TSLP

thymic stromal lymphopoietin

TSLP is a hemopoietic cytokine proposed to signal through a heterodimeric receptor complex composed of the thymic stromal lymphopoietin receptor and the IL-7R alpha chain. It mainly impacts myeloid cells and induces the release of T cell-attracting chemokines from monocytes and enhances the maturation of CD11c(+) dendritic cells. The protein promotes T helper type 2 (TH2) cell responses that are associated with immunity in various inflammatory diseases, including asthma, allergic inflammation and chronic obstructive pulmonary disease. The protein is therefore considered a potential therapeutic target for the treatment of such diseases. Alternative splicing of this gene results in multiple transcript variants.

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Products

Proteins (27)

Type

Over-Expression Lysate (4)

Recombinant (23)

Target

TSLP (27)

Application

Bind (1)

ELISA (1)

Func (1)

SDS-PAGE (2)

Publications

No (27)

Tag

10His, C-terminus (2)

6His, C-terminus (1)

6His, N-terminus (1)

6His-SUMO, N-terminus (1)

Fc, C-terminus (2)

GST (1)

GST, N-terminus (1)

His (2)

His, N-Terminal (1)

His,C-terminus (2)

His-GST (1)

His-T7 (1)

Myc-DDK (Flag) (4)

more less

Species

Cynomolgus (1)

Human (18)

Mouse (5)

Rat (1)

Source

293T Cells (2)

E. coli (13)

HEK 293 Cells (4)

Human (2)

Human Cells (2)

Mammalian Cells (2)

Wheat Germ Extract (2)

Purification

Purified (11)

Low Endotoxin Level

Low endotoxin level (14)

Biologically Active

Biologically active (6)

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Rat TSLP Protein (Recombinant His, N-Terminal) (Leu75-Ser196) - LS-G13659

Source:

E. coli

Tag:

His, N-Terminal

Molecular Weight:

15.4 kDa

Price:

10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119

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Mouse TSLP Protein (Recombinant His) (Met1-Glu140) - LS-G98865

Source:

Human Cells

Tag:

His

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

15.4 kDa

Price:

100 µg/$767; 1 mg/$3,472

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Human TSLP Protein (Recombinant His) - LS-G3164

Source:

E. coli

Tag:

His

Price:

20 µg/$361; 100 µg/$739; 4 µg/$261

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Human TSLP Protein (Recombinant His,C-terminus) (Met1-Gln159) - LS-G141247

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

SDS-PAGE

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The recombinant human TSLP consists of 142 amino acids and predicts a molecular mass of 16.2 kDa.

Price:

100 µg/$480; 500 µg/$1,460

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Cynomolgus TSLP Protein (Recombinant 6His, C-terminus) - LS-G146310

Source:

E. coli

Tag:

6His, C-terminus

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

16.2 kDa

Price:

10 µg/$289; 50 µg/$446

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Mouse TSLP Protein (Recombinant Fc, C-terminus) (Tyr20-Glu140) - LS-G40027

Source:

Human Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

41.1kD

Price:

10 µg/$277; 50 µg/$395; 500 µg/$1,203; 1 mg/$1,627

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Human TSLP Protein (Recombinant) - LS-G326

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 0.1 ng/µg of protein (less than 1EU/µg).

Molecular Weight:

15.0 kDa

Price:

2 µg/$268; 10 µg/$349

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Human TSLP Protein (Recombinant) (aa29-159) - LS-G5758

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Molecular Weight:

15.1 kDa

Price:

10 µg/$388; 100 µg/$1,466; 500 µg/$3,025

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Human TSLP Protein (Recombinant GST, N-terminus) (aa1-60) - LS-G63442

Source:

Wheat Germ Extract

Tag:

GST, N-terminus

Price:

10 µg/$479; 25 µg/$670

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Mouse TSLP Protein (Recombinant His-GST) (aa21-138) - LS-G13663

Source:

E. coli

Tag:

His-GST

Molecular Weight:

46.0 kDa

Price:

10 µg/$281; 50 µg/$442; 100 µg/$705; 200 µg/$882; 1 mg/$1,989; 500 µg/$1,529; 5 mg/$3,081; 2 mg/$2,176

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Human TSLP Protein (Recombinant His-T7) (aa29-159) - LS-G24278

Source:

E. coli

Tag:

His-T7

Molecular Weight:

17.8 kDa

Price:

10 µg/$273; 50 µg/$392; 100 µg/$625; 200 µg/$782; 1 mg/$1,847; 500 µg/$1,404; 5 mg/$2,807; 2 mg/$2,029

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Human TSLP Protein (Recombinant GST) (Full Length) - LS-G35929

Source:

Wheat Germ Extract

Tag:

GST

Molecular Weight:

33.5 kDa

Price:

2 µg/$439

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Mouse TSLP Protein (Recombinant His,C-terminus) (Met1-Glu140) - LS-G48892

Source:

HEK 293 Cells

Tag:

His,C-terminus

Application:

Bind ELISA Func SDS-PAGE

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

The secreted recombinant mouse TSLP comprises 132 amino acids and has a calculated molecular mass of 15.4 kDa. As a result of glycosylation, the apparent molecular mass of the recombinant protein is approximately 22-27 kDa in SDS-PAGE under reducing conditions.

Price:

100 µg/$480; 1 mg/$2,003

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Human TSLP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92904

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18 kDa

Price:

20 µg/$150

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Human TSLP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G92906

Source:

293T Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

7.9 kDa

Price:

20 µg/$150

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TSLP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G108452

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

18 kDa

Price:

100 µg/$494

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Human TSLP Protein (Recombinant 10His, C-terminus) - LS-G146027

Source:

Human

Tag:

10His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

16.3 kDa

Price:

10 µg/$290; 50 µg/$446

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Human TSLP Protein (Recombinant 10His, C-terminus) - LS-G146102

Source:

Human

Tag:

10His, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

16.1 kDa

Price:

10 µg/$290; 50 µg/$446

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Human TSLP Protein (Recombinant) - LS-G137657

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 0.01 ng/µg (determined by LAL method).

Molecular Weight:

The 132 amino acid recombinant protein has a predicted molecular mass of approximately 15 kD. The DTT-reduced protein migrates at approximately 17 kD and non-reduced protein at approximately 18 kD by SDS-PAGE. The N-terminal amino acid is Met.

Price:

10 µg/$352; 25 µg/$474; 100 µg/$1,177; 500 µg/$2,235

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Human TSLP Protein (Recombinant) - LS-G145666

Source:

E. coli

Tag:

None

Biological Activity:

Biologically active

Endotoxin Level:

Less than 1 EU/µg (determined by LAL method).

Molecular Weight:

15.1 kDa

Price:

10 µg/$372; 1 mg/$5,021

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TSLP Protein (Over-Expression Lysate Myc-DDK (Flag)) (Full Length) - LS-G107284

Source:

HEK 293 Cells

Tag:

Myc-DDK (Flag)

Molecular Weight:

7.9 kDa

Price:

100 µg/$494

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Human TSLP Protein (Recombinant 6His, N-terminus) (aa29-159) - LS-G57062

Source:

Mammalian Cells

Tag:

6His, N-terminus

Price:

100 µg/$1,009; 20 µg/$431; 1 mg/$3,451

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Human TSLP Protein (Recombinant 6His-SUMO, N-terminus) (aa29-159) - LS-G56604

Source:

E. coli

Tag:

6His-SUMO, N-terminus

Price:

1 mg/$1,355; 100 µg/$420; 20 µg/$323

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Mouse TSLP Protein (Recombinant Fc, C-terminus) (Tyr20-Glu140) - LS-G139286

Source:

Mammalian Cells

Tag:

Fc, C-terminus

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

41.1 kDa

Price:

10 µg/$277; 50 µg/$389

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Human TSLP Protein (Recombinant) (Tyr29-Gln159) - LS-G140415

Source:

E. coli

Tag:

None

Endotoxin Level:

Less than 1.0 EU/µg protein (determined by LAL method).

Molecular Weight:

15.1 kDa

Price:

10 µg/$317; 50 µg/$524

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