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IL6R / IL6 Receptor
interleukin 6 receptor
IL6R / IL6 Receptor is a subunit of the interleukin 6 (IL6) receptor complex. Interleukin 6 is a potent pleiotropic cytokine that regulates cell growth and differentiation and plays an important role in the immune response. The IL6 receptor is a protein complex consisting of this protein and interleukin 6 signal transducer (IL6ST/GP130/IL6-beta), a receptor subunit also shared by many other cytokines. Dysregulated production of IL6 and this receptor are implicated in the pathogenesis of many diseases, such as multiple myeloma, autoimmune diseases and prostate cancer. Alternatively spliced transcript variants encoding distinct isoforms have been reported. A pseudogene of this gene is found on chromosome 9.
| Gene Name: | interleukin 6 receptor |
| Family/Subfamily: | Interleukin |
| Synonyms: | IL6R, CD126, gp80, IL-6R subunit alpha, IL-6R-alpha, IL-6RA, IL6Q, IL-6 receptor subunit alpha, IL-6R 1, IL-6R-1, Interleukin 6 receptor, Membrane glycoprotein 80, CD126 antigen, IL6RA, IL6RQ |
| Target Sequences: | NM_000565 NP_000556.1 P08887 |
Publications (2)
1
Interleukin 6 regulates psoriasiform inflammation-associated thrombosis. Wang Y, Golden JB, Fritz Y, Zhang X, Diaconu D, Camhi MI, Gao H, Dawes SM, Xing X, Ganesh SK, Gudjonsson JE, Simon DI, McCormick TS, Ward NL. JCI insight. 2016 1:e89384. (IHC-P; Human)
[Full Text Article]
[PubMed:27942589]
[PMC:PMC5135273]
Related Antibodies: LS-B6362.
2
Rapid monocyte infiltration following retinal detachment is dependent on non-canonical IL6 signaling through gp130. Wang X, Miller EB, Goswami M, Zhang P, Ronning KE, Karlen SJ, Zawadzki RJ, Pugh EN Jr, Burns ME. Journal of neuroinflammation. 2017 14:121. (WB; Mouse)
[Full Text Article]
[PubMed:28645275]
[PMC:PMC5481880]
Related Antibodies: LS-C70920.
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Antibodies
(132)
Type
Primary
(132)
Target
IL6R / IL6 Receptor
(132)
Reactivity
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(32)
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(18)
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(24)
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(30)
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(101)
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(14)
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(52)
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aa192-458
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(1)
aa246-260
(1)
aa379-419
(1)
Publications
No
(130)
Yes
(2)
IL6R / IL6 Receptor Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µl/$460
IL6R / IL6 Receptor Rat anti-Mouse Monoclonal (Extracellular Domain) Antibody
Mouse
ELISA, WB
Unconjugated
100 µg/$907
IL6R / IL6 Receptor Mouse anti-Human Monoclonal (B-R6) Antibody
Human
ELISA, Flo, IF, IHC, IHC-Fr, IP
Unconjugated
0.1 mg/$385
IL6R / IL6 Receptor Mouse anti-Human Monoclonal (OTI2F4) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
100 µl/$450
IL6R / IL6 Receptor Rabbit anti-Rat Polyclonal (aa19-108) Antibody
Rat
WB
Unconjugated
100 µl/$312; 200 µl/$355; 500 µl/$500; 1 ml/$573; 2 ml/$780; 5 ml/$1,268
IL6R / IL6 Receptor Rabbit anti-Rat Polyclonal (aa19-108) (Biotin) Antibody
Rat
WB
Biotin Conjugated
100 µl/$322; 200 µl/$370; 500 µl/$529; 1 ml/$614; 2 ml/$846; 5 ml/$1,395
IL6R / IL6 Receptor Rabbit anti-Human Polyclonal (aa216-356) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µl/$460
IL6R / IL6 Receptor Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, ICC
Unconjugated
100 µg/$848
IL6R / IL6 Receptor Mouse anti-Human Monoclonal (B-R6) Antibody
Human
ELISA, Flo, Func, IHC, IHC-Fr, IP
Unconjugated
100 µg/$597
IL6R / IL6 Receptor Mouse anti-Human Monoclonal Antibody
Human
ELISA, Flo, IHC, IHC-Fr, IP
Unconjugated
100 µg/$801
IL6R / IL6 Receptor Rabbit anti-Rat Polyclonal (aa214-348) Antibody
Rat
WB
Unconjugated
100 µl/$312; 200 µl/$355; 500 µl/$500; 1 ml/$573; 2 ml/$780; 5 ml/$1,268
IL6R / IL6 Receptor Rabbit anti-Human Polyclonal Antibody
Mouse, Human
IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
IL6R / IL6 Receptor Rabbit anti-Human Polyclonal (aa221-270) Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
IL6R / IL6 Receptor Mouse anti-Human Monoclonal (17506) Antibody
Human
ELISA, Flo, Neut, WB
Unconjugated
100 µg/$962
IL6R / IL6 Receptor Rat anti-Mouse Monoclonal (Extracellular Domain) Antibody
Mouse
Flo, ICC
Unconjugated
500 µg/$1,089
IL6R / IL6 Receptor Rabbit anti-Human Polyclonal (aa23-371) Antibody
Human
ELISA, IP, WB
Unconjugated
100 µg/$341
IL6R / IL6 Receptor Mouse anti-Human Monoclonal Antibody
Human
ELISA
Unconjugated
100 µl/$412
IL6R / IL6 Receptor Human anti-Human Recombinant Monoclonal (IL-6 receptor) (rhPM-1 (Tocilizumab)) Antibody
Human
ELISA, Inhb
Unconjugated
0.2 mg/$540
IL6R / IL6 Receptor Rabbit anti-Mouse Polyclonal Antibody
Mouse
ELISA, Flo, ICC, IF
Unconjugated
20 µl/$271; 100 µl/$412
IL6R / IL6 Receptor Rabbit anti-Mouse Polyclonal (aa205-347) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
IL6R / IL6 Receptor Rabbit anti-Mouse Polyclonal (aa52-204) Antibody
Mouse
WB
Unconjugated
100 µl/$306; 200 µl/$347; 500 µl/$484; 1 ml/$553; 2 ml/$737; 5 ml/$1,206
IL6R / IL6 Receptor Mouse anti-Human Monoclonal (APC) Antibody
Human
Flo
APC Conjugated
100 Tests/$884
IL6R / IL6 Receptor Rabbit anti-Human Polyclonal (aa1-365) Antibody
Human
ELISA
Unconjugated
100 µl/$412
IL6R / IL6 Receptor Goat anti-Mouse Polyclonal (aa246-260) Antibody
Mouse
Peptide-ELISA
Unconjugated
100 µg/$401
IL6R / IL6 Receptor Rabbit anti-Human Polyclonal (aa379-419) Antibody
Human
WB
Unconjugated
10 µg/$318; 100 µg/$470
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of 132
product results
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