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| Catalog Number | Size | Price |
|---|---|---|
| LS-C83427-100 | 100 µg | $563 |
Monoclonal Mouse anti‑Human BRCA1 Antibody (aa762‑1315, IHC, WB) LS‑C83427
Monoclonal Mouse anti‑Human BRCA1 Antibody (aa762‑1315, IHC, WB) LS‑C83427
Antibody:
BRCA1 Mouse anti-Human Monoclonal (aa762-1315) Antibody
Application:
IHC, WB, IP
Reactivity:
Human
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
BRCA1 Mouse anti-Human Monoclonal (aa762-1315) Antibody
Application:
IHC, WB, IP
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
BRCA1 antibody LS-C83427 is an unconjugated mouse monoclonal antibody to human BRCA1 (aa762-1315). Validated for IHC, IP and WB.
Target
Human BRCA1
Synonyms
BRCA1 | BROVCA1 | BRCC1 | Breast cancer 1, early onset | PPP1R53 | PSCP | PNCA4 | RING finger protein 53 | RNF53 | BRCAI | Breast cancer 1 early onset | IRIS
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Unmodified
Immunogen
GST fusion protein expressed in E. coli corresponding to aa 762-1315 of full-length BRCA1.
Epitope
aa762-1315
Specificity
Recognizes full-length BRCA1, a 220 kD nuclear phosphoprotein, and does not recognize the ~exon 11 splice variant. In a high proportion of breast and ovarian cancer cell lines, BRCA1 aberrantly mislocates to the cytoplasm. Its usefulness to monitor functional inactivation of BRCA1 in sporadic breast cancers is under active investigation.
Applications
- IHC (1 - 10 µg/ml)
- Western blot (1 - 10 µg/ml)
- Immunoprecipitation (1 - 10 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, pH 7.4
Storage
Short term: store at 4°C. Long term: aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About BRCA1
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Featured Products
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Species:
Human
Applications:
Immunofluorescence, Western blot, Immunoprecipitation
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/4/2024
Date Requested: 11/4/2024
