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| Catalog Number | Size | Price |
|---|---|---|
| LS-B4-50 | 50 µg (0.5 mg/ml) | $485 |
IHC‑plus™ Polyclonal Goat anti‑Human ABCC4 / MRP4 Antibody (aa1312‑1325, IHC) LS‑B4
IHC‑plus™ Polyclonal Goat anti‑Human ABCC4 / MRP4 Antibody (aa1312‑1325, IHC) LS‑B4
Note: This antibody replaces LS-C342869, LS-C72797, LS-C124148
Antibody:
ABCC4 / MRP4 Goat anti-Human Polyclonal (aa1312-1325) Antibody
Application:
IHC, IHC-P, Peptide-ELISA
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
ABCC4 / MRP4 Goat anti-Human Polyclonal (aa1312-1325) Antibody
Application:
IHC, IHC-P, Peptide-ELISA
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
MRP4 antibody LS-B4 is an unconjugated goat polyclonal antibody to MRP4 (ABCC4) (aa1312-1325) from human. It is reactive with human and monkey. Validated for IHC and Peptide-ELISA. Tested on 20 paraffin-embedded human tissues. Cited in 3 publications.
Target
Human ABCC4 / MRP4
Synonyms
ABCC4 | EST170205 | MOAT-B | Multidrug resistance protein 4 | MOATB | MRP4
Host
Goat
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Purified from goat serum by ammonium sulphate precipitation followed by antigen affinity chromatography using the immunizing peptide.
Modifications
Unmodified
Immunogen
Peptide with sequence CNGQPSTLTIFETAL, from the C-Terminus of protein sequence according to NP_005836.2.
Epitope
aa1312-1325
Specificity
Human ABCC4 / MRP4. This antibody is expected to recognize isoform 1 (NP_005836.2) only.
Applications
- IHC
- IHC - Paraffin (2.5 µg/ml)
- Peptide Enzyme-Linked Immunosorbent Assay (1:1000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: LS-B4 was validated for use in immunohistochemistry on a panel of 21 formalin-fixed, paraffin-embedded (FFPE) human tissues after heat induced antigen retrieval in pH 6.0 citrate buffer. After incubation with the primary antibody, slides were incubated with biotinylated secondary antibody, followed by alkaline phosphatase-streptavidin and chromogen. The stained slides were evaluated by a pathologist to confirm staining specificity. The optimal working concentration for LS-B4 was determined to be 2.5 ug/ml.
Presentation
TBS, pH 7.3, 0.02% Sodium Azide, 0.5% BSA
Storage
Aliquot and store at -20°C. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About ABCC4 / MRP4
Validation
Anti-ABCC4 / MRP4 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
Anti-ABCC4 / MRP4 antibody IHC of human prostate. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
See More About...
LSBio Ratings
IHC-plus™ ABCC4 / MRP4 Antibody (aa1312-1325) for IHC LS-B4 has an LSBio Rating of
Publications (4.2)
Laboratory Validation Score (4)
Learn more about The LSBio Ratings Algorithm
Publications (3)
Aryl hydrocarbon receptor and NF-E2-related factor 2 are key regulators of human MRP4 expression. Xu S, Weerachayaphorn J, Cai SY, Soroka CJ, Boyer JL. American journal of physiology. Gastrointestinal and liver physiology. 2010 299:G126-35.
Nuclear factor-E2-related factor 2 is a major determinant of bile acid homeostasis in the liver and intestine. Weerachayaphorn J, Mennone A, Soroka CJ, Harry K, Hagey LR, Kensler TW, Boyer JL. American journal of physiology. Gastrointestinal and liver physiology. 2012 302:G925-36. (WB; Mouse)
Transporter function and cyclic AMP turnover in normal colonic mucosa from patients with and without colorectal neoplasia. Kleberg K, Jensen GM, Christensen DP, Lundh M, Grunnet LG, Knuhtsen S, Poulsen SS, Hansen MB, Bindslev N. BMC gastroenterology. 2012 12:78. (IHC; Human)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Western blot, ELISA
Species:
Human
Applications:
IHC, IHC - Frozen, ICC, Western blot, Flow Cytometry
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
