Corporate Headquarters
Vector Laboratories, Inc.
6737 Mowry Ave
Newark, CA 94560
United States
XCR1 is a chemokine receptor belonging to the G protein-coupled receptor superfamily. The family members are characterized by the presence of 7 transmembrane domains and numerous conserved amino acids. This receptor is most closely related to RBS11 and the MIP1-alpha/RANTES receptor. It transduces a signal by increasing the intracellular calcium ions level. The viral macrophage inflammatory protein-II is an antagonist of this receptor and blocks signaling. Two alternatively spliced transcript variants encoding the same protein have been found for this gene.
Gene Name: | chemokine (C motif) receptor 1 |
Family/Subfamily: | GPCR , Chemokine |
Synonyms: | XCR1, CCXCR1, Chemokine (C motif) receptor 1, Chemokine XC receptor 1, G protein-coupled receptor 5, GPR5, Lptn receptor, Lymphotactin receptor, XC chemokine receptor 1, G-protein coupled receptor 5 |
Target Sequences: | NM_005283 NP_005274.1 P46094 |
If you do not find the reagent or information you require, please contact Customer.Support@LSBio.com to inquire about additional products in development.