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TP63 / p63
tumor protein p63
Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. Isoform 2 activates RIPK4 transcription. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. Involved in Notch signaling by probably inducing JAG1 and JAG2. Plays a role in the regulation of epithelial morphogenesis. The ratio of DeltaN-type and TA*-type isoforms may govern the maintenance of epithelial stem cell compartments and regulate the initiation of epithelial stratification from the undifferentiated embryonal ectoderm. Required for limb formation from the apical ectodermal ridge. Activates transcription of the p21 promoter.
| Gene Name: | tumor protein p63 |
| Family/Subfamily: | Apoptosis |
| Synonyms: | TP63, B(p51B), CUSP, AIS, EEC3, KET, NBP, OFC8, p73L, p73H, RHS, SHFM4, LMS, TP53CP, Tumor protein 63, Tumor protein p53-like, Tumor protein p73-like, TP73L, p51, B(p51A), Tumor protein p63, p40, p53CP, p63, TP53L |
| Target Sequences: | NM_003722 NP_003713.3 Q9H3D4 |
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Antibodies
(101)
Type
Primary
(101)
Target
TP63 / p63
(101)
Reactivity
Human
(78)
Mouse
(30)
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(22)
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(2)
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(4)
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(4)
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(5)
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(36)
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(28)
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(76)
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(2)
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(20)
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(13)
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(15)
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(8)
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(7)
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rabbit
(68)
mouse
(31)
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(2)
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(3)
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(1)
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(1)
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(50)
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(9)
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(1)
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(5)
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(5)
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(2)
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(1)
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monoclonal mc
(34)
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(67)
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(1)
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(1)
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(1)
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(1)
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(2)
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(1)
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(2)
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(2)
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(2)
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(3)
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(1)
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(1)
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(1)
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(1)
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(1)
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(1)
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(2)
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(4)
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(93)
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(10)
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(8)
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(4)
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(4)
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(3)
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(3)
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(2)
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(2)
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(2)
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(2)
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(1)
aa125-415
(1)
aa319-410
(1)
aa424-446
(1)
aa623-641
(1)
aa662-680
(1)
pSer160/Ser162
(1)
Publications
No
(101)
TP63 / p63 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
IF, IHC, IHC-P, Peptide-ELISA, WB
Unconjugated
50 µl/$460
Cancer Pathology
Cancer
TP63 / p63 Mouse anti-Human Monoclonal Antibody
Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
TP63 / p63 Mouse anti-Human Monoclonal (Ready-to-Use) (4A4) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$402
TP63 / p63 Mouse anti-Human Monoclonal (aa1-205) Antibody
IF, IHC, IHC-Fr, IHC-P, IP, WB
Unconjugated
500 µl/$541
TP63 / p63 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Chicken, Bovine, Mouse, Dog, Rat, Pig, Human, Monkey
ICC, IF, IHC, WB
Unconjugated
100 µl/$299
TP63 / p63 Mouse anti-Human Monoclonal (aa67-84) (87C553) Antibody
WB
Unconjugated
0.1 mg/$386
TP63 / p63 Rabbit anti-Human Monoclonal (C-Terminus) Antibody
ICC, IP, WB
Unconjugated
100 µl/$465
TP63 / p63 Mouse anti-Human Monoclonal (Carrier-free) (OTI4E7) Antibody
Human
IHC, WB
Unconjugated, Carrier-free
100 µg/$511
TP63 / p63 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
ICC, WB
Unconjugated
100 µl/$688
TP63 / p63 Rabbit anti-Human Monoclonal (DBR16.1) Antibody
Human
IHC
Unconjugated
0.1 ml/$290; 0.5 ml/$527; 1 ml/$829
TP63 / p63 Rabbit anti-Human Monoclonal (Ready-to-Use) (EP174) Antibody
Human
IHC-Fr, IHC-P
Unconjugated, Ready-to-Use
3 ml/$422; 7 ml/$593; 15 ml/$993
TP63 / p63 Rabbit anti-Human Polyclonal (aa125-415) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µl/$450
TP63 / p63 Rabbit anti-Human Polyclonal (aa664-680) Antibody
Chicken, Sheep, Bovine, Rabbit, Dog, Guinea pig, Pig, Horse, Bat, Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$575
TP63 / p63 Rabbit anti-Human Polyclonal (aa664-680) Antibody
Chicken, Sheep, Bovine, Rabbit, Guinea pig, Pig, Horse, Bat, Human, Monkey
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
TP63 / p63 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human, Monkey
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
TP63 / p63 Mouse anti-Human Monoclonal (aa1-205) Antibody
IF, IHC, IHC-P, IP, WB
Unconjugated
500 µl/$490
TP63 / p63 Mouse anti-Human Monoclonal (aa1-205) (11E308) Antibody
Mouse, Rat, Human
ICC, IHC, IP, WB
Unconjugated
500 µl/$579
TP63 / p63 Rabbit anti-Human Polyclonal (aa623-641) Antibody
ICC, IHC, IHC-P, WB
Unconjugated
200 µg/$511
TP63 / p63 Rabbit anti-Human Polyclonal (aa424-446) Antibody
ICC, IHC, IHC-P, WB
Unconjugated
200 µg/$511
TP63 / p63 Rabbit anti-Human Polyclonal (aa311-680) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
100 µg/$575
TP63 / p63 Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IF, IHC, WB
Unconjugated
20 µl/$275; 100 µl/$389
TP63 / p63 Rabbit anti-Human Polyclonal (Asn662) Antibody
Mouse, Rat, Human
IF, IHC, WB
Unconjugated
50 µl/$321; 100 µl/$403
TP63 / p63 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ICC, IF, WB
Unconjugated
50 µg/$305; 100 µg/$357
TP63 / p63 Mouse anti-Human Monoclonal (400000) Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, WB
Unconjugated
100 µl/$459
TP63 / p63 Mouse anti-Human Monoclonal Antibody
Mouse, Rat, Human, Monkey
ELISA, IHC, WB
Unconjugated
50 µg/$332; 100 µg/$404; 200 µg/$505
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product results
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