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VTN / Vitronectin

vitronectin

Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.

Gene Name: vitronectin
Family/Subfamily: Matrix Protein , not assigned-Other
Synonyms: VTN, Epibolin, Serum-spreading factor, VNT, S-protein, Somatomedin B, V75, VN, Complement S-protein, Serum spreading factor, Vitronectin
Target Sequences: NM_000638 NP_000629.3 P04004

Publications (4)

1
Structure of human Vitronectin C-terminal domain and interaction with Yersinia pestis outer membrane protein Ail. Shin K, Lechtenberg BC, Fujimoto LM, Yao Y, Bartra SS, Plano GV, Marassi FM. Science advances. 2019 September;5: [Full Text Article] [PubMed:31535027] [PMC:PMC6739113] Related Antibodies: LS-C407672.
2
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. Jiasheng Zhang , Dmitry Velmeshev , Kei Hashimoto , Yu-Hsin Huang , Jeffrey W Hofmann, Xiaoyu Shi, Jiapei Chen, Andrew M Leidal, Julian G Dishart, Michelle K Cahill, Kevin W Kelley, Shane A Liddelow, William W Seeley, Bruce L Miller, Tobias C Walther, Robert V Farese Jr, J Paul Taylor, Erik M Ullian, Bo Huang, Jayanta Debnath, Torsten Wittmann, Arnold R Kriegstein, Eric J Huang. Nature. 2020 August; [Full Text Article] [PubMed:32866962] [PMC:PMC7746606]
3
Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production. Yukitaka Ito, Sou Nakamura, Naoshi Sugimoto, Tomohiro Shigemori, Yoshikazu Kato, Mikiko Ohno, Shinya Sakuma, Keitaro Ito, Hiroki Kumon, Hidenori Hirose, Haruki Okamoto, Masayuki Nogawa, Mio Iwasaki, Shunsuke Kihara, Kosuke Fujio, Takuya Matsumoto, Natsumi Higashi, Kazuya Hashimoto, Akira Sawaguchi, Ken-Ichi Harimoto, Masato Nakagawa, Takuya Yamamoto, Makoto Handa, Naohide Watanabe, Eiichiro Nishi, Fumihito Arai, Satoshi Nishimura, Koji Eto. Cell. 2018 July;174:636-648.e18. [Full Text Article] [PubMed:30017246]
4
TAZ-CAMTA1 and YAP-TFE3 alter the TAZ/YAP transcriptome by recruiting the ATAC histone acetyltransferase complex. Nicole Merritt , Keith Garcia , Dushyandi Rajendran, Zhen-Yuan Lin, Xiaomeng Zhang, Katrina A Mitchell, Nicholas Borcherding, Colleen Fullenkamp, Michael S Chimenti, Anne-Claude Gingras, Kieran F Harvey, Munir R Tanas. eLife. 2021 April;10:e62857. [Full Text Article] [PubMed:33913810] [PMC:PMC8143797] Related Antibodies: LS-B2118.
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☰ Filters
Products
Proteins (19)
Over-Expression Lysate (2)
Recombinant (17)
VTN / Vitronectin (19)
Animal-free (1)
No (19)
6His, C-terminus (3)
6His, N-terminus (1)
GST (1)
His (4)
His, N-Terminal (4)
His,C-terminus (1)
Myc-DDK (Flag) (3)
Human (14)
Mouse (3)
Rat (1)
293T Cells (1)
E. coli (9)
HEK 293 Cells (5)
Human (1)
Human Cells (1)
Mammalian Cells (1)
Wheat Germ Extract (1)
Purified (6)
Low endotoxin level (6)
Animal-free (1)
Select
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
53.35kD
10 µg/$233; 50 µg/$269; 500 µg/$519; 1 mg/$725
VTN / Vitronectin Protein - Recombinant Vitronectin By SDS-PAGE
Select
E. coli
His
9.7 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
VTN / Vitronectin Protein - Recombinant  Vitronectin By SDS-PAGE
Select
E. coli
His, N-Terminal
47.2 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
VTN / Vitronectin Protein
Select
E. coli
His
11.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
Select
E. coli
6His, N-terminus
18 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
VTN / Vitronectin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
293T Cells
Myc-DDK (Flag)
54.34 kDa
20 µg/$150
Select
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
54.2 kDa
100 µg/$383; 1 mg/$1,797
VTN / Vitronectin Protein - Recombinant Human Vitronectin/VTN (N-Truncated, C-6His)
Select
Human
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
48.3 kDa
10 µg/$235; 50 µg/$283
VTN / Vitronectin Protein
Select
HEK 293 Cells
His, N-Terminal
52.2 kDa
50 µg/$677
VTN / Vitronectin Protein - Recombinant Vitronectin (VTN) by SDS-PAGE
Select
E. coli
His, N-Terminal
55.0kDa
10 µg/$278; 50 µg/$422; 200 µg/$842; 100 µg/$672; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
VTN / Vitronectin Protein - Western validation with an anti-DDK antibody * L: Control HEK293 lysate R: Over-expression lysate
Select
HEK 293 Cells
Myc-DDK (Flag)
54.34 kDa
100 µg/$494
VTN / Vitronectin Protein - 12.5% SDS-PAGE of human VTN stained with Coomassie Blue
Select
Wheat Germ Extract
GST
80.7 kDa
10 µg/$479; 25 µg/$670
VTN / Vitronectin Protein - Purified recombinant protein VTN was analyzed by SDS-PAGE gel and Coomassie Blue Staining
Select
HEK 293 Cells
Myc-DDK (Flag)
52.2 kDa
20 µg/$1,107
Select
HEK 293 Cells
None
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
100 µg/$282; 500 µg/$364
VTN / Vitronectin Protein
Select
E. coli
None
47.5 kDa
50 µg/$419
VTN / Vitronectin Protein - Recombinant Vitronectin (VTN) by SDS-PAGE
Select
E. coli
His, N-Terminal
30.5kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
VTN / Vitronectin Protein
Select
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
Select
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
53.4 kDa
10 µg/$233; 50 µg/$269
Select
E. coli
327 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
36.08 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).