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| Catalog Number | Size | Price |
|---|---|---|
| LS-A28-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human C3AR / C3a Receptor Antibody (Extracellular Domain, IHC) LS‑A28
PathPlus™ Polyclonal Rabbit anti‑Human C3AR / C3a Receptor Antibody (Extracellular Domain, IHC) LS‑A28
Antibody:
C3AR / C3a Receptor Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
C3AR / C3a Receptor Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Complement component 3a receptor 1 (C3AR1) mediates the effects of the inflammatory mediator anaphylatoxin C3a, which is released during complement activation. C3AR1 stimulates chemotaxis, granule enzyme release, and superoxide anion production. It also regulates glial cell activation, may be involved in the pathogenesis of asthma, and may promote cell repair.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human C3AR / C3a Receptor
Synonyms
C3AR1 | AZ3B | C3AR | C3R1 | C3a receptor | C3a-R | HNFAG09 | Anaphylatoxin c3a receptor | C3a anaphylatoxin receptor
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 20 amino acid peptide from 2nd extracellular domain of human C3a Receptor. Percent identity with other species by BLAST analysis: Human (100%); Gorilla, Marmoset (95%); Orangutan, Gibbon (90%).
Epitope
Extracellular Domain
Specificity
Human C3a Receptor. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except ADRA1A (40%).
Applications
- IHC
- IHC - Paraffin (17.3 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About C3AR / C3a Receptor
Validation
Brain Alzheimer's, microglia
Brain Alzheimer's, microglia
Brain Hypothalamus Choroid Plexus
Brain Hypothalamus Choroid Plexus
Allergic rhinitis, eosinophils
Allergic rhinitis, eosinophils
Anti-C3AR / C3a Receptor antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 17.3 ug/ml.
Anti-C3AR / C3a Receptor antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 17.3 ug/ml.
Anti-C3AR / C3a Receptor antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 17.3 ug/ml.
Anti-C3AR / C3a Receptor antibody IHC of human small intestine. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 17.3 ug/ml.
See More About...
LSBio Ratings
PathPlus™ C3AR / C3a Receptor Antibody (Extracellular Domain) for IHC LS-A28 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Rat
Applications:
IHC, IHC - Frozen, Flow Cytometry
Species:
Rat
Applications:
IHC, IHC - Frozen, Flow Cytometry
Species:
Rat
Applications:
IHC, IHC - Frozen, Flow Cytometry
Reactivity:
Mouse
Range:
0.156-10 ng/ml
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/25/2024
Date Requested: 11/25/2024
