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CCR3

chemokine (C-C motif) receptor 3

CCR3 is a receptor for C-C type chemokines. It belongs to family 1 of the G protein-coupled receptors. This receptor binds and responds to a variety of chemokines, including eotaxin (CCL11), eotaxin-3 (CCL26), MCP-3 (CCL7), MCP-4 (CCL13), and RANTES (CCL5). It is highly expressed in eosinophils and basophils, and is also detected in TH1 and TH2 cells, as well as in airway epithelial cells. This receptor may contribute to the accumulation and activation of eosinophils and other inflammatory cells in the allergic airway. It is also known to be an entry co-receptor for HIV-1. This gene and seven other chemokine receptor genes form a chemokine receptor gene cluster on the chromosomal region 3p21. Alternatively spliced transcript variants have been described.

Gene Name: chemokine (C-C motif) receptor 3
Family/Subfamily: GPCR , Chemokine
Synonyms: CCR3, C-C chemokine receptor type 3, B-chemokine receptor, CD193, CD193 antigen, Chemokine c-c motif receptor 3, C-C chemokine receptor 3, CKR3, CC-CKR-3, CCR-3, CMKBR3, Eosinophil eotaxin receptor, Eotaxin receptor, C-C CKR-3, CC chemokine receptor 3
Target Sequences: NM_001837 NP_001828.1 P51677

Publications (1)

1
CCR7 is involved in the migration of neutrophils to lymph nodes. Beauvillain C, Cunin P, Doni A, Scotet M, Jaillon S, Loiry ML, Magistrelli G, Masternak K, Chevailler A, Delneste Y, Jeannin P. Blood. 2011 117:1196-204. [PubMed:21051556] Related Antibodies: LS-C41095.

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rabbit (35)
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No (48)
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CCR3 Antibody - Anti-CCR3 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody dilution 5 ug/ml.
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CCR3 Goat anti-Mouse Polyclonal (aa5-28) Antibody
Mouse, Human
ICC, IHC, IHC-P, WB
Unconjugated
50 µg/$505
CCR3 Antibody - Anti-CCR3 antibody IHC of human tonsil. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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CCR3 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Human
IHC, IHC-P
Unconjugated
50 µg/$460
CCR3 Antibody - Anti-CCR3 antibody IHC of human Prostate, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
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Neuroscience
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CCR3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human, Monkey
IHC, IHC-P
Unconjugated
50 µg/$460
CCR3 Antibody - Anti-CCR3 antibody IHC of human lung, respiratory epithelium. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 10 ug/ml.
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CCR3 Mouse anti-Human Monoclonal (5E8) Antibody
Human
Flo, IHC, IHC-P
Unconjugated
50 µg/$515
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CCR3 Rat anti-Human Monoclonal (PE) (11n21) Antibody
Human
Flo
PE Conjugated
100 Tests/$847
CCR3 Antibody - Human peripheral blood granulocytes stained with 5E8 PE and CD16 FITC
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CCR3 Mouse anti-Human Monoclonal (5E8) Antibody
Human
Flo
Unconjugated
100 µg/$329
CCR3 Antibody - Anti-CCR3 antibody IHC of human skin. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CCR3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Mouse, Rat, Human
IHC, IHC-P, WB
Unconjugated
50 µg/$545
CCR3 Antibody - Anti-CCR3 antibody IHC of human lung. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval. Antibody concentration 5 ug/ml.
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CCR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IHC, IHC-P, WB
Unconjugated
50 µg/$460
CCR3 Antibody - Immunohistochemistry of CCR3 in human spleen tissue with CCR3 antibody at 10 µg/mL.
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CCR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
ELISA, IF, IHC, WB
Unconjugated
0.1 mg/$460
CCR3 Antibody - IHC of normal human spleen with Rabbit anti-Human CD193 (RABBIT ANTI HUMAN CD193).
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CCR3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Human
IF, IHC, IHC-P, WB
Unconjugated
0.1 mg/$470
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CCR3 Rabbit anti-Human Polyclonal (C-Terminus) Antibody
Mouse, Rat, Human
IHC, WB
Unconjugated
100 µg/$649
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CCR3 Rat anti-Human Monoclonal (PerCP) (11n21) Antibody
Human
Flo
PerCP Conjugated
100 Tests/$846
CCR3 Antibody - Immunohistochemistry of paraffin-embedded human liver tissue at dilution of 1:100
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CCR3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, IF, IHC, IHC-P, WB
Unconjugated
50 µg/$294; 100 µg/$360
CCR3 Antibody - 1:100 staining human liver carcinoma tissues by IHC-P. The sample was formaldehyde fixed and a heat mediated antigen retrieval step in citrate buffer was performed. The sample was then blocked and incubated with the antibody for 1.5 hours at 22°C. An HRP conjugated goat anti-rabbit antibody was used as the secondary.
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CCR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
IF, IHC, Peptide-ELISA, WB
Unconjugated
100 µl/$379; 200 µl/$421
CCR3 Antibody - Western blot - Anti-CCR3 Picoband antibody
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CCR3 Rabbit anti-Human Polyclonal Antibody
Human
Flo, ICC, IHC, WB
Unconjugated
10 µg/$318; 100 µg/$470
CCR3 Antibody - CCR3 antibody. IHC(P): Human Tonsil Tissue.
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CCR3 Rabbit anti-Human Polyclonal (aa1-20) Antibody
Human
ICC, IHC, IHC-P, WB
Unconjugated
10 µg/$318; 100 µg/$470
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CCR3 Goat anti-Human Polyclonal (aa8-34) Antibody
Human
ELISA, ICC, IHC, WB
Unconjugated
100 µg/$556
CCR3 Antibody - Anti-CD193 rabbit polyclonal antibody at 1:500 dilution. Lane A: Daudi Whole Cell Lysate. Lane B: K562 Whole Cell Lysate. Lysates/proteins at 30 ug per lane. Secondary: Goat Anti-Rabbit IgG H&L (Dylight 800) at 1/10000 dilution. Developed using the Odyssey technique. Performed under reducing conditions. Predicted band size: 43 kDa. Observed band size: 62 kDa.
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CCR3 Rabbit anti-Human Polyclonal (Preservative Free) Antibody
Human
ICC, IF, IP, WB
Unconjugated, Preservative Free
100 µl/$412
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CCR3 Mouse anti-Human Monoclonal (8E9H10) Antibody
Human
ELISA, Flo, WB
Unconjugated
100 µl/$459
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CCR3 Rabbit anti-Human Polyclonal (N-Terminus) Antibody
Human
IHC, WB
Unconjugated
40 µg/$485
CCR3 Antibody - Western blot testing of human 1) Jurkat, 2) HepG2, 3) MCF7, 4) U-87 MG, 5) CCRF-CEM, 6) rat brain, 7) mouse brain and 8) mouse testis lysate wtih CCR3 antibody at 0.5ug/ml. Expected molecular weight: 40~55 kDa.
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CCR3 Rabbit anti-Human Polyclonal Antibody
Mouse, Rat, Human
Flo, WB
Unconjugated
100 µg/$575
CCR3 Antibody - Western blot of CCR3 Antibody in Jurkat cell line lysates (35 ug/lane). CCR3 (arrow) was detected using the purified antibody.
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CCR3 Rabbit anti-Human Polyclonal (aa291-318) Antibody
Human
Flo, WB
Unconjugated
400 µl/$393
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CCR3 Rabbit anti-Human Polyclonal (aa291-318) Antibody
Human
ELISA, WB
Unconjugated
200 µl/$734
CCR3 Antibody - Western blot of CKR-3 antibody
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CCR3 Rabbit anti-Human Polyclonal (1-50 aa, N-terminal) Antibody
Human
ELISA, WB
Unconjugated
50 µg/$295; 100 µg/$335; 200 µg/$394
CCR3 Antibody - Western blot analysis of lysate from L929 cells, using CCR3 Antibody.
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CCR3 Rabbit anti-Human Polyclonal Antibody
Human
ELISA, WB
Unconjugated
50 µl/$334; 100 µl/$397
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For RESEARCH USE ONLY. Intended for use by laboratory professionals. Not intended for human diagnostic or therapeutic purposes.

The data on this page has been compiled from LifeSpan internal sources, the National Center for Biotechnology Information (NCBI), and The Universal Protein Resource (UniProt).