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Catalog Number	Size	Price
LS-C70920-100	100 µg	$907

Monoclonal Rat anti‑Mouse IL6R / IL6 Receptor Antibody (Extracellular Domain, WB) LS‑C70920

Name: Anti-IL6R / IL6 Receptor Antibody | Rat anti-Mouse Monoclonal | LSBio
Brand: Lifespan BioSciences
SKU: LS-C70920-100
Price: 907.0000 USD
Availability: InStock
Rating: 4 (1 reviews)

(4.0) Rating

Submit Review (1) Publication(s) LSBio Guarantee

Antibody:

IL6R / IL6 Receptor Rat anti-Mouse Monoclonal (Extracellular Domain) Antibody

Application:

WB, ELISA

Reactivity:

Mouse

Format:

Unconjugated, Unmodified

$907

LS-C70920-100

Toll Free North America

(800) 227-6666

For Research Use Only

Specifications Publications Reviews Featured Products Request SDS/MSDS

Overview

Antibody:

IL6R / IL6 Receptor Rat anti-Mouse Monoclonal (Extracellular Domain) Antibody

Application:

WB, ELISA

Reactivity:

Mouse

Format:

Unconjugated, Unmodified

Specifications

Description

IL6 Receptor antibody LS-C70920 is an unconjugated rat monoclonal antibody to mouse IL6 Receptor (IL6R) (Extracellular Domain). Validated for ELISA and WB. Cited in 1 publication.

(1) Publication(s)

Target

Mouse IL6R / IL6 Receptor

Synonyms

See All IL6R / IL6 Receptor Antibodies

Host

Rat

Reactivity

Mouse (tested or 100% immunogen sequence identity)

Clonality

IgG1 Monoclonal

Conjugations

Unconjugated

Purification

Protein G purified

Modifications

Unmodified

Immunogen

NS0-derived rmIL-6Ralpha extracellular domain (aa 20-357) P22272

Epitope

Extracellular Domain

Specificity

Recognizes mouse IL-6Ralpha. In direct ELISAs and Western Blots, this antibody does not cross-react with rhIL-6R.

Applications

Western blot
ELISA

Usage

Western Blot: This antibody can be used at 1-2 ug/mL with the appropriate secondary reagents to detect mouse IL-6 R. Using a colorimetric detection system, the detection limit for rmIL-6 R is approximately 25 ng/lane under non-reducing and reducing conditions. Chemiluminescent detection will increase sensitivity by 5 to 50 fold. Direct ELISA: This antibody can be used at 0.5-1.0 ug/mL with the appropriate secondary reagents to detect mouse IL-6 R. The detection limit for rmIL-6 R is approximately 5 ng/well.

Presentation

Lyophilized from PBS, pH 7.4, 5% Trehalose

Reconstitution

Reconstitute in 200 ul sterile PBS

Storage

Store at -20°C lyophilized. Once reconstituted: Store at -20°C. Aliquot to avoid freeze-thaw cycles.

Restrictions

For research use only. Intended for use by laboratory professionals.

Guarantee

This antibody carries the LSBio 100% Guarantee.

LSBio Guarantee

About IL6R / IL6 Receptor

Uniprot: P08887 NCBI: NM_000565 NP_000556.1

LSBio Ratings

IL6R / IL6 Receptor Antibody (Extracellular Domain) for WB/Western, ELISA LS-C70920 has an LSBio Rating of

(4.0) Rating

Publications (4)

Learn more about The LSBio Ratings Algorithm

Publications (1)

Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130. Wang X, Miller EB, Goswami M, Zhang P, Ronning KE, Karlen SJ, Zawadzki RJ, Pugh EN Jr, Burns ME. Journal of neuroinflammation. 2017 14:121. (WB; Mouse)

Full Text Article PubMed: 28645275 PMC: PMC5481880

Submit a Publication for LS-C70920