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| Catalog Number | Size | Price |
|---|---|---|
| LS-A1389-50 | 50 µg (1 mg/ml) | $460 |
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PathPlus™ Polyclonal Rabbit anti‑Human CCR3 Antibody (C‑Terminus, IHC) LS‑A1389
PathPlus™ Polyclonal Rabbit anti‑Human CCR3 Antibody (C‑Terminus, IHC) LS‑A1389
Antibody:
CCR3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Overview
Antibody:
CCR3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey
Format:
Unconjugated, Unmodified
Specifications
Description
Chemokine (C-C motif) receptor 3 (CCR3) belongs to family 1 of the G protein-coupled receptors. CCR3 is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human CCR3
Synonyms
CCR3 | C-C chemokine receptor type 3 | B-chemokine receptor | CD193 | CD193 antigen | Chemokine c-c motif receptor 3 | C-C chemokine receptor 3 | CKR3 | CC-CKR-3 | CCR-3 | CMKBR3 | Eosinophil eotaxin receptor | Eotaxin receptor | C-C CKR-3 | CC chemokine receptor 3
Host
Rabbit
Reactivity
Human, Monkey
(tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 16 amino acid peptide from C-Terminus of human CCR3. Percent identity with other species by BLAST analysis: Human, Gorilla, Monkey (100%); Gibbon (94%); Marmoset, Dog, Rabbit (88%); Mouse, Bovine, Hamster, Horse (81%).
Epitope
C-Terminus
Specificity
Human CCR3. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except CGNL1 (44%).
Applications
- IHC
- IHC - Paraffin (8 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About CCR3
Validation
Tonsil, Immunoblasts
Tonsil, Immunoblasts
Brain, Alzheimer's disease, senile plaque
Brain, Alzheimer's disease, senile plaque
Anti-CCR3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR3 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR3 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR3 antibody IHC of human nasal mucosa, allergic rhinitis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-CCR3 antibody IHC of human nasal mucosa, allergic rhinitis. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
See More About...
LSBio Ratings
PathPlus™ CCR3 Antibody (C-Terminus) for IHC LS-A1389 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
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Featured Products
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin, Flow Cytometry
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Mouse, Rat
Applications:
IHC, IHC - Paraffin, Western blot
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 12/20/2024
Date Requested: 12/20/2024
