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VTN / Vitronectin
vitronectin
Vitronectin is a cell adhesion and spreading factor found in serum and tissues. Vitronectin interact with glycosaminoglycans and proteoglycans. Is recognized by certain members of the integrin family and serves as a cell-to-substrate adhesion molecule. Inhibitor of the membrane-damaging effect of the terminal cytolytic complement pathway.Somatomedin-B is a growth hormone-dependent serum factor with protease-inhibiting activity.
| Gene Name: | vitronectin |
| Family/Subfamily: | Matrix Protein , not assigned-Other |
| Synonyms: | VTN, Epibolin, Serum-spreading factor, VNT, S-protein, Somatomedin B, V75, VN, Complement S-protein, Serum spreading factor, Vitronectin |
| Target Sequences: | NM_000638 NP_000629.3 P04004 |
Publications (4)
1
Structure of human Vitronectin C-terminal domain and interaction with Yersinia pestis outer membrane protein Ail. Shin K, Lechtenberg BC, Fujimoto LM, Yao Y, Bartra SS, Plano GV, Marassi FM. Science advances. 2019 September;5: [Full Text Article]
[PubMed:31535027]
[PMC:PMC6739113]
Related Antibodies: LS-C407672.
2
Neurotoxic microglia promote TDP-43 proteinopathy in progranulin deficiency. Jiasheng Zhang , Dmitry Velmeshev , Kei Hashimoto , Yu-Hsin Huang , Jeffrey W Hofmann, Xiaoyu Shi, Jiapei Chen, Andrew M Leidal, Julian G Dishart, Michelle K Cahill, Kevin W Kelley, Shane A Liddelow, William W Seeley, Bruce L Miller, Tobias C Walther, Robert V Farese Jr, J Paul Taylor, Erik M Ullian, Bo Huang, Jayanta Debnath, Torsten Wittmann, Arnold R Kriegstein, Eric J Huang. Nature. 2020 August; [Full Text Article]
[PubMed:32866962]
[PMC:PMC7746606]
3
Turbulence Activates Platelet Biogenesis to Enable Clinical Scale Ex Vivo Production. Yukitaka Ito, Sou Nakamura, Naoshi Sugimoto, Tomohiro Shigemori, Yoshikazu Kato, Mikiko Ohno, Shinya Sakuma, Keitaro Ito, Hiroki Kumon, Hidenori Hirose, Haruki Okamoto, Masayuki Nogawa, Mio Iwasaki, Shunsuke Kihara, Kosuke Fujio, Takuya Matsumoto, Natsumi Higashi, Kazuya Hashimoto, Akira Sawaguchi, Ken-Ichi Harimoto, Masato Nakagawa, Takuya Yamamoto, Makoto Handa, Naohide Watanabe, Eiichiro Nishi, Fumihito Arai, Satoshi Nishimura, Koji Eto. Cell. 2018 July;174:636-648.e18. [Full Text Article]
[PubMed:30017246]
☰ Filters
Products
Proteins
(19)
Type
Over-Expression Lysate
(2)
Recombinant
(17)
Target
VTN / Vitronectin
(19)
Format
Animal-free
(1)
Publications
No
(19)
Tag
6His, C-terminus
(3)
6His, N-terminus
(1)
GST
(1)
His
(4)
His, N-Terminal
(4)
His,C-terminus
(1)
Myc-DDK (Flag)
(3)
Species
Human
(14)
Mouse
(3)
Rat
(1)
Source
293T Cells
(1)
E. coli
(9)
HEK 293 Cells
(5)
Human
(1)
Human Cells
(1)
Mammalian Cells
(1)
Wheat Germ Extract
(1)
Purification
Purified
(6)
Low Endotoxin Level
Low endotoxin level
(6)
Animal-free
Animal-free
(1)
Human Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
53.35kD
10 µg/$233; 50 µg/$269; 500 µg/$519; 1 mg/$725
E. coli
His
9.7 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
E. coli
His, N-Terminal
47.2 kDa
10 µg/$284; 50 µg/$462; 100 µg/$737; 200 µg/$922; 1 mg/$2,042; 500 µg/$1,577; 5 mg/$3,221; 2 mg/$2,231
E. coli
His
11.8 kDa
10 µg/$278; 50 µg/$422; 100 µg/$672; 200 µg/$842; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
E. coli
6His, N-terminus
18 kDa
10 µg/$265; 50 µg/$315; 100 µg/$365
293T Cells
Myc-DDK (Flag)
54.34 kDa
20 µg/$150
HEK 293 Cells
His,C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
54.2 kDa
100 µg/$383; 1 mg/$1,797
Human
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
48.3 kDa
10 µg/$235; 50 µg/$283
HEK 293 Cells
His, N-Terminal
52.2 kDa
50 µg/$677
E. coli
His, N-Terminal
55.0kDa
10 µg/$278; 50 µg/$422; 200 µg/$842; 100 µg/$672; 1 mg/$1,934; 500 µg/$1,480; 5 mg/$2,941; 2 mg/$2,119
HEK 293 Cells
Myc-DDK (Flag)
54.34 kDa
100 µg/$494
Wheat Germ Extract
GST
80.7 kDa
10 µg/$479; 25 µg/$670
HEK 293 Cells
Myc-DDK (Flag)
52.2 kDa
20 µg/$1,107
HEK 293 Cells
None
Less than 0.01 ng/µg of protein (Less than 0.1 EU/µg).
100 µg/$282; 500 µg/$364
E. coli
His, N-Terminal
30.5kDa
10 µg/$283; 50 µg/$452; 200 µg/$902; 100 µg/$722; 1 mg/$2,016; 500 µg/$1,553; 5 mg/$3,151; 2 mg/$2,204
E. coli
His
50 µg/$411; 250 µg/$985; 10 µg/$276
Mammalian Cells
6His, C-terminus
Less than 1.0 EU/µg protein (determined by LAL method).
53.4 kDa
10 µg/$233; 50 µg/$269
E. coli
327 AA
His
Less than 0.1 EU/µg protein (determined by LAL method).
36.08 kDa
10 mg/$4,268; 5 mg/$3,201; 1 mg/$1,868; 0.5 mg/$1,475; 200 µg/$1,103; 100 µg/$756; 50 µg/$531
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