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| Catalog Number | Size | Price |
|---|---|---|
| LS-B16202-0.05 | 0.05 ml | $460 |
PathPlus™ Monoclonal Mouse anti‑Human ACTH Antibody (IHC) LS‑B16202
PathPlus™ Monoclonal Mouse anti‑Human ACTH Antibody (IHC) LS‑B16202
Note: This antibody replaces LS-C312218
Antibody:
ACTH Mouse anti-Human Monoclonal Antibody
Application:
IHC-P, IHC-Fr
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Toll Free North America
206-374-1102
206-374-1102For Research Use Only
Overview
Antibody:
ACTH Mouse anti-Human Monoclonal Antibody
Application:
IHC-P, IHC-Fr
Reactivity:
Human
Format:
Unconjugated, Unmodified
Other formats:
Specifications
Description
Adrenocorticotropic hormone (ACTH) is a polypeptide tropic hormone. Part of the hypothalamic-pituitary-adrenal axis, it stimulates the secretion of steroid hormones from the adrenal cortex. It also exerts effects on osteoblasts. ACTH is expressed and secreted by corticotropes in the anterior pituitary gland and is also expressed at lower levels in the brain, adrenal medulla, skin, and placenta and at higher levels in ACTH-secreting tumors. Staining is used to identify ACTH-secreting tumors such as pituitary adenomas and nonpituitary tumors such as pancreatic neuroendocrine neoplasms and pancreatic acinar cell carcinomas and pancreatoblastomas.
References: J Mol Endocrinol. 2016;56(4):T135-T156. doi: 10.1530/JME-15-0257;Microsc Res Tech. 2003;61(3):308-314. PMID: 12768546;J Neuroendocrinol. 2008;20(6):692-699. doi: 10.1111/j.1365-2826.2008.01709.x;Am J Surg Pathol. 2015;39(3):374-382. doi: 10.1097/PAS.0000000000000340;Ann N Y Acad Sci. 2009;1163:93-100. doi: 10.1111/j.1749-6632.2009.04434.x.
Host
Mouse
Reactivity
Human
(tested or 100% immunogen sequence identity)
Clonality
IgG1,k
Monoclonal
Conjugations
Unconjugated
Purification
Ig fraction
Modifications
Unmodified.
Also available Ready-to-Use.
Applications
- IHC - Paraffin (1:50)
- IHC - Frozen (1:250 - 1:1000)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Usage
Immunohistochemistry: Paraffin and frozen. Control tissue: Normal Pituitary. Localization: Cytoplasmic.
Presentation
Filter sterilized and diluted in buffer, pH 7.5, BSA, Sodium Azide
Storage
Store at 2-8°C. Avoid freeze/thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Validation
Human Pituitary: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Pituitary: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ ACTH Antibody for IHC LS-B16202 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Rat
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human, Rat
Applications:
IHC, IHC - Paraffin, ICC, ELISA
Species:
Human, Mouse, Rat, Pig
Applications:
IHC, IHC - Paraffin, IHC - Frozen, ELISA
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 5/14/2024
Date Requested: 5/14/2024
