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| Catalog Number | Size | Price |
|---|---|---|
| LS-C392287-100 | 100 µg (1 mg/ml) | $574 |
Monoclonal Mouse anti‑Human KRT8 / CK8 / Cytokeratin 8 Antibody (clone SPM538, Azide‑free,BSA‑free, IHC, IF) LS‑C392287
Monoclonal Mouse anti‑Human KRT8 / CK8 / Cytokeratin 8 Antibody (clone SPM538, Azide‑free,BSA‑free, IHC, IF) LS‑C392287
Antibody:
KRT8 / CK8 / Cytokeratin 8 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPM538) Antibody
Application:
IHC, IHC-P, IF, Flo
Reactivity:
Human, Rat, Zebrafish
Format:
Unconjugated, Azide-free, BSA-free
Other formats:
Toll Free North America
(800) 227-6666
(800) 227-6666For Research Use Only
Overview
Antibody:
KRT8 / CK8 / Cytokeratin 8 Mouse anti-Human Monoclonal (Azide-free, BSA-free) (SPM538) Antibody
Application:
IHC, IHC-P, IF, Flo
Reactivity:
Human, Rat, Zebrafish
Format:
Unconjugated, Azide-free, BSA-free
Other formats:
Specifications
Description
Cytokeratin 8 antibody LS-C392287 is an unconjugated mouse monoclonal antibody to Cytokeratin 8 (KRT8 / CK8) from human. It is reactive with human, rat and zebrafish. Validated for Flow, IF and IHC.
Target
Human KRT8 / CK8 / Cytokeratin 8
Synonyms
KRT8 | CARD2 | CK-8 | CYK8 | Cytokeratin-8 | CK8 | K2C8 | K8 | KO | Keratin-8 | Type-II keratin Kb8 | Cytokeratin 8 | Keratin 8
Host
Mouse
Reactivity
Human, Rat, Zebrafish
(tested or 100% immunogen sequence identity)
Clonality
IgG1
Monoclonal
Clone
SPM538
Conjugations
Unconjugated
Purification
Protein G purified
Modifications
Azide-free, BSA-free.
Also available Unmodified.
Immunogen
Cytoskeleton preparation containing keratin 8.
Specificity
Human KRT8 / CK8 / Cytokeratin 8
Applications
- IHC
- IHC - Paraffin (1 - 2 µg/ml)
- Immunofluorescence (1 - 2 µg/ml)
- Flow Cytometry (0.5 - 1 µg/10E6 cells)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
The applications listed have been tested for the unmodified form of this product. Other forms have not been tested. Cytokeratin 8 (CK8) belongs to the type II (or B or basic) subfamily of high molecular weight cytokeratins and exists in combination with cytokeratin 18 (CK18). CK8 is primarily found in the non-squamous epithelia and is present in majority of adenocarcinomas and ductal carcinomas. It is absent in squamous cell carcinomas. Hepatocellular carcinomas are defined by the use of antibodies that recognize only cytokeratin 8 and 18. CK8 exists on several types of normal and neoplastic epithelia, including many ductal and glandular epithelia such as colon, stomach, small intestine, trachea, and esophagus as well as in transitional epithelium. Anti-CK8 does not react with skeletal muscle or nerve cells. Epithelioid sarcoma, chordoma, and adamantinoma show strong positivity corresponding to that of simple epithelia (with antibodies against CK8, CK18 and CK19). Reportedly, anti-CK8 is useful for the differentiation of lobular ('ring-like, perinuclear') from ductal ('peripheral-predominant') carcinoma of the breast.
Presentation
1X PBS
Storage
Store at 2°C to 8°C.
Restrictions
For research use only. Intended for use by laboratory professionals.
About KRT8 / CK8 / Cytokeratin 8
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Bovine, Rabbit, Sheep, Porcine
Applications:
IHC, IHC - Paraffin, ICC, Western blot, Immunoprecipitation
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, ELISA
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Species:
Human, Monkey, Bovine, Guinea pig, Hamster, Pig
Applications:
IHC, Western blot
Species:
Human, Rat, Rabbit
Applications:
IHC, IHC - Paraffin, IHC - Frozen, ICC, Western blot, Flow Cytometry
Species:
Human, Mouse
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Western blot, Peptide Enzyme-Linked Immunosorbent Assay
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/22/2024
Date Requested: 11/22/2024
