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| Catalog Number | Size | Price |
|---|---|---|
| LS-A6600-50 | 50 µg (1 mg/ml) | $440 |
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PathPlus™ Polyclonal Rabbit anti‑Human FFAR2 / GPR43 Antibody (Extracellular Domain, IHC) LS‑A6600
PathPlus™ Polyclonal Rabbit anti‑Human FFAR2 / GPR43 Antibody (Extracellular Domain, IHC) LS‑A6600
Antibody:
FFAR2 / GPR43 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Overview
Antibody:
FFAR2 / GPR43 Rabbit anti-Human Polyclonal (Extracellular Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human
Format:
Unconjugated, Unmodified
Specifications
Description
Free fatty acid receptor 2 (FFAR2) is a G protein-coupled receptor that is activated by a major product of dietary fiber digestion, the short chain fatty acids (SCFAs), and that plays a role in the regulation of whole-body energy homeostasis and in intestinal immunity. FFAR2 regulates the production of LEP/Leptin, a hormone acting on the central nervous system to inhibit food intake and the whole-body's energy homeostasis through adipogenesis regulating both differentiation and lipid storage of adipocytes. FFAR2 plays a role in the resolution of the inflammatory response and control chemotaxis in neutrophils.
References: The UniProt Consortium. Nucleic Acids Res. 47: D506-515 (2019); Nucleic Acids Res. 2016 Jan 4;44(D1):D733-45, PMID:26553804
Target
Human FFAR2 / GPR43
Synonyms
FFAR2 | FFA2R | Free fatty acid receptor 2 | G protein-coupled receptor 43 | G-protein coupled receptor 43 | LSSIG | GPR43 | Gpcr43
Host
Rabbit
Reactivity
Human
(tested or 100% immunogen sequence identity)
Predicted
Monkey (at least 90% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 17 amino acid peptide from 2nd extracellular domain of human GPR43. Percent identity with other species by BLAST analysis: Human, Gorilla (100%); Monkey (94%); Mouse, Rat, Dog, Panda, Rabbit, Pig (88%); Horse, Opossum (82%).
Epitope
Extracellular Domain
Specificity
Human GPR43. BLAST analysis of the peptide immunogen showed no homology with other human proteins, except FFAR3 (47%).
Applications
- IHC
- IHC - Paraffin (5 - 10 µg/ml)
|
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents
ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
|
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
About FFAR2 / GPR43
Validation
Brain, Glioblastoma
Brain, Glioblastoma
Brain, medulla
Brain, medulla
Brain, Hypothalamus
Brain, Hypothalamus
Anti-GPR43 antibody IHC of human lung, alveolar macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR43 antibody IHC of human lung, alveolar macrophages. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FFAR2 / GPR43 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FFAR2 / GPR43 antibody IHC of human Lymph Node, Hodgkins Lymphoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FFAR2 / GPR43 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FFAR2 / GPR43 antibody IHC of human Colon, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FFAR2 / GPR43 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-FFAR2 / GPR43 antibody IHC of human Pancreas, Carcinoma. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
Human Thymus: Formalin-Fixed, Paraffin-Embedded (FFPE)
See More About...
LSBio Ratings
PathPlus™ FFAR2 / GPR43 Antibody (Extracellular Domain) for IHC LS-A6600 has an LSBio Rating of
Laboratory Validation Score (5)
Learn more about The LSBio Ratings Algorithm
Publications (0)
Customer Reviews (0)
Featured Products
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin
Species:
Human, Monkey, Mouse, Rat, Pig
Applications:
IHC, IHC - Paraffin
Species:
Human
Applications:
IHC, IHC - Paraffin, ELISA
Species:
Human
Applications:
IHC, IHC - Paraffin, Immunofluorescence, Peptide Enzyme-Linked Immunosorbent Assay
Request SDS/MSDS
To request an SDS/MSDS form for this product, please contact our Technical Support department at:
Technical.Support@LSBio.com
Requested From: United States
Date Requested: 11/3/2024
Date Requested: 11/3/2024
