Human CD3

Rat

Human (tested or 100% immunogen sequence identity)

IgG1 Monoclonal

CD3-12

FITC

Protein G purified

Unmodified

Synthetic peptide sequence derived from cytoplasmic epitope of CD3 (Glu-Arg-Pro-Pro-Val-Pro-Asn-Pro-Asp-Tyr-Glu-Pro-Cys). Percent identity by BLAST analysis: Chimpanzee, Gorilla, Ferret, Panda, Bovine, Dog, Cat, Opossum, Turkey, Chicken, Lizard (83%).

Raised against a peptide representing an invariant cytoplasmic sequence within the CD3epsilon chain recognizes human CD3epsilon. CD3 is a multimeric protein complex composed of four distinct polypeptide chains (epsilon, gamma, delta, zeta) that assemble and function as three pairs of dimers (epsilon-gamma, epsilon-delta, zeta-zeta;). The CD3 complex serves as a T cell co-receptor that associates non-covalently with the T cell receptor (TCR) ; ;. CD3 is a defining feature of cells belonging to the T cell lineage and can therefore be used as T cell marker. Ashas been specifically raised against an epitope within the epsilon peptide chain, highly conserved among species clone CD3-12 has a very broad species cross-reactivity for the CD3 marker. ;.

• Flow Cytometry (1:5 - 1:10)

The applications listed have been tested for the unconjugated form of this product. Other forms have not been tested.

PBS, 0.09% Sodium Azide, 1% BSA

Store at 4°C or at -20°C. Store undiluted. Avoid freeze-thaw cycles. Protect from light. Microcentrifugation recommended if solution contains precipitate.

For research use only. Intended for use by laboratory professionals.

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