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| Catalog Number | Size | Price |
|---|---|---|
| LS-C31836-100 | 100 µl (0.5 mg/ml) | $397 |
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2 of 2
Polyclonal Rabbit anti‑Human HSPB1 / HSP27 Antibody (C‑Terminus, IHC, WB) LS‑C31836
Polyclonal Rabbit anti‑Human HSPB1 / HSP27 Antibody (C‑Terminus, IHC, WB) LS‑C31836
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Specifications
Description
HSP27 antibody LS-C31836 is an unconjugated rabbit polyclonal antibody to human HSP27 (HSPB1) (C-Terminus). Validated for IHC and WB. Cited in 6 publications.
Target
Human HSPB1 / HSP27
Synonyms
HSPB1 | 28 kDa heat shock protein | Heat shock 27 kDa protein | Heat shock 27kD protein 1 | Heat shock 27kDa protein 1 | HSP27 | HSP28 | HSP 27 | Hsp25 | SRP27 | Stress-responsive protein 27 | CMT2F | Heat shock 27 kd protein | Heat shock protein beta-1 | HMN2B | HS.76067
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG
Polyclonal
Purification
Protein A purified
Modifications
Unmodified
Immunogen
Synthetic peptide from C-Terminus of human HSPB1 (P04792, NP_001531). Percent identity by BLAST analysis: Human, Chimpanzee, Gorilla, Monkey (100%); Marmoset (84%).
Epitope
C-Terminus
Specificity
Human HSPB1
Applications
- IHC
- IHC - Paraffin
- Western blot (1.25 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.09% sodium azide, 2% sucrose
Storage
Short term: Store at 2-8°C. Long term: Aliquot and store at -20°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About HSPB1 / HSP27
LSBio Ratings
HSPB1 / HSP27 Antibody (C-Terminus) for IHC, WB/Western LS-C31836 has an LSBio Rating of
Publications (4.5)
Learn more about The LSBio Ratings Algorithm
Publications (6)
Rationally Repurposing Ruxolitinib (Jakafi (®)) as a Solid Tumor Therapeutic. Tavallai M, Booth L, Roberts JL, Poklepovic A, Dent P. Frontiers in oncology. 2016 6:142. (WB; Human)
Multi-kinase inhibitors can associate with heat shock proteins through their NH2-termini by which they suppress chaperone function. Booth L, Shuch B, Albers T, Roberts JL, Tavallai M, Proniuk S, Zukiwski A, Wang D, Chen CS, Bottaro D, Ecroyd H, Lebedyeva IO, Dent P. Oncotarget. 2016 7:12975-96. (WB; Human)
[Pemetrexed + Sorafenib] lethality is increased by inhibition of ERBB1/2/3-PI3K-NF?B compensatory survival signaling. Booth L, Roberts JL, Tavallai M, Chuckalovcak J, Stringer DK, Koromilas AE, Boone DL, McGuire WP, Poklepovic A, Dent P. Oncotarget. 2016 7:23608-32. (WB; Human)
Multi-kinase inhibitors interact with sildenafil and ERBB1/2/4 inhibitors to kill tumor cells in vitro and in vivo. Booth L, Albers T, Roberts JL, Tavallai M, Poklepovic A, Lebedyeva IO, Dent P. Oncotarget. 2016 7:40398-40417. (WB; Human)
PDE5 inhibitors enhance the lethality of pemetrexed through inhibition of multiple chaperone proteins and via the actions of cyclic GMP and nitric oxide. Booth L, Roberts JL, Poklepovic A, Gordon S, Dent P. Oncotarget. 2017 8:1449-1468. (WB; Human)
The HDAC inhibitor AR42 interacts with pazopanib to kill trametinib/dabrafenib-resistant melanoma cells in vitro and in vivo. Booth L, Roberts JL, Sander C, Lee J, Kirkwood JM, Poklepovic A, Dent P. Oncotarget. 2017 8:16367-16386. (WB; Human)
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, Immunoprecipitation, ELISA
Species:
Turkey, Human
Applications:
IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot
Species:
Human, Monkey, Bovine, Guinea pig, Pig
Applications:
Western blot
Species:
Human, Chimpanzee, Mouse, Rat, Sheep, Chicken
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Immunoprecipitation, Flow Cytometry, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/24/2024
Date Requested: 11/24/2024
