Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

12.7 kDa

Price:

10 µg/$317; 50 µg/$524

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Human TGFB2 / TGF Beta2 Protein (Recombinant) (Ala303-Ser414) - LS-G140431

Source:

Mammalian Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

12.7 kDa

Price:

10 µg/$317; 50 µg/$524

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Human TGFB2 / TGF Beta2 Protein (Recombinant) (Ala303-Ser414) - LS-G145591

Source:

Human Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

12.7 kDa

Price:

10 µg/$402; 1 mg/$3,780; 50 µg/$879

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Mouse TGFB2 / TGF Beta2 Protein (Recombinant) (Ala303-Ser414) - LS-G145592

Source:

Human Cells

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

12.7 kDa

Price:

10 µg/$402; 1 mg/$3,780; 50 µg/$879

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Human TGFB2 / TGF Beta2 Protein (Recombinant) (Ala303-Ser414) - LS-G40037

Source:

Human Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

12.7kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,869; 1 mg/$2,991

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Mouse TGFB2 / TGF Beta2 Protein (Recombinant) (Ala303-Ser414) - LS-G40091

Source:

Human Cells

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

12.7kD

Price:

10 µg/$321; 50 µg/$534; 500 µg/$1,869; 1 mg/$2,991

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