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Catalog Number Size Price
LS-A527-50 50 µg (1 mg/ml) $440 
GPR173 / SREB3 Antibody - Brain, Glioblastoma
GPR173 / SREB3 Antibody - Anti-GPR173 antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPR173 / SREB3 Antibody - Brain, Alzheimer's disease, senile plaque
GPR173 / SREB3 Antibody - Brain, Globus Pallidus
GPR173 / SREB3 Antibody - Brain, Glioblastoma
GPR173 / SREB3 Antibody - Anti-GPR173 antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
GPR173 / SREB3 Antibody - Brain, Alzheimer's disease, senile plaque
GPR173 / SREB3 Antibody - Brain, Globus Pallidus
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PathPlus™ Polyclonal Rabbit anti‑Human GPR173 / SREB3 Antibody (Transmembrane Domain, IHC) LS‑A527

PathPlus™ Polyclonal Rabbit anti‑Human GPR173 / SREB3 Antibody (Transmembrane Domain, IHC) LS‑A527

Antibody:
GPR173 / SREB3 Rabbit anti-Human Polyclonal (Transmembrane Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Rabbit
Format:
Unconjugated, Unmodified
Price
Catalog Number
$440
LS-A527-50

Toll Free North America
206-374-1102
For Research Use Only

Overview

Antibody:
GPR173 / SREB3 Rabbit anti-Human Polyclonal (Transmembrane Domain) Antibody
Application:
IHC, IHC-P
Reactivity:
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Rabbit
Format:
Unconjugated, Unmodified

Specifications

Description
GPR173 (SREB3) is a member of the SREB (Super-Conserved Receptor Expressed in Brain) family of GPCRs, and is an Orphan-A GPCR that is believed to be a required receptor for the binding and action of Phoenixin (PNX). PNX is a peptide involved in the rodent reproductive cycle and possibly human reproductive processes as well. Phoenixin is also involved in regulating pain and anxiety-related behavior and has been shown to enhance memory formation. Phoenixin and possibly also its receptor GPR173 may be of interest in therapies for memory-related diseases. In immunohistochemistry, GPR173 has membranous positivity in several brain regions, including the cerebellum, cerebrum, and pituitary, and in lower levels in other tissues. References: Peptides. 2018 Aug;106:45-48, PMID: 29933026; Brain Res. 2015 Dec 10;1629:298-308, PMID: 26505917
Target
Human GPR173 / SREB3
Synonyms
GPR173 | G protein coupled receptor 173 | G-protein coupled receptor 173 | G protein-coupled receptor 173 | SREB3
Host
Rabbit
Reactivity
Human, Monkey, Mouse, Rat, Bat, Bovine, Dog, Hamster, Rabbit (tested or 100% immunogen sequence identity)
Clonality
Polyclonal
Conjugations
Unconjugated
Purification
Immunoaffinity purified
Modifications
Unmodified
Immunogen
Synthetic 19 amino acid peptide from 5th transmembrane domain of human GPR173. Percent identity with other species by BLAST analysis: Human, Gorilla, Gibbon, Monkey, Marmoset, Mouse, Rat, Hamster, Elephant, Panda, Dog, Bat, Bovine, Rabbit (100%); Opossum (95%).
Epitope
Transmembrane Domain
Specificity
Human GPR173. BLAST analysis of the peptide immunogen showed no homology with other human proteins.
Applications
  • IHC
  • IHC - Paraffin (2 µg/ml)
Performing IHC? See our complete line of Immunohistochemistry Reagents including antigen retrieval solutions, blocking agents ABC Detection Kits and polymers, biotinylated secondary antibodies, substrates and more.
Presentation
PBS, 0.1% Sodium Azide
Storage
Aliquot and store undiluted at -20°C or below for up to 1 year. Can be stored undiluted at 4°C for up to 1 month. Avoid freeze-thaw cycles.
Restrictions
For research use only. Intended for use by laboratory professionals.
Guarantee
This antibody carries the LSBio 100% Guarantee.
LSBio Guarantee
About GPR173 / SREB3
Q9NS66 NM_018969 NP_061842.1

Validation

GPR173 / SREB3 Antibody - Brain, Glioblastoma
Brain, Glioblastoma
Brain, Glioblastoma

GPR173 / SREB3 Antibody - Anti-GPR173 antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR173 antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.
Anti-GPR173 antibody IHC of human brain, neuron. Immunohistochemistry of formalin-fixed, paraffin-embedded tissue after heat-induced antigen retrieval.

GPR173 / SREB3 Antibody - Brain, Alzheimer's disease, senile plaque
Brain, Alzheimer's disease, senile plaque
Brain, Alzheimer's disease, senile plaque

GPR173 / SREB3 Antibody - Brain, Globus Pallidus
Brain, Globus Pallidus
Brain, Globus Pallidus

LSBio Ratings

PathPlus™ GPR173 / SREB3 Antibody (Transmembrane Domain) for IHC LS-A527 has an LSBio Rating of
Laboratory Validation Score (5)

Publications (0)

Customer Reviews (0)


Request SDS/MSDS

To request an SDS/MSDS form for this product, please contact our Technical Support department at:

Technical.Support@LSBio.com

Requested From: United States
Date Requested: 10/9/2024